Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2359

Experiment: no stress control

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2357c and Rv2358 are separated by 181 nucleotidesRv2358 and Rv2359 overlap by 4 nucleotidesRv2359 and Rv2360c are separated by 107 nucleotidesRv2360c and Rv2361c overlap by 1 nucleotides Rv2357c: Rv2357c - Probable glycyl-tRNA synthetase GlyS (glycine--tRNA ligase) (GLYRS), at 2,639,673 to 2,641,064 Rv2357c Rv2358: Rv2358 - Probable transcriptional regulatory protein SmtB (probably ArsR-family), at 2,641,246 to 2,641,653 Rv2358 Rv2359: Rv2359 - Probable zinc uptake regulation protein Zur, at 2,641,650 to 2,642,042 Rv2359 Rv2360c: Rv2360c - Unknown protein, at 2,642,150 to 2,642,578 Rv2360c Rv2361c: Rv2361c - Long (C50) chain Z-isoprenyl diphosphate synthase (Z-decaprenyl diphosphate synthase), at 2,642,578 to 2,643,468 Rv2361c Position (kb) 2641 2642 2643Strain fitness (log2 ratio) -2 -1 0 1at 2641.154 kb on - strandat 2641.213 kb on + strandat 2641.213 kb on + strandat 2641.213 kb on + strandat 2641.216 kb on + strandat 2641.245 kb on + strandat 2641.245 kb on + strandat 2641.304 kb on + strand, within Rv2358at 2641.304 kb on + strand, within Rv2358at 2641.379 kb on + strand, within Rv2358at 2642.483 kb on - strand, within Rv2360cat 2642.483 kb on - strand, within Rv2360cat 2642.579 kb on + strand

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Per-strain Table

Position Strand Gene LocusTag Fraction no stress control
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2,641,154 - -0.9
2,641,213 + +0.3
2,641,213 + +0.6
2,641,213 + -0.6
2,641,216 + -0.3
2,641,245 + -0.2
2,641,245 + -1.9
2,641,304 + Rv2358 0.14 +0.3
2,641,304 + Rv2358 0.14 +0.0
2,641,379 + Rv2358 0.33 -0.0
2,642,483 - Rv2360c 0.78 -1.0
2,642,483 - Rv2360c 0.78 -0.2
2,642,579 + -1.2

Or see this region's nucleotide sequence