Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0957

Experiment: no stress control

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv0955 and Rv0956 are separated by 115 nucleotidesRv0956 and Rv0957 overlap by 4 nucleotidesRv0957 and Rv0958 are separated by 106 nucleotides Rv0955: Rv0955 - Probable conserved integral membrane protein, at 1,066,078 to 1,067,445 Rv0955 Rv0956: Rv0956 - Probable 5'-phosphoribosylglycinamide formyltransferase PurN (GART) (gar transformylase) (5'-phosphoribosylglycinamide transformylase), at 1,067,561 to 1,068,208 Rv0956 Rv0957: Rv0957 - Probable bifunctional purine biosynthesis protein PurH: phosphoribosylaminoimidazolecarboxamide formyltransferase (AICAR transformylase) (5'-phosphoribosyl-5-aminoimidazole-4-carboxamide formyltransferase) + inosinemonophosphate cyclohydrolase (imp cyclohydrolase) (inosinicase) (imp synthetase) (ATIC), at 1,068,205 to 1,069,776 Rv0957 Rv0958: Rv0958 - Possible magnesium chelatase, at 1,069,883 to 1,071,262 Rv0958 Position (kb) 1068 1069 1070Strain fitness (log2 ratio) -1 0 1at 1067.288 kb on + strand, within Rv0955at 1067.388 kb on + strandat 1067.491 kb on + strandat 1067.549 kb on + strandat 1067.549 kb on + strandat 1068.201 kb on + strandat 1069.869 kb on - strandat 1069.894 kb on + strandat 1069.894 kb on + strandat 1070.192 kb on + strand, within Rv0958at 1070.193 kb on - strand, within Rv0958at 1070.248 kb on - strand, within Rv0958at 1070.248 kb on - strand, within Rv0958at 1070.279 kb on + strand, within Rv0958at 1070.570 kb on + strand, within Rv0958at 1070.570 kb on + strand, within Rv0958at 1070.708 kb on + strand, within Rv0958

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Per-strain Table

Position Strand Gene LocusTag Fraction no stress control
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1,067,288 + Rv0955 0.88 +0.1
1,067,388 + -0.1
1,067,491 + -0.3
1,067,549 + +0.5
1,067,549 + +0.5
1,068,201 + -0.4
1,069,869 - -0.2
1,069,894 + -1.2
1,069,894 + -0.0
1,070,192 + Rv0958 0.22 -0.1
1,070,193 - Rv0958 0.22 -0.2
1,070,248 - Rv0958 0.26 -0.2
1,070,248 - Rv0958 0.26 -0.0
1,070,279 + Rv0958 0.29 -0.3
1,070,570 + Rv0958 0.50 +0.1
1,070,570 + Rv0958 0.50 -0.3
1,070,708 + Rv0958 0.60 +0.5

Or see this region's nucleotide sequence