Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2393

Experiment: no stress control

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2391 and Rv2392 overlap by 4 nucleotidesRv2392 and Rv2393 overlap by 4 nucleotidesRv2393 and Rv2394 are separated by 36 nucleotides Rv2391: Rv2391 - Ferredoxin-dependent sulfite reductase SirA, at 2,684,679 to 2,686,370 Rv2391 Rv2392: Rv2392 - Probable 3'-phosphoadenosine 5'-phosphosulfate reductase CysH (PAPS reductase, thioredoxin DEP.) (padops reductase) (3'-phosphoadenylylsulfate reductase) (PAPS sulfotransferase), at 2,686,367 to 2,687,131 Rv2392 Rv2393: Rv2393 - Ferrochelatase Che1, at 2,687,128 to 2,687,973 Rv2393 Rv2394: Rv2394 - Probable gamma-glutamyltranspeptidase precursor GgtB (gamma-glutamyltransferase) (glutamyl transpeptidase), at 2,688,010 to 2,689,941 Rv2394 Position (kb) 2687 2688Strain fitness (log2 ratio) -1 0 1at 2687.971 kb on + strandat 2688.248 kb on - strand, within Rv2394at 2688.297 kb on - strand, within Rv2394at 2688.394 kb on + strand, within Rv2394at 2688.403 kb on + strand, within Rv2394at 2688.403 kb on + strand, within Rv2394at 2688.403 kb on + strand, within Rv2394at 2688.404 kb on - strand, within Rv2394at 2688.478 kb on + strand, within Rv2394at 2688.478 kb on + strand, within Rv2394at 2688.479 kb on - strand, within Rv2394at 2688.479 kb on - strand, within Rv2394at 2688.734 kb on - strand, within Rv2394at 2688.734 kb on - strand, within Rv2394

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Per-strain Table

Position Strand Gene LocusTag Fraction no stress control
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2,687,971 + -0.3
2,688,248 - Rv2394 0.12 +0.3
2,688,297 - Rv2394 0.15 +0.5
2,688,394 + Rv2394 0.20 -1.2
2,688,403 + Rv2394 0.20 -0.4
2,688,403 + Rv2394 0.20 +0.8
2,688,403 + Rv2394 0.20 -0.6
2,688,404 - Rv2394 0.20 -0.9
2,688,478 + Rv2394 0.24 -0.1
2,688,478 + Rv2394 0.24 -0.4
2,688,479 - Rv2394 0.24 -0.4
2,688,479 - Rv2394 0.24 -0.6
2,688,734 - Rv2394 0.37 -0.4
2,688,734 - Rv2394 0.37 -0.5

Or see this region's nucleotide sequence