Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3752c

Experiment: no stress control

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv3750c and Rv3751 are separated by 276 nucleotidesRv3751 and GFF3901 are separated by 41 nucleotidesGFF3901 and Rv3752c are separated by 29 nucleotidesRv3752c and Rv3753c are separated by 15 nucleotidesRv3753c and Rv3754 are separated by 199 nucleotides Rv3750c: Rv3750c - Possible excisionase, at 4,198,205 to 4,198,597 Rv3750c Rv3751: Rv3751 - Probable integrase (fragment), at 4,198,874 to 4,199,089 Rv3751 GFF3901 - tRNA-Ser, at 4,199,131 to 4,199,217 GFF3901 Rv3752c: Rv3752c - Possible cytidine/deoxycytidylate deaminase, at 4,199,247 to 4,199,705 Rv3752c Rv3753c: Rv3753c - Conserved protein, at 4,199,721 to 4,200,221 Rv3753c Rv3754: Rv3754 - Prephenate dehydrogenase TyrA (PDH) (hydroxyphenylpyruvate synthase), at 4,200,421 to 4,201,326 Rv3754 Position (kb) 4199 4200Strain fitness (log2 ratio) -1 0 1 2at 4198.266 kb on - strand, within Rv3750cat 4198.433 kb on + strand, within Rv3750cat 4198.497 kb on + strand, within Rv3750cat 4198.497 kb on + strand, within Rv3750cat 4198.498 kb on - strand, within Rv3750cat 4198.498 kb on - strand, within Rv3750cat 4198.623 kb on + strandat 4198.623 kb on + strandat 4198.624 kb on - strandat 4198.624 kb on - strandat 4198.664 kb on + strandat 4198.665 kb on - strandat 4198.707 kb on - strandat 4198.715 kb on + strandat 4198.716 kb on - strandat 4198.850 kb on - strandat 4199.016 kb on - strand, within Rv3751at 4199.016 kb on - strand, within Rv3751at 4200.256 kb on - strandat 4200.334 kb on + strandat 4200.334 kb on + strandat 4200.335 kb on - strandat 4200.338 kb on + strandat 4200.338 kb on + strandat 4200.338 kb on + strandat 4200.339 kb on - strandat 4200.339 kb on - strand

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Per-strain Table

Position Strand Gene LocusTag Fraction no stress control
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4,198,266 - Rv3750c 0.16 +0.1
4,198,433 + Rv3750c 0.58 -1.0
4,198,497 + Rv3750c 0.74 +0.8
4,198,497 + Rv3750c 0.74 -0.6
4,198,498 - Rv3750c 0.75 -0.7
4,198,498 - Rv3750c 0.75 +0.1
4,198,623 + -0.0
4,198,623 + -0.4
4,198,624 - +0.2
4,198,624 - +0.4
4,198,664 + -0.3
4,198,665 - +1.8
4,198,707 - -0.5
4,198,715 + -0.7
4,198,716 - -0.0
4,198,850 - +0.0
4,199,016 - Rv3751 0.66 +0.3
4,199,016 - Rv3751 0.66 -0.1
4,200,256 - -0.2
4,200,334 + -0.1
4,200,334 + -0.1
4,200,335 - -0.2
4,200,338 + -0.5
4,200,338 + -0.3
4,200,338 + +1.1
4,200,339 - -0.5
4,200,339 - -0.5

Or see this region's nucleotide sequence