Experiment: no stress control
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv0511 and Rv0512 are separated by 85 nucleotides Rv0512 and Rv0513 are separated by 12 nucleotides Rv0513 and Rv0514 overlap by 4 nucleotides Rv0514 and Rv0515 are separated by 102 nucleotides
Rv0511: Rv0511 - Probable uroporphyrin-III C-methyltransferase HemD (uroporphyrinogen III methylase) (urogen III methylase) (SUMT) (urogen III methylase) (UROM), at 602,819 to 604,516
Rv0511
Rv0512: Rv0512 - Probable delta-aminolevulinic acid dehydratase HemB (porphobilinogen synthase) (ALAD) (ALADH), at 604,602 to 605,591
Rv0512
Rv0513: Rv0513 - Possible conserved transmembrane protein, at 605,604 to 606,152
Rv0513
Rv0514: Rv0514 - Possible transmembrane protein, at 606,149 to 606,448
Rv0514
Rv0515: Rv0515 - Conserved 13E12 repeat family protein, at 606,551 to 608,062
Rv0515
Position (kb) 604
605
606 Strain fitness (log2 ratio) -2
-1
0
1
2 at 604.514 kb on + strand at 605.585 kb on + strand at 605.585 kb on + strand at 605.586 kb on - strand at 605.586 kb on - strand at 605.643 kb on + strand at 605.643 kb on + strand at 605.644 kb on - strand at 605.644 kb on - strand at 605.889 kb on + strand, within Rv0513 at 606.293 kb on + strand, within Rv0514 at 606.293 kb on + strand, within Rv0514 at 606.293 kb on + strand, within Rv0514 at 606.293 kb on + strand, within Rv0514 at 606.294 kb on - strand, within Rv0514 at 606.294 kb on - strand, within Rv0514
Per-strain Table
Position Strand Gene LocusTag Fraction no stress control remove 604,514 + -1.1 605,585 + -1.2 605,585 + +2.1 605,586 - -1.0 605,586 - -1.0 605,643 + -1.4 605,643 + +1.8 605,644 - -1.0 605,644 - +0.0 605,889 + Rv0513 0.52 -1.1 606,293 + Rv0514 0.48 -1.8 606,293 + Rv0514 0.48 -0.7 606,293 + Rv0514 0.48 -0.1 606,293 + Rv0514 0.48 -0.1 606,294 - Rv0514 0.48 -0.4 606,294 - Rv0514 0.48 -0.8
Or see this region's nucleotide sequence