Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2727c

Experiment: no stress control

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2725c and Rv2726c are separated by 16 nucleotidesRv2726c and Rv2727c are separated by 24 nucleotidesRv2727c and Rv2728c overlap by 4 nucleotidesRv2728c and Rv2729c are separated by 108 nucleotides Rv2725c: Rv2725c - Probable GTP-binding protein HflX, at 3,037,427 to 3,038,914 Rv2725c Rv2726c: Rv2726c - Probable diaminopimelate epimerase DapF (DAP epimerase), at 3,038,931 to 3,039,800 Rv2726c Rv2727c: Rv2727c - Probable tRNA delta(2)-isopentenylpyrophosphate transferase MiaA (IPP transferase) (isopentenyl-diphosphate:tRNA isopentenyltransferase) (iptase) (IPPT), at 3,039,825 to 3,040,769 Rv2727c Rv2728c: Rv2728c - Conserved alanine rich protein, at 3,040,766 to 3,041,461 Rv2728c Rv2729c: Rv2729c - Probable conserved integral membrane alanine valine and leucine rich protein, at 3,041,570 to 3,042,475 Rv2729c Position (kb) 3039 3040 3041Strain fitness (log2 ratio) -2 -1 0 1 2 3at 3038.850 kb on + strandat 3038.850 kb on + strandat 3038.850 kb on + strandat 3038.850 kb on + strandat 3038.851 kb on - strandat 3038.851 kb on - strandat 3038.851 kb on - strandat 3038.857 kb on + strandat 3038.914 kb on + strandat 3038.914 kb on + strandat 3038.915 kb on - strandat 3040.819 kb on - strandat 3040.981 kb on - strand, within Rv2728cat 3041.031 kb on - strand, within Rv2728cat 3041.177 kb on - strand, within Rv2728cat 3041.196 kb on - strand, within Rv2728cat 3041.196 kb on - strand, within Rv2728cat 3041.473 kb on - strandat 3041.473 kb on - strandat 3041.473 kb on - strandat 3041.651 kb on + strandat 3041.651 kb on + strand

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Per-strain Table

Position Strand Gene LocusTag Fraction no stress control
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3,038,850 + +0.0
3,038,850 + -0.0
3,038,850 + +1.1
3,038,850 + -0.1
3,038,851 - -0.3
3,038,851 - +0.2
3,038,851 - -0.9
3,038,857 + +0.4
3,038,914 + +0.1
3,038,914 + +0.5
3,038,915 - -0.3
3,040,819 - -0.1
3,040,981 - Rv2728c 0.31 -0.2
3,041,031 - Rv2728c 0.38 +0.2
3,041,177 - Rv2728c 0.59 +2.8
3,041,196 - Rv2728c 0.62 -1.5
3,041,196 - Rv2728c 0.62 +0.1
3,041,473 - -0.4
3,041,473 - -0.4
3,041,473 - -0.6
3,041,651 + -1.8
3,041,651 + -0.2

Or see this region's nucleotide sequence