Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2746c

Experiment: no stress control

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2744c and Rv2745c are separated by 129 nucleotidesRv2745c and Rv2746c are separated by 70 nucleotidesRv2746c and Rv2747 are separated by 30 nucleotidesRv2747 and Rv2748c are separated by 68 nucleotides Rv2744c: Rv2744c - Conserved 35 kDa alanine rich protein, at 3,057,251 to 3,058,063 Rv2744c Rv2745c: Rv2745c - Transcriptional regulatory protein ClgR, at 3,058,193 to 3,058,531 Rv2745c Rv2746c: Rv2746c - Probable PGP synthase PgsA3 (CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase) (phosphatidylglycerophosphate synthase), at 3,058,602 to 3,059,231 Rv2746c Rv2747: Rv2747 - Probable L-glutamate alpha-N-acetyltranferase ArgA (alpha-N-acetylglutamate synthase), at 3,059,262 to 3,059,786 Rv2747 Rv2748c: Rv2748c - Possible cell division transmembrane protein FtsK, at 3,059,855 to 3,062,506 Rv2748c Position (kb) 3058 3059 3060Strain fitness (log2 ratio) -1 0 1at 3057.771 kb on + strand, within Rv2744cat 3057.771 kb on + strand, within Rv2744cat 3057.772 kb on - strand, within Rv2744cat 3058.032 kb on + strandat 3058.032 kb on + strandat 3058.033 kb on - strandat 3058.033 kb on - strandat 3058.046 kb on - strandat 3058.194 kb on + strandat 3058.195 kb on - strandat 3058.361 kb on - strand, within Rv2745cat 3058.422 kb on + strand, within Rv2745cat 3058.422 kb on + strand, within Rv2745cat 3059.173 kb on - strandat 3059.173 kb on - strandat 3059.785 kb on - strand

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Per-strain Table

Position Strand Gene LocusTag Fraction no stress control
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3,057,771 + Rv2744c 0.64 +0.2
3,057,771 + Rv2744c 0.64 -0.7
3,057,772 - Rv2744c 0.64 -0.6
3,058,032 + -0.9
3,058,032 + +0.1
3,058,033 - +1.4
3,058,033 - -1.0
3,058,046 - -1.7
3,058,194 + -0.6
3,058,195 - +0.4
3,058,361 - Rv2745c 0.50 -0.7
3,058,422 + Rv2745c 0.68 +0.4
3,058,422 + Rv2745c 0.68 -0.6
3,059,173 - -1.1
3,059,173 - -0.4
3,059,785 - -0.2

Or see this region's nucleotide sequence