Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3336c

Experiment: no stress control

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv3334 and Rv3335c are separated by 33 nucleotidesRv3335c and Rv3336c are separated by 20 nucleotidesRv3336c and Rv3337 are separated by 24 nucleotidesRv3337 and Rv3338 overlap by 139 nucleotidesRv3338 and Rv3339c are separated by 66 nucleotides Rv3334: Rv3334 - Probable transcriptional regulatory protein (probably MerR-family), at 3,721,257 to 3,721,697 Rv3334 Rv3335c: Rv3335c - Probable conserved integral membrane protein, at 3,721,731 to 3,722,600 Rv3335c Rv3336c: Rv3336c - Probable tryptophanyl-tRNA synthetase TrpS (tryptophan--tRNA ligase) (TRPRS) (tryptophan translase), at 3,722,621 to 3,723,631 Rv3336c Rv3337: Rv3337 - Conserved hypothetical protein, at 3,723,656 to 3,724,042 Rv3337 Rv3338: Rv3338 - Conserved hypothetical protein, at 3,723,904 to 3,724,548 Rv3338 Rv3339c: Rv3339c - Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP), at 3,724,615 to 3,725,844 Rv3339c Position (kb) 3722 3723 3724Strain fitness (log2 ratio) -1 0 1at 3721.851 kb on + strand, within Rv3335cat 3721.862 kb on - strand, within Rv3335cat 3722.154 kb on + strand, within Rv3335cat 3722.471 kb on - strand, within Rv3335cat 3722.622 kb on + strandat 3723.715 kb on + strand, within Rv3337at 3723.727 kb on + strand, within Rv3337at 3723.728 kb on - strand, within Rv3337at 3723.769 kb on - strand, within Rv3337at 3723.774 kb on + strand, within Rv3337at 3723.774 kb on + strand, within Rv3337at 3723.774 kb on + strand, within Rv3337at 3723.775 kb on - strand, within Rv3337at 3723.849 kb on + strand, within Rv3337at 3723.849 kb on + strand, within Rv3337at 3723.849 kb on + strand, within Rv3337at 3723.850 kb on - strand, within Rv3337at 3723.973 kb on - strandat 3723.973 kb on - strandat 3724.105 kb on - strand, within Rv3338at 3724.277 kb on - strand, within Rv3338at 3724.547 kb on - strandat 3724.547 kb on - strand

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Per-strain Table

Position Strand Gene LocusTag Fraction no stress control
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3,721,851 + Rv3335c 0.14 -0.1
3,721,862 - Rv3335c 0.15 -0.7
3,722,154 + Rv3335c 0.49 -0.2
3,722,471 - Rv3335c 0.85 -0.3
3,722,622 + -0.4
3,723,715 + Rv3337 0.15 -0.5
3,723,727 + Rv3337 0.18 -0.3
3,723,728 - Rv3337 0.19 -1.3
3,723,769 - Rv3337 0.29 -0.1
3,723,774 + Rv3337 0.30 +0.2
3,723,774 + Rv3337 0.30 -0.5
3,723,774 + Rv3337 0.30 -0.4
3,723,775 - Rv3337 0.31 +0.4
3,723,849 + Rv3337 0.50 +0.6
3,723,849 + Rv3337 0.50 -0.0
3,723,849 + Rv3337 0.50 +0.2
3,723,850 - Rv3337 0.50 -1.2
3,723,973 - -0.2
3,723,973 - +0.2
3,724,105 - Rv3338 0.31 +0.8
3,724,277 - Rv3338 0.58 +0.7
3,724,547 - -0.1
3,724,547 - -1.4

Or see this region's nucleotide sequence