Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2160A

Experiment: no stress control

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2159c and Rv2160A overlap by 23 nucleotidesRv2160A and Rv2160c overlap by 617 nucleotidesRv2160c and Rv2161c are separated by 267 nucleotidesRv2161c and Rv2162c are separated by 102 nucleotides Rv2159c: Rv2159c - Conserved protein, at 2,420,631 to 2,421,665 Rv2159c Rv2160A: Rv2160A - Conserved hypothetical protein, at 2,421,643 to 2,422,278 Rv2160A Rv2160c: Rv2160c - Conserved hypothetical protein, at 2,421,662 to 2,422,003 Rv2160c Rv2161c: Rv2161c - Conserved protein, at 2,422,271 to 2,423,137 Rv2161c Rv2162c: Rv2162c - PE-PGRS family protein PE_PGRS38, at 2,423,240 to 2,424,838 Rv2162c Position (kb) 2421 2422 2423Strain fitness (log2 ratio) -2 -1 0 1 2at 2421.006 kb on + strand, within Rv2159cat 2421.006 kb on + strand, within Rv2159cat 2421.007 kb on - strand, within Rv2159cat 2421.311 kb on - strand, within Rv2159cat 2421.311 kb on - strand, within Rv2159cat 2421.311 kb on - strand, within Rv2159cat 2421.311 kb on - strand, within Rv2159cat 2421.311 kb on - strand, within Rv2159cat 2421.388 kb on + strand, within Rv2159cat 2421.598 kb on + strandat 2421.599 kb on - strandat 2421.992 kb on + strandat 2422.447 kb on - strand, within Rv2161cat 2422.447 kb on - strand, within Rv2161cat 2422.680 kb on + strand, within Rv2161cat 2422.959 kb on + strand, within Rv2161cat 2422.960 kb on - strand, within Rv2161cat 2422.972 kb on - strand, within Rv2161cat 2423.043 kb on + strand, within Rv2161cat 2423.043 kb on + strand, within Rv2161cat 2423.043 kb on + strand, within Rv2161cat 2423.043 kb on + strand, within Rv2161cat 2423.043 kb on + strand, within Rv2161cat 2423.043 kb on + strand, within Rv2161cat 2423.043 kb on + strand, within Rv2161cat 2423.043 kb on + strand, within Rv2161cat 2423.044 kb on - strand, within Rv2161cat 2423.044 kb on - strand, within Rv2161cat 2423.044 kb on - strand, within Rv2161cat 2423.044 kb on - strand, within Rv2161cat 2423.044 kb on - strand, within Rv2161cat 2423.044 kb on - strand, within Rv2161cat 2423.044 kb on - strand, within Rv2161cat 2423.044 kb on - strand, within Rv2161cat 2423.154 kb on + strandat 2423.154 kb on + strandat 2423.155 kb on - strandat 2423.155 kb on - strandat 2423.155 kb on - strandat 2423.155 kb on - strand

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Per-strain Table

Position Strand Gene LocusTag Fraction no stress control
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2,421,006 + Rv2159c 0.36 +0.2
2,421,006 + Rv2159c 0.36 -0.1
2,421,007 - Rv2159c 0.36 +0.2
2,421,311 - Rv2159c 0.66 -0.7
2,421,311 - Rv2159c 0.66 +1.5
2,421,311 - Rv2159c 0.66 -0.6
2,421,311 - Rv2159c 0.66 -0.6
2,421,311 - Rv2159c 0.66 -0.2
2,421,388 + Rv2159c 0.73 -0.2
2,421,598 + -2.0
2,421,599 - -1.2
2,421,992 + -1.0
2,422,447 - Rv2161c 0.20 +2.4
2,422,447 - Rv2161c 0.20 +0.1
2,422,680 + Rv2161c 0.47 +1.1
2,422,959 + Rv2161c 0.79 -0.1
2,422,960 - Rv2161c 0.79 -1.1
2,422,972 - Rv2161c 0.81 -0.8
2,423,043 + Rv2161c 0.89 -0.8
2,423,043 + Rv2161c 0.89 -0.7
2,423,043 + Rv2161c 0.89 -0.9
2,423,043 + Rv2161c 0.89 +1.1
2,423,043 + Rv2161c 0.89 +0.2
2,423,043 + Rv2161c 0.89 -0.2
2,423,043 + Rv2161c 0.89 -0.7
2,423,043 + Rv2161c 0.89 -0.5
2,423,044 - Rv2161c 0.89 -0.9
2,423,044 - Rv2161c 0.89 -0.3
2,423,044 - Rv2161c 0.89 -0.4
2,423,044 - Rv2161c 0.89 -1.1
2,423,044 - Rv2161c 0.89 +1.4
2,423,044 - Rv2161c 0.89 -0.7
2,423,044 - Rv2161c 0.89 -0.4
2,423,044 - Rv2161c 0.89 -0.0
2,423,154 + -1.2
2,423,154 + +0.1
2,423,155 - +0.2
2,423,155 - -0.4
2,423,155 - -0.2
2,423,155 - +1.4

Or see this region's nucleotide sequence