Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1339

Experiment: no stress control

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1337 and Rv1338 overlap by 4 nucleotidesRv1338 and Rv1339 are separated by 26 nucleotidesRv1339 and Rv1340 are separated by 16 nucleotidesRv1340 and Rv1341 are separated by 38 nucleotides Rv1337: Rv1337 - Probable integral membrane protein, at 1,504,356 to 1,505,078 Rv1337 Rv1338: Rv1338 - Probable glutamate racemase MurI, at 1,505,075 to 1,505,890 Rv1338 Rv1339: Rv1339 - Conserved protein, at 1,505,917 to 1,506,738 Rv1339 Rv1340: Rv1340 - Probable ribonuclease RphA (RNase PH) (tRNA nucleotidyltransferase), at 1,506,755 to 1,507,534 Rv1340 Rv1341: Rv1341 - Conserved protein, at 1,507,573 to 1,508,187 Rv1341 Position (kb) 1505 1506 1507Strain fitness (log2 ratio) -2 -1 0 1at 1504.969 kb on + strand, within Rv1337at 1504.969 kb on + strand, within Rv1337at 1504.969 kb on + strand, within Rv1337at 1504.969 kb on + strand, within Rv1337at 1504.969 kb on + strand, within Rv1337at 1505.888 kb on + strandat 1505.928 kb on + strandat 1505.943 kb on + strandat 1506.736 kb on + strandat 1506.742 kb on + strandat 1506.743 kb on - strandat 1506.743 kb on - strand

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Per-strain Table

Position Strand Gene LocusTag Fraction no stress control
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1,504,969 + Rv1337 0.85 -1.4
1,504,969 + Rv1337 0.85 -0.1
1,504,969 + Rv1337 0.85 -1.8
1,504,969 + Rv1337 0.85 -0.7
1,504,969 + Rv1337 0.85 -0.2
1,505,888 + +0.4
1,505,928 + -0.7
1,505,943 + -0.8
1,506,736 + -0.0
1,506,742 + +0.6
1,506,743 - +0.8
1,506,743 - -0.1

Or see this region's nucleotide sequence