Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2241

Experiment: no stress control

Add experiment(s):

Zoom: Pan:

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

download SVG
500 ntRv2239c and Rv2240c are separated by 37 nucleotidesRv2240c and Rv2241 are separated by 258 nucleotidesRv2241 and Rv2242 are separated by 59 nucleotides Rv2239c: Rv2239c - Conserved hypothetical protein, at 2,511,176 to 2,511,652 Rv2239c Rv2240c: Rv2240c - Unknown protein, at 2,511,690 to 2,512,280 Rv2240c Rv2241: Rv2241 - Pyruvate dehydrogenase E1 component AceE (pyruvate decarboxylase) (pyruvate dehydrogenase) (pyruvic dehydrogenase), at 2,512,539 to 2,515,244 Rv2241 Rv2242: Rv2242 - Conserved hypothetical protein, at 2,515,304 to 2,516,548 Rv2242 Position (kb) 2512 2513 2514 2515 2516Strain fitness (log2 ratio) -2 -1 0 1 2at 2511.820 kb on + strand, within Rv2240cat 2511.820 kb on + strand, within Rv2240cat 2511.821 kb on - strand, within Rv2240cat 2512.407 kb on + strandat 2512.407 kb on + strandat 2512.407 kb on + strandat 2513.868 kb on + strand, within Rv2241at 2514.348 kb on + strand, within Rv2241at 2515.242 kb on + strand

download strain data

Per-strain Table

Position Strand Gene LocusTag Fraction no stress control
remove
2,511,820 + Rv2240c 0.22 -1.4
2,511,820 + Rv2240c 0.22 -0.4
2,511,821 - Rv2240c 0.22 -1.9
2,512,407 + -0.9
2,512,407 + -0.2
2,512,407 + -0.8
2,513,868 + Rv2241 0.49 +1.8
2,514,348 + Rv2241 0.67 -1.8
2,515,242 + +0.0

Or see this region's nucleotide sequence