Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3464

Experiment: no stress control

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv3463 and Rv3464 are separated by 72 nucleotidesRv3464 and Rv3465 are separated by 1 nucleotidesRv3465 and Rv3466 are separated by 82 nucleotides Rv3463: Rv3463 - Conserved protein, at 3,880,907 to 3,881,764 Rv3463 Rv3464: Rv3464 - dTDP-glucose 4,6-dehydratase RmlB, at 3,881,837 to 3,882,832 Rv3464 Rv3465: Rv3465 - dTDP-4-dehydrorhamnose 3,5-epimerase RmlC (dTDP-4-keto-6-deoxyglucose 3,5-epimerase) (dTDP-L-rhamnose synthetase) (thymidine diphospho-4-keto-rhamnose 3,5-epimerase), at 3,882,834 to 3,883,442 Rv3465 Rv3466: Rv3466 - Conserved hypothetical protein, at 3,883,525 to 3,884,193 Rv3466 Position (kb) 3881 3882 3883Strain fitness (log2 ratio) -1 0 1at 3880.946 kb on - strandat 3881.238 kb on - strand, within Rv3463at 3881.250 kb on - strand, within Rv3463at 3881.267 kb on + strand, within Rv3463at 3881.271 kb on + strand, within Rv3463at 3881.378 kb on + strand, within Rv3463at 3881.379 kb on - strand, within Rv3463at 3881.454 kb on - strand, within Rv3463at 3881.513 kb on - strand, within Rv3463at 3881.516 kb on + strand, within Rv3463at 3881.517 kb on - strand, within Rv3463at 3881.517 kb on - strand, within Rv3463at 3881.534 kb on + strand, within Rv3463at 3881.534 kb on + strand, within Rv3463at 3881.690 kb on - strandat 3881.825 kb on - strand

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Per-strain Table

Position Strand Gene LocusTag Fraction no stress control
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3,880,946 - -0.7
3,881,238 - Rv3463 0.39 +0.4
3,881,250 - Rv3463 0.40 +0.1
3,881,267 + Rv3463 0.42 -0.3
3,881,271 + Rv3463 0.42 +0.4
3,881,378 + Rv3463 0.55 -0.6
3,881,379 - Rv3463 0.55 -0.2
3,881,454 - Rv3463 0.64 +0.2
3,881,513 - Rv3463 0.71 -0.3
3,881,516 + Rv3463 0.71 -1.0
3,881,517 - Rv3463 0.71 +0.1
3,881,517 - Rv3463 0.71 -0.3
3,881,534 + Rv3463 0.73 -1.5
3,881,534 + Rv3463 0.73 +0.5
3,881,690 - -0.2
3,881,825 - -0.7

Or see this region's nucleotide sequence