Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2593c

Experiment: no stress control

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2592c and Rv2593c overlap by 4 nucleotidesRv2593c and Rv2594c overlap by 4 nucleotidesRv2594c and Rv2595 are separated by 108 nucleotidesRv2595 and Rv2596 overlap by 4 nucleotides Rv2592c: Rv2592c - Probable holliday junction DNA helicase RuvB, at 2,923,199 to 2,924,233 Rv2592c Rv2593c: Rv2593c - Probable holliday junction DNA helicase RuvA, at 2,924,230 to 2,924,820 Rv2593c Rv2594c: Rv2594c - Probable crossover junction endodeoxyribonuclease RuvC (holliday junction nuclease) (holliday junction resolvase), at 2,924,817 to 2,925,383 Rv2594c Rv2595: Rv2595 - Possible antitoxin VapB40, at 2,925,492 to 2,925,737 Rv2595 Rv2596: Rv2596 - Possible toxin VapC40. Contains PIN domain., at 2,925,734 to 2,926,138 Rv2596 Position (kb) 2924 2925Strain fitness (log2 ratio) -1 0 1at 2925.462 kb on + strandat 2925.463 kb on - strand

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Per-strain Table

Position Strand Gene LocusTag Fraction no stress control
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2,925,462 + -0.2
2,925,463 - -0.4

Or see this region's nucleotide sequence