Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2401

Experiment: no stress control

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2400c and Rv2401 are separated by 13 nucleotidesRv2401 and Rv2401A overlap by 16 nucleotidesRv2401A and Rv2402 are separated by 283 nucleotides Rv2400c: Rv2400c - Probable sulfate-binding lipoprotein SubI, at 2,696,644 to 2,697,714 Rv2400c Rv2401: Rv2401 - Hypothetical protein, at 2,697,728 to 2,698,057 Rv2401 Rv2401A: Rv2401A - Possible conserved membrane protein, at 2,698,042 to 2,698,245 Rv2401A Rv2402: Rv2402 - Conserved protein, at 2,698,529 to 2,700,457 Rv2402 Position (kb) 2697 2698 2699Strain fitness (log2 ratio) -1 0 1 2at 2697.090 kb on + strand, within Rv2400cat 2697.651 kb on + strandat 2698.043 kb on + strandat 2698.248 kb on + strandat 2698.248 kb on + strandat 2698.249 kb on - strandat 2698.287 kb on - strandat 2698.287 kb on - strandat 2698.330 kb on + strandat 2698.331 kb on - strandat 2698.536 kb on + strandat 2698.840 kb on + strand, within Rv2402at 2698.840 kb on + strand, within Rv2402at 2698.983 kb on - strand, within Rv2402at 2699.025 kb on - strand, within Rv2402at 2699.038 kb on - strand, within Rv2402at 2699.038 kb on - strand, within Rv2402at 2699.038 kb on - strand, within Rv2402

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Per-strain Table

Position Strand Gene LocusTag Fraction no stress control
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2,697,090 + Rv2400c 0.42 +0.5
2,697,651 + +1.5
2,698,043 + +0.2
2,698,248 + -0.4
2,698,248 + +0.8
2,698,249 - -0.2
2,698,287 - -0.3
2,698,287 - -0.5
2,698,330 + -0.5
2,698,331 - -1.2
2,698,536 + -0.9
2,698,840 + Rv2402 0.16 -0.1
2,698,840 + Rv2402 0.16 +1.8
2,698,983 - Rv2402 0.24 +0.4
2,699,025 - Rv2402 0.26 -0.4
2,699,038 - Rv2402 0.26 -1.0
2,699,038 - Rv2402 0.26 -0.4
2,699,038 - Rv2402 0.26 -0.6

Or see this region's nucleotide sequence