Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1794

Experiment: no stress control

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1791 and Rv1792 are separated by 143 nucleotidesRv1792 and Rv1793 are separated by 50 nucleotidesRv1793 and Rv1794 are separated by 87 nucleotidesRv1794 and Rv1795 are separated by 271 nucleotides Rv1791: Rv1791 - PE family protein PE19, at 2,029,904 to 2,030,203 Rv1791 Rv1792: Rv1792 - ESAT-6 like protein EsxM, at 2,030,347 to 2,030,643 Rv1792 Rv1793: Rv1793 - Putative ESAT-6 like protein EsxN (ESAT-6 like protein 5), at 2,030,694 to 2,030,978 Rv1793 Rv1794: Rv1794 - Conserved protein, at 2,031,066 to 2,031,968 Rv1794 Rv1795: Rv1795 - ESX conserved component EccD5. ESX-5 type VII secretion system protein. Probable membrane protein., at 2,032,240 to 2,033,751 Rv1795 Position (kb) 2031 2032Strain fitness (log2 ratio) -1 0 1at 2030.087 kb on + strand, within Rv1791at 2030.302 kb on + strandat 2030.302 kb on + strandat 2030.328 kb on + strandat 2030.329 kb on - strandat 2030.329 kb on - strandat 2030.329 kb on - strandat 2030.332 kb on - strandat 2030.332 kb on - strandat 2030.599 kb on + strand, within Rv1792at 2030.641 kb on + strandat 2030.693 kb on + strandat 2030.693 kb on + strandat 2030.693 kb on + strandat 2030.702 kb on + strandat 2030.702 kb on + strandat 2031.042 kb on + strandat 2031.061 kb on + strandat 2032.207 kb on + strandat 2032.207 kb on + strand

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Per-strain Table

Position Strand Gene LocusTag Fraction no stress control
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2,030,087 + Rv1791 0.61 -0.3
2,030,302 + +0.4
2,030,302 + -0.8
2,030,328 + +0.5
2,030,329 - +0.0
2,030,329 - +0.3
2,030,329 - -0.4
2,030,332 - -0.1
2,030,332 - +0.1
2,030,599 + Rv1792 0.85 -0.1
2,030,641 + -0.8
2,030,693 + -0.1
2,030,693 + -0.4
2,030,693 + +0.3
2,030,702 + -0.5
2,030,702 + +0.1
2,031,042 + +0.8
2,031,061 + -0.5
2,032,207 + -0.0
2,032,207 + -1.0

Or see this region's nucleotide sequence