Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1078

Experiment: no stress control

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1077 and Rv1078 are separated by 201 nucleotidesRv1078 and Rv1079 are separated by 31 nucleotides Rv1077: Rv1077 - Probable cystathionine beta-synthase Cbs (serine sulfhydrase) (beta-thionase) (hemoprotein H-450), at 1,201,717 to 1,203,111 Rv1077 Rv1078: Rv1078 - Probable proline-rich antigen homolog Pra, at 1,203,313 to 1,204,035 Rv1078 Rv1079: Rv1079 - Cystathionine gamma-synthase MetB (CGS) (O-succinylhomoserine [thiol]-lyase), at 1,204,067 to 1,205,233 Rv1079 Position (kb) 1203 1204 1205Strain fitness (log2 ratio) -3 -2 -1 0 1 2 3at 1202.318 kb on + strand, within Rv1077at 1202.318 kb on + strand, within Rv1077at 1202.319 kb on - strand, within Rv1077at 1202.353 kb on + strand, within Rv1077at 1202.378 kb on - strand, within Rv1077at 1202.378 kb on - strand, within Rv1077at 1202.419 kb on + strand, within Rv1077at 1202.420 kb on - strand, within Rv1077at 1202.617 kb on + strand, within Rv1077at 1202.618 kb on - strand, within Rv1077at 1202.618 kb on - strand, within Rv1077at 1203.067 kb on + strandat 1203.255 kb on + strandat 1203.256 kb on - strandat 1204.175 kb on + strandat 1204.175 kb on + strandat 1204.176 kb on - strandat 1204.232 kb on + strand, within Rv1079at 1204.359 kb on + strand, within Rv1079at 1204.360 kb on - strand, within Rv1079at 1204.419 kb on + strand, within Rv1079at 1204.419 kb on + strand, within Rv1079at 1204.419 kb on + strand, within Rv1079at 1204.419 kb on + strand, within Rv1079at 1204.451 kb on + strand, within Rv1079at 1204.499 kb on - strand, within Rv1079at 1204.691 kb on + strand, within Rv1079at 1204.812 kb on - strand, within Rv1079

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Per-strain Table

Position Strand Gene LocusTag Fraction no stress control
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1,202,318 + Rv1077 0.43 -0.1
1,202,318 + Rv1077 0.43 -0.1
1,202,319 - Rv1077 0.43 -0.1
1,202,353 + Rv1077 0.46 -0.2
1,202,378 - Rv1077 0.47 -0.7
1,202,378 - Rv1077 0.47 -0.0
1,202,419 + Rv1077 0.50 +0.8
1,202,420 - Rv1077 0.50 -0.2
1,202,617 + Rv1077 0.65 +1.9
1,202,618 - Rv1077 0.65 +0.0
1,202,618 - Rv1077 0.65 -0.5
1,203,067 + -0.1
1,203,255 + -0.7
1,203,256 - -0.0
1,204,175 + +0.2
1,204,175 + +2.9
1,204,176 - +1.6
1,204,232 + Rv1079 0.14 -0.3
1,204,359 + Rv1079 0.25 -1.4
1,204,360 - Rv1079 0.25 -0.5
1,204,419 + Rv1079 0.30 -0.3
1,204,419 + Rv1079 0.30 -0.2
1,204,419 + Rv1079 0.30 -1.4
1,204,419 + Rv1079 0.30 -1.1
1,204,451 + Rv1079 0.33 -2.9
1,204,499 - Rv1079 0.37 -0.1
1,204,691 + Rv1079 0.53 -0.7
1,204,812 - Rv1079 0.64 -0.6

Or see this region's nucleotide sequence