Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2580c

Experiment: no stress control

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2579 and Rv2580c are separated by 279 nucleotidesRv2580c and Rv2581c overlap by 4 nucleotidesRv2581c and Rv2582 are separated by 50 nucleotides Rv2579: Rv2579 - Possible haloalkane dehalogenase DhaA (1-chlorohexane halidohydrolase), at 2,903,639 to 2,904,541 Rv2579 Rv2580c: Rv2580c - Probable histidyl-tRNA synthetase HisS (histidine--tRNA ligase) (HISRS) (histidine--translase), at 2,904,821 to 2,906,092 Rv2580c Rv2581c: Rv2581c - Possible glyoxalase II (hydroxyacylglutathione hydrolase) (GLX II), at 2,906,089 to 2,906,763 Rv2581c Rv2582: Rv2582 - Probable peptidyl-prolyl cis-trans isomerase B PpiB (cyclophilin) (PPIase) (rotamase) (peptidylprolyl isomerase), at 2,906,814 to 2,907,740 Rv2582 Position (kb) 2904 2905 2906 2907Strain fitness (log2 ratio) -1 0 1at 2903.880 kb on - strand, within Rv2579at 2903.882 kb on - strand, within Rv2579at 2903.882 kb on - strand, within Rv2579at 2903.882 kb on - strand, within Rv2579at 2903.885 kb on + strand, within Rv2579at 2903.886 kb on - strand, within Rv2579at 2903.886 kb on - strand, within Rv2579at 2903.950 kb on - strand, within Rv2579at 2906.490 kb on - strand, within Rv2581cat 2906.532 kb on - strand, within Rv2581c

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Per-strain Table

Position Strand Gene LocusTag Fraction no stress control
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2,903,880 - Rv2579 0.27 -0.3
2,903,882 - Rv2579 0.27 -0.4
2,903,882 - Rv2579 0.27 -1.2
2,903,882 - Rv2579 0.27 +0.5
2,903,885 + Rv2579 0.27 +1.7
2,903,886 - Rv2579 0.27 +0.0
2,903,886 - Rv2579 0.27 -0.8
2,903,950 - Rv2579 0.34 -0.3
2,906,490 - Rv2581c 0.59 -1.6
2,906,532 - Rv2581c 0.66 -1.5

Or see this region's nucleotide sequence