Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1473

Experiment: no stress control

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1471 and Rv1472 are separated by 21 nucleotidesRv1472 and Rv1473 are separated by 35 nucleotidesRv1473 and Rv1473A are separated by 96 nucleotidesRv1473A and Rv1474c are separated by 68 nucleotidesRv1474c and Rv1475c are separated by 10 nucleotides Rv1471: Rv1471 - Probable thioredoxin TrxB1, at 1,659,370 to 1,659,741 Rv1471 Rv1472: Rv1472 - Possible enoyl-CoA hydratase EchA12 (enoyl hydrase) (unsaturated acyl-CoA hydratase) (crotonase), at 1,659,763 to 1,660,620 Rv1472 Rv1473: Rv1473 - Probable macrolide-transport ATP-binding protein ABC transporter, at 1,660,656 to 1,662,284 Rv1473 Rv1473A: Rv1473A - Possible transcriptional regulatory protein, at 1,662,381 to 1,662,572 Rv1473A Rv1474c: Rv1474c - Probable transcriptional regulatory protein, at 1,662,641 to 1,663,204 Rv1474c Rv1475c: Rv1475c - Probable iron-regulated aconitate hydratase Acn (citrate hydro-lyase) (aconitase), at 1,663,215 to 1,666,046 Rv1475c Position (kb) 1660 1661 1662 1663Strain fitness (log2 ratio) -1 0 1at 1659.941 kb on - strand, within Rv1472at 1660.057 kb on + strand, within Rv1472at 1660.057 kb on + strand, within Rv1472at 1660.057 kb on + strand, within Rv1472at 1660.058 kb on - strand, within Rv1472at 1660.058 kb on - strand, within Rv1472at 1660.204 kb on - strand, within Rv1472at 1660.394 kb on + strand, within Rv1472at 1660.464 kb on + strand, within Rv1472at 1660.465 kb on - strand, within Rv1472at 1660.465 kb on - strand, within Rv1472at 1660.465 kb on - strand, within Rv1472at 1660.563 kb on - strandat 1660.618 kb on + strandat 1660.618 kb on + strandat 1660.618 kb on + strandat 1660.668 kb on - strandat 1660.766 kb on + strandat 1660.766 kb on + strandat 1660.822 kb on - strand, within Rv1473at 1661.354 kb on + strand, within Rv1473at 1661.841 kb on + strand, within Rv1473at 1662.288 kb on - strandat 1662.288 kb on - strandat 1662.347 kb on + strandat 1662.347 kb on + strandat 1662.348 kb on - strandat 1662.348 kb on - strandat 1662.353 kb on - strandat 1662.353 kb on - strandat 1662.486 kb on + strand, within Rv1473Aat 1662.494 kb on + strand, within Rv1473Aat 1662.987 kb on - strand, within Rv1474cat 1662.987 kb on - strand, within Rv1474cat 1662.987 kb on - strand, within Rv1474cat 1663.229 kb on + strandat 1663.231 kb on - strand

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Per-strain Table

Position Strand Gene LocusTag Fraction no stress control
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1,659,941 - Rv1472 0.21 +0.0
1,660,057 + Rv1472 0.34 -0.0
1,660,057 + Rv1472 0.34 +0.4
1,660,057 + Rv1472 0.34 -1.4
1,660,058 - Rv1472 0.34 +0.1
1,660,058 - Rv1472 0.34 -1.4
1,660,204 - Rv1472 0.51 -0.4
1,660,394 + Rv1472 0.74 -0.2
1,660,464 + Rv1472 0.82 -1.3
1,660,465 - Rv1472 0.82 +0.5
1,660,465 - Rv1472 0.82 -0.4
1,660,465 - Rv1472 0.82 +0.5
1,660,563 - -1.0
1,660,618 + +0.7
1,660,618 + -0.4
1,660,618 + -0.9
1,660,668 - +0.1
1,660,766 + -0.5
1,660,766 + -0.2
1,660,822 - Rv1473 0.10 -1.4
1,661,354 + Rv1473 0.43 +0.0
1,661,841 + Rv1473 0.73 -0.0
1,662,288 - -1.0
1,662,288 - -1.0
1,662,347 + +0.2
1,662,347 + +0.9
1,662,348 - +0.3
1,662,348 - -0.3
1,662,353 - -1.0
1,662,353 - -0.2
1,662,486 + Rv1473A 0.55 +0.4
1,662,494 + Rv1473A 0.59 +0.8
1,662,987 - Rv1474c 0.61 -0.6
1,662,987 - Rv1474c 0.61 -0.7
1,662,987 - Rv1474c 0.61 +0.9
1,663,229 + +0.5
1,663,231 - +0.2

Or see this region's nucleotide sequence