Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3474

Experiment: no stress control

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv3472 and Rv3473c are separated by 79 nucleotidesRv3473c and Rv3474 are separated by 96 nucleotidesRv3474 and Rv3475 overlap by 52 nucleotides Rv3472: Rv3472 - Conserved protein, at 3,889,362 to 3,889,868 Rv3472 Rv3473c: Rv3473c - Possible peroxidase BpoA (non-haem peroxidase), at 3,889,948 to 3,890,733 Rv3473c Rv3474: Rv3474 - Possible transposase for insertion element IS6110 (fragment), at 3,890,830 to 3,891,156 Rv3474 Rv3475: Rv3475 - Possible transposase for insertion element IS6110 [second part], at 3,891,105 to 3,892,091 Rv3475 Position (kb) 3890 3891 3892Strain fitness (log2 ratio) -2 -1 0 1at 3889.897 kb on + strandat 3889.897 kb on + strandat 3889.981 kb on + strandat 3889.982 kb on - strandat 3890.025 kb on + strandat 3890.025 kb on + strandat 3890.025 kb on + strandat 3890.026 kb on - strandat 3890.200 kb on + strand, within Rv3473cat 3890.201 kb on - strand, within Rv3473cat 3890.220 kb on + strand, within Rv3473cat 3890.221 kb on - strand, within Rv3473cat 3890.253 kb on - strand, within Rv3473cat 3890.253 kb on - strand, within Rv3473cat 3890.327 kb on + strand, within Rv3473cat 3890.327 kb on + strand, within Rv3473cat 3890.328 kb on - strand, within Rv3473c

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Per-strain Table

Position Strand Gene LocusTag Fraction no stress control
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3,889,897 + +0.5
3,889,897 + -0.6
3,889,981 + +0.3
3,889,982 - +0.2
3,890,025 + -0.4
3,890,025 + -0.4
3,890,025 + -0.0
3,890,026 - -2.0
3,890,200 + Rv3473c 0.32 +0.0
3,890,201 - Rv3473c 0.32 -0.6
3,890,220 + Rv3473c 0.35 -0.3
3,890,221 - Rv3473c 0.35 +0.2
3,890,253 - Rv3473c 0.39 -0.1
3,890,253 - Rv3473c 0.39 -2.2
3,890,327 + Rv3473c 0.48 +0.7
3,890,327 + Rv3473c 0.48 +0.3
3,890,328 - Rv3473c 0.48 +0.0

Or see this region's nucleotide sequence