Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3915

Experiment: no stress control

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv3913 and Rv3914 overlap by 4 nucleotidesRv3914 and Rv3915 are separated by 109 nucleotidesRv3915 and Rv3916c are separated by 20 nucleotides Rv3913: Rv3913 - Probable thioredoxin reductase TrxB2 (TRXR) (TR), at 4,401,728 to 4,402,735 Rv3913 Rv3914: Rv3914 - Thioredoxin TrxC (TRX) (MPT46), at 4,402,732 to 4,403,082 Rv3914 Rv3915: Rv3915 - Probable peptidoglycan hydrolase, at 4,403,192 to 4,404,412 Rv3915 Rv3916c: Rv3916c - Conserved hypothetical protein, at 4,404,433 to 4,405,167 Rv3916c Position (kb) 4403 4404 4405Strain fitness (log2 ratio) -1 0 1at 4403.081 kb on - strandat 4403.134 kb on + strandat 4404.411 kb on - strandat 4405.209 kb on - strandat 4405.277 kb on + strand

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Per-strain Table

Position Strand Gene LocusTag Fraction no stress control
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4,403,081 - -0.1
4,403,134 + -0.2
4,404,411 - +0.9
4,405,209 - -1.7
4,405,277 + -0.5

Or see this region's nucleotide sequence