Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2616

Experiment: no stress control

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2615c and Rv2616 are separated by 344 nucleotidesRv2616 and Rv2617c are separated by 16 nucleotidesRv2617c and Rv2618 are separated by 146 nucleotides Rv2615c: Rv2615c - PE-PGRS family protein PE_PGRS45, at 2,943,600 to 2,944,985 Rv2615c Rv2616: Rv2616 - Conserved protein, at 2,945,330 to 2,945,830 Rv2616 Rv2617c: Rv2617c - Probable transmembrane protein, at 2,945,847 to 2,946,287 Rv2617c Rv2618: Rv2618 - Conserved hypothetical protein, at 2,946,434 to 2,947,111 Rv2618 Position (kb) 2945 2946Strain fitness (log2 ratio) -2 -1 0 1 2 3at 2945.411 kb on + strand, within Rv2616at 2945.603 kb on + strand, within Rv2616at 2945.603 kb on + strand, within Rv2616at 2945.603 kb on + strand, within Rv2616at 2945.604 kb on - strand, within Rv2616at 2945.604 kb on - strand, within Rv2616at 2945.813 kb on + strandat 2945.814 kb on - strandat 2946.071 kb on - strand, within Rv2617cat 2946.071 kb on - strand, within Rv2617cat 2946.124 kb on + strand, within Rv2617cat 2946.124 kb on + strand, within Rv2617cat 2946.124 kb on + strand, within Rv2617cat 2946.124 kb on + strand, within Rv2617cat 2946.124 kb on + strand, within Rv2617cat 2946.124 kb on + strand, within Rv2617cat 2946.124 kb on + strand, within Rv2617cat 2946.124 kb on + strand, within Rv2617cat 2946.124 kb on + strand, within Rv2617cat 2946.125 kb on - strand, within Rv2617cat 2946.216 kb on + strand, within Rv2617cat 2946.217 kb on - strand, within Rv2617cat 2946.217 kb on - strand, within Rv2617cat 2946.220 kb on + strand, within Rv2617cat 2946.220 kb on + strand, within Rv2617cat 2946.220 kb on + strand, within Rv2617cat 2946.220 kb on + strand, within Rv2617cat 2946.220 kb on + strand, within Rv2617cat 2946.220 kb on + strand, within Rv2617cat 2946.220 kb on + strand, within Rv2617cat 2946.220 kb on + strand, within Rv2617cat 2946.220 kb on + strand, within Rv2617cat 2946.221 kb on - strand, within Rv2617cat 2946.221 kb on - strand, within Rv2617cat 2946.221 kb on - strand, within Rv2617cat 2946.221 kb on - strand, within Rv2617cat 2946.287 kb on + strandat 2946.288 kb on - strandat 2946.288 kb on - strandat 2946.288 kb on - strandat 2946.288 kb on - strandat 2946.335 kb on - strandat 2946.588 kb on - strand, within Rv2618at 2946.641 kb on + strand, within Rv2618at 2946.641 kb on + strand, within Rv2618at 2946.786 kb on - strand, within Rv2618

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Per-strain Table

Position Strand Gene LocusTag Fraction no stress control
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2,945,411 + Rv2616 0.16 +3.3
2,945,603 + Rv2616 0.54 -0.1
2,945,603 + Rv2616 0.54 +0.3
2,945,603 + Rv2616 0.54 -0.2
2,945,604 - Rv2616 0.55 -0.3
2,945,604 - Rv2616 0.55 -2.5
2,945,813 + -0.3
2,945,814 - +0.0
2,946,071 - Rv2617c 0.51 -1.0
2,946,071 - Rv2617c 0.51 -0.0
2,946,124 + Rv2617c 0.63 +0.5
2,946,124 + Rv2617c 0.63 -0.1
2,946,124 + Rv2617c 0.63 +0.1
2,946,124 + Rv2617c 0.63 +0.2
2,946,124 + Rv2617c 0.63 +0.1
2,946,124 + Rv2617c 0.63 +1.9
2,946,124 + Rv2617c 0.63 +1.4
2,946,124 + Rv2617c 0.63 -0.5
2,946,124 + Rv2617c 0.63 -0.4
2,946,125 - Rv2617c 0.63 +0.1
2,946,216 + Rv2617c 0.84 -0.5
2,946,217 - Rv2617c 0.84 -0.6
2,946,217 - Rv2617c 0.84 +0.1
2,946,220 + Rv2617c 0.85 -0.2
2,946,220 + Rv2617c 0.85 -0.4
2,946,220 + Rv2617c 0.85 +0.3
2,946,220 + Rv2617c 0.85 +0.1
2,946,220 + Rv2617c 0.85 +0.1
2,946,220 + Rv2617c 0.85 +2.1
2,946,220 + Rv2617c 0.85 -0.2
2,946,220 + Rv2617c 0.85 -0.1
2,946,220 + Rv2617c 0.85 -0.0
2,946,221 - Rv2617c 0.85 -0.3
2,946,221 - Rv2617c 0.85 -1.1
2,946,221 - Rv2617c 0.85 +0.9
2,946,221 - Rv2617c 0.85 -0.5
2,946,287 + -0.1
2,946,288 - -0.4
2,946,288 - -1.1
2,946,288 - -0.3
2,946,288 - +0.3
2,946,335 - -0.2
2,946,588 - Rv2618 0.23 +0.3
2,946,641 + Rv2618 0.31 -1.1
2,946,641 + Rv2618 0.31 -0.7
2,946,786 - Rv2618 0.52 -0.7

Or see this region's nucleotide sequence