Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2106

Experiment: no stress control

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2104c and Rv2105 are separated by 683 nucleotidesRv2105 and Rv2106 overlap by 52 nucleotidesRv2106 and Rv2107 are separated by 632 nucleotidesRv2107 and Rv2108 are separated by 55 nucleotides Rv2104c: Rv2104c - Possible antitoxin VapB37, at 2,364,527 to 2,364,781 Rv2104c Rv2105: Rv2105 - Putative transposase for insertion sequence element IS6110 (fragment), at 2,365,465 to 2,365,791 Rv2105 Rv2106: Rv2106 - Probable transposase, at 2,365,740 to 2,366,726 Rv2106 Rv2107: Rv2107 - PE family protein PE22, at 2,367,359 to 2,367,655 Rv2107 Rv2108: Rv2108 - PPE family protein PPE36, at 2,367,711 to 2,368,442 Rv2108 Position (kb) 2365 2366 2367Strain fitness (log2 ratio) -2 -1 0 1at 2364.845 kb on - strandat 2365.132 kb on + strandat 2365.133 kb on - strandat 2365.300 kb on - strandat 2365.309 kb on - strandat 2365.380 kb on - strandat 2365.384 kb on - strandat 2365.389 kb on + strandat 2365.389 kb on + strandat 2365.390 kb on - strandat 2366.973 kb on - strandat 2366.975 kb on + strandat 2367.061 kb on - strandat 2367.112 kb on + strandat 2367.261 kb on - strandat 2367.321 kb on + strandat 2367.322 kb on - strandat 2367.375 kb on + strandat 2367.494 kb on + strand, within Rv2107at 2367.617 kb on + strand, within Rv2107at 2367.669 kb on - strandat 2367.710 kb on + strand

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Per-strain Table

Position Strand Gene LocusTag Fraction no stress control
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2,364,845 - +0.7
2,365,132 + -0.5
2,365,133 - -1.0
2,365,300 - +0.1
2,365,309 - +0.1
2,365,380 - -0.7
2,365,384 - -0.4
2,365,389 + -0.1
2,365,389 + -0.5
2,365,390 - -0.2
2,366,973 - -0.2
2,366,975 + -0.6
2,367,061 - -1.9
2,367,112 + -0.1
2,367,261 - -0.9
2,367,321 + -0.6
2,367,322 - +0.1
2,367,375 + -0.1
2,367,494 + Rv2107 0.45 -1.0
2,367,617 + Rv2107 0.87 -0.8
2,367,669 - -0.1
2,367,710 + -2.2

Or see this region's nucleotide sequence