Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1031

Experiment: 7H9 with Rifampicin 0.00045 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1030 and Rv1031 overlap by 1 nucleotidesRv1031 and Rv1032c are separated by 3 nucleotides Rv1030: Rv1030 - Probable potassium-transporting P-type ATPase B chain KdpB (potassium-translocating ATPase B chain) (ATP phosphohydrolase [potassium-transporting] B chain) (potassium binding and translocating subunit B), at 1,153,724 to 1,155,853 Rv1030 Rv1031: Rv1031 - Probable potassium-transporting ATPase C chain KdpC (potassium-translocating ATPase C chain) (ATP phosphohydrolase [potassium-transporting] C chain) (potassium binding and translocating subunit C), at 1,155,853 to 1,156,422 Rv1031 Rv1032c: Rv1032c - Two component sensor histidine kinase TrcS, at 1,156,426 to 1,157,955 Rv1032c Position (kb) 1155 1156 1157Strain fitness (log2 ratio) -1 0 1at 1155.082 kb on - strand, within Rv1030at 1155.412 kb on + strand, within Rv1030at 1155.413 kb on - strand, within Rv1030at 1155.563 kb on + strand, within Rv1030at 1155.564 kb on - strand, within Rv1030at 1155.773 kb on + strandat 1155.773 kb on + strandat 1155.774 kb on - strandat 1155.774 kb on - strandat 1155.802 kb on + strandat 1156.045 kb on + strand, within Rv1031at 1156.046 kb on - strand, within Rv1031at 1156.082 kb on - strand, within Rv1031at 1156.302 kb on + strand, within Rv1031at 1156.303 kb on - strand, within Rv1031at 1156.303 kb on - strand, within Rv1031at 1156.737 kb on + strand, within Rv1032cat 1156.738 kb on - strand, within Rv1032cat 1156.759 kb on + strand, within Rv1032cat 1156.759 kb on + strand, within Rv1032cat 1156.916 kb on - strand, within Rv1032cat 1157.227 kb on - strand, within Rv1032cat 1157.227 kb on - strand, within Rv1032cat 1157.271 kb on + strand, within Rv1032cat 1157.272 kb on - strand, within Rv1032c

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Rifampicin 0.00045 ug/mL
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1,155,082 - Rv1030 0.64 +0.6
1,155,412 + Rv1030 0.79 +0.5
1,155,413 - Rv1030 0.79 +1.2
1,155,563 + Rv1030 0.86 -0.2
1,155,564 - Rv1030 0.86 +1.4
1,155,773 + -0.6
1,155,773 + +0.2
1,155,774 - -0.3
1,155,774 - -0.6
1,155,802 + +0.4
1,156,045 + Rv1031 0.34 +0.4
1,156,046 - Rv1031 0.34 -0.2
1,156,082 - Rv1031 0.40 -0.3
1,156,302 + Rv1031 0.79 -0.3
1,156,303 - Rv1031 0.79 -0.0
1,156,303 - Rv1031 0.79 +0.9
1,156,737 + Rv1032c 0.20 +1.0
1,156,738 - Rv1032c 0.20 -0.3
1,156,759 + Rv1032c 0.22 +0.7
1,156,759 + Rv1032c 0.22 -0.3
1,156,916 - Rv1032c 0.32 +0.1
1,157,227 - Rv1032c 0.52 -0.0
1,157,227 - Rv1032c 0.52 -1.4
1,157,271 + Rv1032c 0.55 +0.6
1,157,272 - Rv1032c 0.55 +1.0

Or see this region's nucleotide sequence