Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2188c

Experiment: no stress control

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2187 and Rv2188c are separated by 30 nucleotidesRv2188c and Rv2189c are separated by 96 nucleotidesRv2189c and Rv2190c are separated by 94 nucleotides Rv2187: Rv2187 - Long-chain-fatty-acid-CoA ligase FadD15 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase), at 2,448,160 to 2,449,962 Rv2187 Rv2188c: Rv2188c - Mannosyltransferase PimB, at 2,449,993 to 2,451,150 Rv2188c Rv2189c: Rv2189c - Conserved hypothetical protein, at 2,451,247 to 2,452,020 Rv2189c Rv2190c: Rv2190c - Conserved hypothetical protein, at 2,452,115 to 2,453,272 Rv2190c Position (kb) 2449 2450 2451 2452Strain fitness (log2 ratio) -1 0 1at 2449.009 kb on + strand, within Rv2187at 2449.010 kb on - strand, within Rv2187at 2449.010 kb on - strand, within Rv2187at 2449.163 kb on - strand, within Rv2187at 2449.250 kb on - strand, within Rv2187at 2449.273 kb on + strand, within Rv2187at 2449.274 kb on - strand, within Rv2187at 2449.376 kb on + strand, within Rv2187at 2449.421 kb on + strand, within Rv2187at 2449.422 kb on - strand, within Rv2187at 2449.433 kb on - strand, within Rv2187at 2449.948 kb on + strandat 2449.948 kb on + strandat 2451.249 kb on - strandat 2451.256 kb on + strandat 2451.257 kb on - strandat 2451.381 kb on + strand, within Rv2189cat 2451.386 kb on + strand, within Rv2189cat 2451.387 kb on - strand, within Rv2189cat 2451.428 kb on + strand, within Rv2189cat 2452.026 kb on + strandat 2452.027 kb on - strand

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Per-strain Table

Position Strand Gene LocusTag Fraction no stress control
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2,449,009 + Rv2187 0.47 +1.4
2,449,010 - Rv2187 0.47 -0.2
2,449,010 - Rv2187 0.47 +0.4
2,449,163 - Rv2187 0.56 +0.0
2,449,250 - Rv2187 0.60 -0.2
2,449,273 + Rv2187 0.62 +0.2
2,449,274 - Rv2187 0.62 -0.7
2,449,376 + Rv2187 0.67 -0.3
2,449,421 + Rv2187 0.70 -0.1
2,449,422 - Rv2187 0.70 -0.3
2,449,433 - Rv2187 0.71 +0.0
2,449,948 + -0.9
2,449,948 + -0.3
2,451,249 - +0.5
2,451,256 + -0.2
2,451,257 - +0.8
2,451,381 + Rv2189c 0.17 +0.1
2,451,386 + Rv2189c 0.18 -0.0
2,451,387 - Rv2189c 0.18 -0.2
2,451,428 + Rv2189c 0.23 -0.1
2,452,026 + +0.5
2,452,027 - -0.6

Or see this region's nucleotide sequence