Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0553

Experiment: no stress control

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv0552 and Rv0553 overlap by 4 nucleotidesRv0553 and Rv0554 overlap by 4 nucleotidesRv0554 and Rv0555 are separated by 42 nucleotides Rv0552: Rv0552 - Conserved protein, at 642,889 to 644,493 Rv0552 Rv0553: Rv0553 - Probable muconate cycloisomerase MenC (cis,cis-muconate lactonizing enzyme) (MLE), at 644,490 to 645,470 Rv0553 Rv0554: Rv0554 - Possible peroxidase BpoC (non-haem peroxidase), at 645,467 to 646,255 Rv0554 Rv0555: Rv0555 - Probable bifunctional menaquinone biosynthesis protein MenD : 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase (SHCHC synthase) + 2-oxoglutarate decarboxylase (alpha-ketoglutarate decarboxylase) (KDC), at 646,298 to 647,962 Rv0555 Position (kb) 644 645 646Strain fitness (log2 ratio) -2 -1 0 1at 643.837 kb on + strand, within Rv0552at 643.945 kb on + strand, within Rv0552at 643.945 kb on + strand, within Rv0552at 644.083 kb on + strand, within Rv0552at 644.083 kb on + strand, within Rv0552at 644.175 kb on + strand, within Rv0552at 644.175 kb on + strand, within Rv0552at 644.389 kb on - strandat 645.694 kb on - strand, within Rv0554at 645.694 kb on - strand, within Rv0554at 645.857 kb on + strand, within Rv0554at 645.858 kb on - strand, within Rv0554at 645.887 kb on + strand, within Rv0554at 645.887 kb on + strand, within Rv0554at 645.887 kb on + strand, within Rv0554at 645.906 kb on + strand, within Rv0554at 645.907 kb on - strand, within Rv0554at 645.989 kb on - strand, within Rv0554at 645.989 kb on - strand, within Rv0554at 646.018 kb on - strand, within Rv0554at 646.116 kb on - strand, within Rv0554at 646.293 kb on + strand

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Per-strain Table

Position Strand Gene LocusTag Fraction no stress control
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643,837 + Rv0552 0.59 -2.0
643,945 + Rv0552 0.66 +0.0
643,945 + Rv0552 0.66 -0.3
644,083 + Rv0552 0.74 -0.6
644,083 + Rv0552 0.74 -0.8
644,175 + Rv0552 0.80 +0.1
644,175 + Rv0552 0.80 +0.4
644,389 - -0.7
645,694 - Rv0554 0.29 +0.7
645,694 - Rv0554 0.29 -0.1
645,857 + Rv0554 0.49 +0.5
645,858 - Rv0554 0.50 +0.1
645,887 + Rv0554 0.53 +0.5
645,887 + Rv0554 0.53 +0.7
645,887 + Rv0554 0.53 +0.2
645,906 + Rv0554 0.56 +0.5
645,907 - Rv0554 0.56 +0.4
645,989 - Rv0554 0.66 +0.5
645,989 - Rv0554 0.66 +0.2
646,018 - Rv0554 0.70 +0.3
646,116 - Rv0554 0.82 +0.2
646,293 + -2.1

Or see this region's nucleotide sequence