Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1380

Experiment: no stress control

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1378c and Rv1379 overlap by 2 nucleotidesRv1379 and Rv1380 overlap by 4 nucleotidesRv1380 and Rv1381 overlap by 4 nucleotides Rv1378c: Rv1378c - Conserved hypothetical protein, at 1,551,228 to 1,552,655 Rv1378c Rv1379: Rv1379 - Probable pyrimidine operon regulatory protein PyrR, at 1,552,654 to 1,553,235 Rv1379 Rv1380: Rv1380 - Probable aspartate carbamoyltransferase PyrB (ATCase) (aspartate transcarbamylase), at 1,553,232 to 1,554,191 Rv1380 Rv1381: Rv1381 - Probable dihydroorotase PyrC (DHOase), at 1,554,188 to 1,555,480 Rv1381 Position (kb) 1553 1554 1555Strain fitness (log2 ratio) -2 -1 0 1 2at 1552.584 kb on + strandat 1552.584 kb on + strandat 1552.584 kb on + strandat 1553.140 kb on + strand, within Rv1379at 1553.140 kb on + strand, within Rv1379

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Per-strain Table

Position Strand Gene LocusTag Fraction no stress control
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1,552,584 + +0.3
1,552,584 + -0.1
1,552,584 + -1.9
1,553,140 + Rv1379 0.84 -0.1
1,553,140 + Rv1379 0.84 +1.8

Or see this region's nucleotide sequence