Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2524c

Experiment: no stress control

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2522c and Rv2523c overlap by 4 nucleotidesRv2523c and Rv2524c are separated by 192 nucleotidesRv2524c and Rv2525c are separated by 519 nucleotides Rv2522c: Rv2522c - Conserved hypothetical protein, at 2,838,129 to 2,839,541 Rv2522c Rv2523c: Rv2523c - holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrier protein]pantetheinephosphotransferase), at 2,839,538 to 2,839,930 Rv2523c Rv2524c: Rv2524c - Probable fatty acid synthase Fas (fatty acid synthetase), at 2,840,123 to 2,849,332 Rv2524c Rv2525c: Rv2525c - Conserved hypothetical protein. Secreted; predicted to be a substrate of the twin arginine translocation (tat) export system., at 2,849,852 to 2,850,574 Rv2525c Position (kb) 2840 2841 2842 2843 2844 2845 2846 2847 2848 2849 2850Strain fitness (log2 ratio) -2 -1 0 1at 2839.144 kb on + strand, within Rv2522cat 2839.144 kb on + strand, within Rv2522cat 2839.231 kb on + strand, within Rv2522cat 2839.232 kb on - strand, within Rv2522cat 2839.944 kb on - strandat 2840.059 kb on - strandat 2840.059 kb on - strandat 2840.134 kb on - strandat 2840.134 kb on - strandat 2849.348 kb on - strandat 2849.562 kb on - strandat 2849.964 kb on + strand, within Rv2525cat 2849.964 kb on + strand, within Rv2525cat 2849.964 kb on + strand, within Rv2525cat 2849.964 kb on + strand, within Rv2525cat 2849.965 kb on - strand, within Rv2525cat 2850.051 kb on + strand, within Rv2525cat 2850.052 kb on - strand, within Rv2525cat 2850.052 kb on - strand, within Rv2525cat 2850.099 kb on + strand, within Rv2525cat 2850.120 kb on + strand, within Rv2525cat 2850.120 kb on + strand, within Rv2525cat 2850.120 kb on + strand, within Rv2525cat 2850.120 kb on + strand, within Rv2525cat 2850.120 kb on + strand, within Rv2525cat 2850.121 kb on - strand, within Rv2525cat 2850.121 kb on - strand, within Rv2525cat 2850.129 kb on + strand, within Rv2525cat 2850.130 kb on - strand, within Rv2525cat 2850.130 kb on - strand, within Rv2525cat 2850.130 kb on - strand, within Rv2525cat 2850.271 kb on - strand, within Rv2525cat 2850.276 kb on + strand, within Rv2525cat 2850.277 kb on - strand, within Rv2525c

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Per-strain Table

Position Strand Gene LocusTag Fraction no stress control
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2,839,144 + Rv2522c 0.72 +0.1
2,839,144 + Rv2522c 0.72 +0.0
2,839,231 + Rv2522c 0.78 -0.2
2,839,232 - Rv2522c 0.78 -0.3
2,839,944 - -0.5
2,840,059 - -1.6
2,840,059 - +0.0
2,840,134 - -2.5
2,840,134 - +0.2
2,849,348 - +0.3
2,849,562 - -0.5
2,849,964 + Rv2525c 0.15 +0.7
2,849,964 + Rv2525c 0.15 -0.6
2,849,964 + Rv2525c 0.15 +0.1
2,849,964 + Rv2525c 0.15 -0.2
2,849,965 - Rv2525c 0.16 -0.1
2,850,051 + Rv2525c 0.28 -2.1
2,850,052 - Rv2525c 0.28 +0.2
2,850,052 - Rv2525c 0.28 +1.1
2,850,099 + Rv2525c 0.34 +0.0
2,850,120 + Rv2525c 0.37 -0.0
2,850,120 + Rv2525c 0.37 +0.3
2,850,120 + Rv2525c 0.37 -0.4
2,850,120 + Rv2525c 0.37 -0.8
2,850,120 + Rv2525c 0.37 -0.1
2,850,121 - Rv2525c 0.37 -0.1
2,850,121 - Rv2525c 0.37 +0.3
2,850,129 + Rv2525c 0.38 -1.1
2,850,130 - Rv2525c 0.38 +0.1
2,850,130 - Rv2525c 0.38 -0.3
2,850,130 - Rv2525c 0.38 -0.0
2,850,271 - Rv2525c 0.58 -0.4
2,850,276 + Rv2525c 0.59 +0.1
2,850,277 - Rv2525c 0.59 -0.0

Or see this region's nucleotide sequence