Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2122c

Experiment: no stress control

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2120c and Rv2121c are separated by 78 nucleotidesRv2121c and Rv2122c are separated by 2 nucleotidesRv2122c and Rv2123 are separated by 126 nucleotides Rv2120c: Rv2120c - Probable conserved integral membrane protein, at 2,379,245 to 2,379,727 Rv2120c Rv2121c: Rv2121c - ATP phosphoribosyltransferase HisG, at 2,379,806 to 2,380,660 Rv2121c Rv2122c: Rv2122c - Phosphoribosyl-AMP pyrophosphatase HisE, at 2,380,663 to 2,380,944 Rv2122c Rv2123: Rv2123 - PPE family protein PPE37, at 2,381,071 to 2,382,492 Rv2123 Position (kb) 2380 2381Strain fitness (log2 ratio) -1 0 1at 2381.307 kb on - strand, within Rv2123at 2381.368 kb on + strand, within Rv2123at 2381.370 kb on + strand, within Rv2123at 2381.370 kb on + strand, within Rv2123at 2381.370 kb on + strand, within Rv2123at 2381.370 kb on + strand, within Rv2123at 2381.370 kb on + strand, within Rv2123at 2381.394 kb on + strand, within Rv2123at 2381.394 kb on + strand, within Rv2123at 2381.394 kb on + strand, within Rv2123at 2381.395 kb on - strand, within Rv2123at 2381.395 kb on - strand, within Rv2123at 2381.498 kb on - strand, within Rv2123at 2381.698 kb on + strand, within Rv2123at 2381.803 kb on + strand, within Rv2123at 2381.827 kb on + strand, within Rv2123

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Per-strain Table

Position Strand Gene LocusTag Fraction no stress control
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2,381,307 - Rv2123 0.17 -0.2
2,381,368 + Rv2123 0.21 -1.3
2,381,370 + Rv2123 0.21 -0.6
2,381,370 + Rv2123 0.21 -0.1
2,381,370 + Rv2123 0.21 -0.6
2,381,370 + Rv2123 0.21 -1.7
2,381,370 + Rv2123 0.21 +0.3
2,381,394 + Rv2123 0.23 -0.5
2,381,394 + Rv2123 0.23 -0.6
2,381,394 + Rv2123 0.23 -0.4
2,381,395 - Rv2123 0.23 +0.9
2,381,395 - Rv2123 0.23 -0.0
2,381,498 - Rv2123 0.30 +0.0
2,381,698 + Rv2123 0.44 +0.7
2,381,803 + Rv2123 0.51 +0.1
2,381,827 + Rv2123 0.53 -1.0

Or see this region's nucleotide sequence