Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1603

Experiment: no stress control

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1601 and Rv1602 overlap by 4 nucleotidesRv1602 and Rv1603 are separated by 9 nucleotidesRv1603 and Rv1604 are separated by 7 nucleotidesRv1604 and Rv1605 are separated by 1 nucleotides Rv1601: Rv1601 - Probable imidazole glycerol-phosphate dehydratase HisB, at 1,802,035 to 1,802,667 Rv1601 Rv1602: Rv1602 - Probable amidotransferase HisH, at 1,802,664 to 1,803,284 Rv1602 Rv1603: Rv1603 - Probable phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase HisA, at 1,803,294 to 1,804,031 Rv1603 Rv1604: Rv1604 - Probable inositol-monophosphatase ImpA (imp), at 1,804,039 to 1,804,851 Rv1604 Rv1605: Rv1605 - Probable cyclase HisF, at 1,804,853 to 1,805,656 Rv1605 Position (kb) 1803 1804 1805Strain fitness (log2 ratio) -2 -1 0 1at 1803.307 kb on + strandat 1804.414 kb on + strand, within Rv1604at 1804.830 kb on - strandat 1804.846 kb on + strand

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Per-strain Table

Position Strand Gene LocusTag Fraction no stress control
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1,803,307 + +0.5
1,804,414 + Rv1604 0.46 +0.7
1,804,830 - -2.0
1,804,846 + -0.2

Or see this region's nucleotide sequence