Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0524

Experiment: no stress control

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv0522 and Rv0523c overlap by 17 nucleotidesRv0523c and Rv0524 are separated by 113 nucleotidesRv0524 and Rv0525 overlap by 1 nucleotidesRv0525 and Rv0526 are separated by 14 nucleotides Rv0522: Rv0522 - Probable GABA permease GabP (4-amino butyrate transport carrier) (GAMA-aminobutyrate permease), at 613,038 to 614,342 Rv0522 Rv0523c: Rv0523c - Conserved protein, at 614,326 to 614,721 Rv0523c Rv0524: Rv0524 - Probable glutamate-1-semialdehyde 2,1-aminomutase HemL (GSA) (glutamate-1-semialdehyde aminotransferase) (GSA-at), at 614,835 to 616,223 Rv0524 Rv0525: Rv0525 - Conserved protein, at 616,223 to 616,831 Rv0525 Rv0526: Rv0526 - Possible thioredoxin protein (thiol-disulfide interchange protein), at 616,846 to 617,496 Rv0526 Position (kb) 614 615 616 617Strain fitness (log2 ratio) -1 0 1 2at 613.884 kb on + strand, within Rv0522at 613.884 kb on + strand, within Rv0522at 613.884 kb on + strand, within Rv0522at 613.884 kb on + strand, within Rv0522at 613.885 kb on - strand, within Rv0522at 613.885 kb on - strand, within Rv0522at 613.885 kb on - strand, within Rv0522at 613.885 kb on - strand, within Rv0522at 613.885 kb on - strand, within Rv0522at 614.156 kb on - strand, within Rv0522at 614.295 kb on + strandat 614.296 kb on - strandat 614.296 kb on - strandat 614.348 kb on - strandat 614.402 kb on + strand, within Rv0523cat 614.403 kb on - strand, within Rv0523cat 614.684 kb on + strandat 614.685 kb on - strandat 614.685 kb on - strandat 614.713 kb on + strandat 614.827 kb on + strand

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Per-strain Table

Position Strand Gene LocusTag Fraction no stress control
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613,884 + Rv0522 0.65 -1.3
613,884 + Rv0522 0.65 -0.2
613,884 + Rv0522 0.65 +0.4
613,884 + Rv0522 0.65 +0.2
613,885 - Rv0522 0.65 -0.2
613,885 - Rv0522 0.65 -0.1
613,885 - Rv0522 0.65 -0.2
613,885 - Rv0522 0.65 +0.5
613,885 - Rv0522 0.65 -0.3
614,156 - Rv0522 0.86 +0.0
614,295 + -0.9
614,296 - -0.1
614,296 - +1.5
614,348 - +0.2
614,402 + Rv0523c 0.19 +1.8
614,403 - Rv0523c 0.19 -0.5
614,684 + -0.2
614,685 - +0.8
614,685 - +1.8
614,713 + +1.1
614,827 + -0.4

Or see this region's nucleotide sequence