Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1408

Experiment: no stress control

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1407 and Rv1408 are separated by 24 nucleotidesRv1408 and Rv1409 overlap by 4 nucleotides Rv1407: Rv1407 - Probable Fmu protein (sun protein), at 1,583,101 to 1,584,474 Rv1407 Rv1408: Rv1408 - Probable ribulose-phosphate 3-epimerase Rpe (PPE) (R5P3E) (pentose-5-phosphate 3-epimerase), at 1,584,499 to 1,585,197 Rv1408 Rv1409: Rv1409 - Probable bifunctional riboflavin biosynthesis protein RibG : diaminohydroxyphosphoribosylaminopyrimidine deaminase (riboflavin-specific deaminase) + 5-amino-6-(5-phosphoribosylamino) uracil reductase (HTP reductase), at 1,585,194 to 1,586,213 Rv1409 Position (kb) 1584 1585 1586Strain fitness (log2 ratio) -1 0 1at 1583.786 kb on - strand, within Rv1407at 1583.904 kb on + strand, within Rv1407at 1584.030 kb on - strand, within Rv1407at 1584.149 kb on + strand, within Rv1407at 1584.194 kb on + strand, within Rv1407at 1584.195 kb on - strand, within Rv1407at 1584.195 kb on - strand, within Rv1407at 1584.213 kb on - strand, within Rv1407at 1584.213 kb on - strand, within Rv1407at 1584.271 kb on + strand, within Rv1407at 1584.271 kb on + strand, within Rv1407at 1584.272 kb on - strand, within Rv1407at 1584.272 kb on - strand, within Rv1407at 1584.272 kb on - strand, within Rv1407at 1584.272 kb on - strand, within Rv1407at 1584.495 kb on + strandat 1584.495 kb on + strandat 1584.496 kb on - strand

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Per-strain Table

Position Strand Gene LocusTag Fraction no stress control
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1,583,786 - Rv1407 0.50 -0.2
1,583,904 + Rv1407 0.58 -0.3
1,584,030 - Rv1407 0.68 -0.5
1,584,149 + Rv1407 0.76 -0.6
1,584,194 + Rv1407 0.80 -0.9
1,584,195 - Rv1407 0.80 -0.7
1,584,195 - Rv1407 0.80 +0.2
1,584,213 - Rv1407 0.81 -0.5
1,584,213 - Rv1407 0.81 -0.3
1,584,271 + Rv1407 0.85 -0.0
1,584,271 + Rv1407 0.85 -0.3
1,584,272 - Rv1407 0.85 +0.3
1,584,272 - Rv1407 0.85 -0.1
1,584,272 - Rv1407 0.85 -0.1
1,584,272 - Rv1407 0.85 +0.0
1,584,495 + -0.1
1,584,495 + +0.4
1,584,496 - +0.0

Or see this region's nucleotide sequence