Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2648

Experiment: no stress control

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2646 and Rv2647 are separated by 109 nucleotidesRv2647 and Rv2648 are separated by 132 nucleotidesRv2648 and Rv2649 overlap by 52 nucleotides Rv2646: Rv2646 - Probable integrase, at 2,970,551 to 2,971,549 Rv2646 Rv2647: Rv2647 - Hypothetical protein, at 2,971,659 to 2,972,027 Rv2647 Rv2648: Rv2648 - Probable transposase for insertion sequence element IS6110 (fragment), at 2,972,160 to 2,972,486 Rv2648 Rv2649: Rv2649 - Probable transposase for insertion sequence element IS6110, at 2,972,435 to 2,973,421 Rv2649 Position (kb) 2972 2973Strain fitness (log2 ratio) -2 -1 0 1 2at 2971.246 kb on + strand, within Rv2646at 2971.246 kb on + strand, within Rv2646at 2971.247 kb on - strand, within Rv2646at 2971.266 kb on - strand, within Rv2646at 2971.409 kb on + strand, within Rv2646at 2971.452 kb on + strandat 2971.452 kb on + strandat 2971.452 kb on + strandat 2971.452 kb on + strandat 2971.453 kb on - strandat 2971.496 kb on + strandat 2971.845 kb on + strand, within Rv2647at 2971.871 kb on + strand, within Rv2647

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Per-strain Table

Position Strand Gene LocusTag Fraction no stress control
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2,971,246 + Rv2646 0.70 +0.1
2,971,246 + Rv2646 0.70 -1.2
2,971,247 - Rv2646 0.70 -0.2
2,971,266 - Rv2646 0.72 +0.2
2,971,409 + Rv2646 0.86 +0.8
2,971,452 + -0.3
2,971,452 + -2.2
2,971,452 + -0.2
2,971,452 + +1.8
2,971,453 - -0.8
2,971,496 + -0.1
2,971,845 + Rv2647 0.50 -0.5
2,971,871 + Rv2647 0.57 +0.8

Or see this region's nucleotide sequence