Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2448c

Experiment: no stress control

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2447c and Rv2448c overlap by 4 nucleotidesRv2448c and Rv2449c are separated by 87 nucleotides Rv2447c: Rv2447c - Probable folylpolyglutamate synthase protein FolC (folylpoly-gamma-glutamate synthetase) (FPGS), at 2,746,135 to 2,747,598 Rv2447c Rv2448c: Rv2448c - Probable valyl-tRNA synthase protein ValS (valyl-tRNA synthetase) (valine--tRNA ligase) (valine translase), at 2,747,595 to 2,750,225 Rv2448c Rv2449c: Rv2449c - Conserved protein, at 2,750,313 to 2,751,572 Rv2449c Position (kb) 2747 2748 2749 2750 2751Strain fitness (log2 ratio) -2 -1 0 1 2at 2750.266 kb on + strandat 2750.266 kb on + strandat 2750.267 kb on - strandat 2750.522 kb on - strand, within Rv2449cat 2750.548 kb on + strand, within Rv2449cat 2750.549 kb on - strand, within Rv2449cat 2750.549 kb on - strand, within Rv2449cat 2750.549 kb on - strand, within Rv2449cat 2750.549 kb on - strand, within Rv2449cat 2750.549 kb on - strand, within Rv2449cat 2750.564 kb on - strand, within Rv2449cat 2750.566 kb on + strand, within Rv2449cat 2750.626 kb on - strand, within Rv2449cat 2750.947 kb on + strand, within Rv2449cat 2750.947 kb on + strand, within Rv2449cat 2750.948 kb on - strand, within Rv2449cat 2750.948 kb on - strand, within Rv2449cat 2750.948 kb on - strand, within Rv2449cat 2750.958 kb on + strand, within Rv2449cat 2750.959 kb on - strand, within Rv2449cat 2750.985 kb on - strand, within Rv2449cat 2751.109 kb on + strand, within Rv2449cat 2751.112 kb on - strand, within Rv2449cat 2751.112 kb on - strand, within Rv2449cat 2751.118 kb on + strand, within Rv2449cat 2751.119 kb on - strand, within Rv2449cat 2751.119 kb on - strand, within Rv2449cat 2751.200 kb on - strand, within Rv2449c

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Per-strain Table

Position Strand Gene LocusTag Fraction no stress control
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2,750,266 + -0.5
2,750,266 + -0.5
2,750,267 - -0.2
2,750,522 - Rv2449c 0.17 +0.0
2,750,548 + Rv2449c 0.19 +0.2
2,750,549 - Rv2449c 0.19 -0.3
2,750,549 - Rv2449c 0.19 -2.2
2,750,549 - Rv2449c 0.19 -1.4
2,750,549 - Rv2449c 0.19 -0.0
2,750,549 - Rv2449c 0.19 -0.2
2,750,564 - Rv2449c 0.20 -0.5
2,750,566 + Rv2449c 0.20 -0.4
2,750,626 - Rv2449c 0.25 +0.3
2,750,947 + Rv2449c 0.50 +0.1
2,750,947 + Rv2449c 0.50 -0.2
2,750,948 - Rv2449c 0.50 +1.8
2,750,948 - Rv2449c 0.50 +0.2
2,750,948 - Rv2449c 0.50 +1.0
2,750,958 + Rv2449c 0.51 -0.1
2,750,959 - Rv2449c 0.51 -0.1
2,750,985 - Rv2449c 0.53 +0.4
2,751,109 + Rv2449c 0.63 -1.0
2,751,112 - Rv2449c 0.63 -0.8
2,751,112 - Rv2449c 0.63 -1.9
2,751,118 + Rv2449c 0.64 +0.4
2,751,119 - Rv2449c 0.64 +0.0
2,751,119 - Rv2449c 0.64 +0.2
2,751,200 - Rv2449c 0.70 +0.6

Or see this region's nucleotide sequence