Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2523c

Experiment: no stress control

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2522c and Rv2523c overlap by 4 nucleotidesRv2523c and Rv2524c are separated by 192 nucleotides Rv2522c: Rv2522c - Conserved hypothetical protein, at 2,838,129 to 2,839,541 Rv2522c Rv2523c: Rv2523c - holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrier protein]pantetheinephosphotransferase), at 2,839,538 to 2,839,930 Rv2523c Rv2524c: Rv2524c - Probable fatty acid synthase Fas (fatty acid synthetase), at 2,840,123 to 2,849,332 Rv2524c Position (kb) 2839 2840Strain fitness (log2 ratio) -2 -1 0 1at 2838.543 kb on - strand, within Rv2522cat 2838.543 kb on - strand, within Rv2522cat 2838.615 kb on + strand, within Rv2522cat 2839.144 kb on + strand, within Rv2522cat 2839.144 kb on + strand, within Rv2522cat 2839.231 kb on + strand, within Rv2522cat 2839.232 kb on - strand, within Rv2522cat 2839.944 kb on - strandat 2840.059 kb on - strandat 2840.134 kb on - strandat 2840.134 kb on - strand

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Per-strain Table

Position Strand Gene LocusTag Fraction no stress control
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2,838,543 - Rv2522c 0.29 -1.5
2,838,543 - Rv2522c 0.29 -0.3
2,838,615 + Rv2522c 0.34 -0.5
2,839,144 + Rv2522c 0.72 +0.1
2,839,144 + Rv2522c 0.72 +0.0
2,839,231 + Rv2522c 0.78 -0.2
2,839,232 - Rv2522c 0.78 -0.3
2,839,944 - -0.5
2,840,059 - -1.6
2,840,134 - -2.5
2,840,134 - +0.2

Or see this region's nucleotide sequence