Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1122

Experiment: no stress control

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1121 and Rv1122 are separated by 21 nucleotidesRv1122 and Rv1123c overlap by 8 nucleotidesRv1123c and Rv1124 are separated by 74 nucleotides Rv1121: Rv1121 - Probable glucose-6-phosphate 1-dehydrogenase Zwf1 (G6PD), at 1,243,707 to 1,245,107 Rv1121 Rv1122: Rv1122 - Probable 6-phosphogluconate dehydrogenase,decarboxylating Gnd2, at 1,245,129 to 1,246,151 Rv1122 Rv1123c: Rv1123c - Possible peroxidase BpoB (non-haem peroxidase), at 1,246,144 to 1,247,052 Rv1123c Rv1124: Rv1124 - Probable epoxide hydrolase EphC (epoxide hydratase), at 1,247,127 to 1,248,077 Rv1124 Position (kb) 1245 1246 1247Strain fitness (log2 ratio) -1 0 1at 1246.150 kb on - strandat 1246.150 kb on - strandat 1246.730 kb on - strand, within Rv1123cat 1246.760 kb on + strand, within Rv1123cat 1246.953 kb on + strand, within Rv1123cat 1246.954 kb on - strand, within Rv1123cat 1247.024 kb on - strandat 1247.088 kb on - strand

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Per-strain Table

Position Strand Gene LocusTag Fraction no stress control
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1,246,150 - -0.6
1,246,150 - -0.7
1,246,730 - Rv1123c 0.64 +0.4
1,246,760 + Rv1123c 0.68 +0.3
1,246,953 + Rv1123c 0.89 -0.8
1,246,954 - Rv1123c 0.89 -0.1
1,247,024 - +0.1
1,247,088 - +0.8

Or see this region's nucleotide sequence