Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3396c

Experiment: no stress control

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv3395c and Rv3395A are separated by 82 nucleotidesRv3395A and Rv3396c are separated by 155 nucleotidesRv3396c and Rv3397c are separated by 11 nucleotidesRv3397c and Rv3398c are separated by 28 nucleotides Rv3395c: Rv3395c - Conserved hypothetical protein, at 3,811,022 to 3,811,636 Rv3395c Rv3395A: Rv3395A - Probable membrane protein, at 3,811,719 to 3,812,345 Rv3395A Rv3396c: Rv3396c - Probable GMP synthase [glutamine-hydrolyzing] GuaA (glutamine amidotransferase) (GMP synthetase), at 3,812,501 to 3,814,078 Rv3396c Rv3397c: Rv3397c - Probable phytoene synthase PhyA, at 3,814,090 to 3,814,998 Rv3397c Rv3398c: Rv3398c - Probable multifunctional geranylgeranyl pyrophosphate synthetase IdsA1 (GGPP synthetase) (ggppsase) (geranylgeranyl diphosphate synthase): dimethylallyltransferase (prenyltransferase) (geranyl-diphosphate synthase) + geranyltranstransferase (farnesyl-diphosphate synthase) (farnesyl-pyrophosphate synthetase) (farnesyl diphosphate synthetase) (FPP synthetase) + farnesyltranstransferase (geranylgeranyl-diphosphate synthase), at 3,815,027 to 3,816,106 Rv3398c Position (kb) 3812 3813 3814 3815Strain fitness (log2 ratio) -1 0 1at 3811.730 kb on + strandat 3811.730 kb on + strandat 3811.730 kb on + strandat 3811.777 kb on + strandat 3812.082 kb on + strand, within Rv3395Aat 3812.083 kb on - strand, within Rv3395Aat 3812.083 kb on - strand, within Rv3395Aat 3812.083 kb on - strand, within Rv3395Aat 3812.230 kb on + strand, within Rv3395Aat 3812.343 kb on + strandat 3812.343 kb on + strandat 3812.344 kb on - strandat 3812.392 kb on + strandat 3812.392 kb on + strandat 3812.433 kb on + strandat 3812.434 kb on - strandat 3812.449 kb on + strandat 3812.449 kb on + strandat 3812.449 kb on + strandat 3812.449 kb on + strandat 3812.449 kb on + strandat 3812.450 kb on - strandat 3812.450 kb on - strandat 3812.486 kb on + strandat 3812.502 kb on + strandat 3814.265 kb on + strand, within Rv3397cat 3814.442 kb on - strand, within Rv3397c

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Per-strain Table

Position Strand Gene LocusTag Fraction no stress control
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3,811,730 + -0.8
3,811,730 + -1.3
3,811,730 + -1.3
3,811,777 + -0.3
3,812,082 + Rv3395A 0.58 +0.1
3,812,083 - Rv3395A 0.58 -1.0
3,812,083 - Rv3395A 0.58 -0.3
3,812,083 - Rv3395A 0.58 -0.3
3,812,230 + Rv3395A 0.81 +0.3
3,812,343 + +0.8
3,812,343 + -0.4
3,812,344 - -1.2
3,812,392 + -0.8
3,812,392 + +0.5
3,812,433 + -0.9
3,812,434 - -0.7
3,812,449 + +0.7
3,812,449 + -1.0
3,812,449 + -0.6
3,812,449 + -1.1
3,812,449 + -0.7
3,812,450 - -0.1
3,812,450 - -0.3
3,812,486 + +0.8
3,812,502 + -0.1
3,814,265 + Rv3397c 0.19 +0.5
3,814,442 - Rv3397c 0.39 -0.3

Or see this region's nucleotide sequence