Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2421c

Experiment: no stress control

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2419c and Rv2420c overlap by 4 nucleotidesRv2420c and Rv2421c overlap by 4 nucleotidesRv2421c and Rv2422 are separated by 274 nucleotidesRv2422 and Rv2423 are separated by 241 nucleotides Rv2419c: Rv2419c - Glucosyl-3-phosphoglycerate phosphatase GpgP, at 2,717,128 to 2,717,799 Rv2419c Rv2420c: Rv2420c - Conserved hypothetical protein, at 2,717,796 to 2,718,176 Rv2420c Rv2421c: Rv2421c - Probable nicotinate-nucleotide adenylyltransferase NadD (deamido-NAD(+) pyrophosphorylase) (deamido-NAD(+) diphosphorylase) (nicotinate mononucleotide adenylyltransferase) (NAMN adenylyltransferase), at 2,718,173 to 2,718,808 Rv2421c Rv2422: Rv2422 - Hypothetical protein, at 2,719,083 to 2,719,355 Rv2422 Rv2423: Rv2423 - Hypothetical protein, at 2,719,597 to 2,720,643 Rv2423 Position (kb) 2718 2719Strain fitness (log2 ratio) -1 0 1 2at 2717.616 kb on - strand, within Rv2419cat 2717.754 kb on - strandat 2717.754 kb on - strandat 2718.846 kb on - strandat 2718.853 kb on + strandat 2718.854 kb on - strandat 2718.937 kb on - strandat 2718.937 kb on - strandat 2719.052 kb on + strandat 2719.053 kb on - strandat 2719.166 kb on + strand, within Rv2422at 2719.167 kb on - strand, within Rv2422at 2719.181 kb on - strand, within Rv2422at 2719.559 kb on + strandat 2719.560 kb on - strandat 2719.573 kb on + strandat 2719.574 kb on - strandat 2719.585 kb on + strandat 2719.585 kb on + strandat 2719.585 kb on + strandat 2719.585 kb on + strandat 2719.586 kb on - strandat 2719.586 kb on - strandat 2719.586 kb on - strandat 2719.666 kb on + strandat 2719.667 kb on - strandat 2719.730 kb on - strand, within Rv2423at 2719.730 kb on - strand, within Rv2423at 2719.730 kb on - strand, within Rv2423

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Per-strain Table

Position Strand Gene LocusTag Fraction no stress control
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2,717,616 - Rv2419c 0.73 +1.8
2,717,754 - -0.9
2,717,754 - -0.0
2,718,846 - -0.3
2,718,853 + -0.5
2,718,854 - -0.4
2,718,937 - -0.5
2,718,937 - +0.8
2,719,052 + -0.4
2,719,053 - -0.1
2,719,166 + Rv2422 0.30 +0.2
2,719,167 - Rv2422 0.31 -0.3
2,719,181 - Rv2422 0.36 -0.3
2,719,559 + +0.1
2,719,560 - +0.1
2,719,573 + +0.5
2,719,574 - +0.8
2,719,585 + +1.8
2,719,585 + -0.2
2,719,585 + -0.5
2,719,585 + +0.5
2,719,586 - -0.7
2,719,586 - +0.8
2,719,586 - -0.4
2,719,666 + -0.0
2,719,667 - +0.4
2,719,730 - Rv2423 0.13 -0.4
2,719,730 - Rv2423 0.13 +0.2
2,719,730 - Rv2423 0.13 -0.1

Or see this region's nucleotide sequence