Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2278

Experiment: no stress control

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2277c and Rv2278 are separated by 35 nucleotidesRv2278 and Rv2279 overlap by 52 nucleotides Rv2277c: Rv2277c - Possible glycerolphosphodiesterase, at 2,549,124 to 2,550,029 Rv2277c Rv2278: Rv2278 - Putative transposase for insertion sequence element IS6110 (fragment), at 2,550,065 to 2,550,391 Rv2278 Rv2279: Rv2279 - Probable transposase, at 2,550,340 to 2,551,326 Rv2279 Position (kb) 2550 2551Strain fitness (log2 ratio) -1 0 1 2at 2549.512 kb on - strand, within Rv2277cat 2549.598 kb on + strand, within Rv2277cat 2549.598 kb on + strand, within Rv2277cat 2549.800 kb on + strand, within Rv2277cat 2549.877 kb on - strand, within Rv2277cat 2551.381 kb on + strandat 2551.381 kb on + strand

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Per-strain Table

Position Strand Gene LocusTag Fraction no stress control
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2,549,512 - Rv2277c 0.43 +0.3
2,549,598 + Rv2277c 0.52 +0.1
2,549,598 + Rv2277c 0.52 +0.2
2,549,800 + Rv2277c 0.75 -0.9
2,549,877 - Rv2277c 0.83 +0.5
2,551,381 + -0.5
2,551,381 + +1.8

Or see this region's nucleotide sequence