Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2703

Experiment: no stress control

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2702 and Rv2703 are separated by 179 nucleotidesRv2703 and Rv2704 are separated by 36 nucleotidesRv2704 and Rv2705c overlap by 73 nucleotidesRv2705c and Rv2706c overlap by 4 nucleotides Rv2702: Rv2702 - Polyphosphate glucokinase PpgK (polyphosphate-glucose phosphotransferase), at 3,016,858 to 3,017,655 Rv2702 Rv2703: Rv2703 - RNA polymerase sigma factor SigA (sigma-A), at 3,017,835 to 3,019,421 Rv2703 Rv2704: Rv2704 - Conserved protein, at 3,019,458 to 3,019,886 Rv2704 Rv2705c: Rv2705c - Conserved hypothetical protein, at 3,019,814 to 3,020,203 Rv2705c Rv2706c: Rv2706c - Hypothetical protein, at 3,020,200 to 3,020,457 Rv2706c Position (kb) 3017 3018 3019 3020Strain fitness (log2 ratio) -2 -1 0 1 2at 3017.098 kb on + strand, within Rv2702at 3017.579 kb on + strandat 3017.643 kb on + strandat 3017.643 kb on + strandat 3017.688 kb on + strandat 3017.694 kb on + strandat 3017.694 kb on + strandat 3017.694 kb on + strandat 3017.815 kb on + strandat 3019.446 kb on + strandat 3019.446 kb on + strandat 3019.446 kb on + strandat 3019.674 kb on + strand, within Rv2704at 3019.674 kb on + strand, within Rv2704at 3019.674 kb on + strand, within Rv2704at 3019.675 kb on - strand, within Rv2704at 3019.675 kb on - strand, within Rv2704at 3019.675 kb on - strand, within Rv2704at 3019.675 kb on - strand, within Rv2704at 3019.675 kb on - strand, within Rv2704at 3019.685 kb on + strand, within Rv2704at 3019.796 kb on - strand, within Rv2704at 3019.816 kb on - strandat 3019.819 kb on + strandat 3019.819 kb on + strandat 3019.819 kb on + strandat 3019.820 kb on - strandat 3019.820 kb on - strandat 3019.820 kb on - strandat 3019.926 kb on + strand, within Rv2705cat 3019.960 kb on + strand, within Rv2705cat 3019.961 kb on - strand, within Rv2705cat 3020.092 kb on + strand, within Rv2705cat 3020.092 kb on + strand, within Rv2705cat 3020.093 kb on - strand, within Rv2705cat 3020.093 kb on - strand, within Rv2705cat 3020.095 kb on - strand, within Rv2705cat 3020.095 kb on - strand, within Rv2705cat 3020.165 kb on + strandat 3020.165 kb on + strandat 3020.165 kb on + strandat 3020.166 kb on - strandat 3020.166 kb on - strandat 3020.166 kb on - strandat 3020.356 kb on - strand, within Rv2706c

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Per-strain Table

Position Strand Gene LocusTag Fraction no stress control
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3,017,098 + Rv2702 0.30 -0.6
3,017,579 + -0.6
3,017,643 + -0.6
3,017,643 + -0.5
3,017,688 + +0.7
3,017,694 + +1.8
3,017,694 + +0.3
3,017,694 + -0.2
3,017,815 + -0.8
3,019,446 + +0.0
3,019,446 + -1.3
3,019,446 + -0.6
3,019,674 + Rv2704 0.50 -0.5
3,019,674 + Rv2704 0.50 -1.6
3,019,674 + Rv2704 0.50 -0.2
3,019,675 - Rv2704 0.51 -0.5
3,019,675 - Rv2704 0.51 -0.2
3,019,675 - Rv2704 0.51 -0.2
3,019,675 - Rv2704 0.51 +0.1
3,019,675 - Rv2704 0.51 -0.3
3,019,685 + Rv2704 0.53 -0.0
3,019,796 - Rv2704 0.79 -2.3
3,019,816 - -0.2
3,019,819 + +0.4
3,019,819 + -0.3
3,019,819 + -0.6
3,019,820 - +0.8
3,019,820 - -0.7
3,019,820 - -0.2
3,019,926 + Rv2705c 0.29 -1.3
3,019,960 + Rv2705c 0.37 -1.2
3,019,961 - Rv2705c 0.38 +0.6
3,020,092 + Rv2705c 0.71 -0.4
3,020,092 + Rv2705c 0.71 -0.7
3,020,093 - Rv2705c 0.72 -1.3
3,020,093 - Rv2705c 0.72 -1.1
3,020,095 - Rv2705c 0.72 -0.8
3,020,095 - Rv2705c 0.72 -0.3
3,020,165 + -0.2
3,020,165 + -0.2
3,020,165 + +1.8
3,020,166 - -0.4
3,020,166 - +0.5
3,020,166 - -1.2
3,020,356 - Rv2706c 0.60 -1.0

Or see this region's nucleotide sequence