Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0379

Experiment: no stress control

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv0377 and Rv0378 are separated by 250 nucleotidesRv0378 and Rv0379 are separated by 118 nucleotidesRv0379 and Rv0380c are separated by 75 nucleotidesRv0380c and Rv0381c are separated by 95 nucleotides Rv0377: Rv0377 - Probable transcriptional regulatory protein (probably LysR-family), at 454,421 to 455,386 Rv0377 Rv0378: Rv0378 - Conserved hypothetical glycine rich protein, at 455,637 to 455,858 Rv0378 Rv0379: Rv0379 - Possible protein transport protein SecE2, at 455,977 to 456,192 Rv0379 Rv0380c: Rv0380c - Possible RNA methyltransferase (RNA methylase), at 456,268 to 456,819 Rv0380c Rv0381c: Rv0381c - Hypothetical protein, at 456,915 to 457,823 Rv0381c Position (kb) 455 456 457Strain fitness (log2 ratio) -1 0 1at 455.025 kb on + strand, within Rv0377at 455.026 kb on - strand, within Rv0377at 455.308 kb on + strandat 455.308 kb on + strandat 455.786 kb on - strand, within Rv0378at 455.961 kb on + strandat 455.961 kb on + strandat 455.963 kb on + strandat 455.963 kb on + strandat 455.970 kb on + strandat 455.986 kb on + strandat 455.987 kb on - strandat 455.987 kb on - strandat 455.987 kb on - strandat 456.139 kb on + strand, within Rv0379at 456.139 kb on + strand, within Rv0379at 456.190 kb on + strandat 456.269 kb on + strandat 456.270 kb on - strandat 456.412 kb on - strand, within Rv0380cat 456.827 kb on + strandat 456.895 kb on - strandat 456.968 kb on - strandat 456.999 kb on - strandat 456.999 kb on - strandat 457.013 kb on + strand, within Rv0381cat 457.066 kb on + strand, within Rv0381cat 457.066 kb on + strand, within Rv0381cat 457.066 kb on + strand, within Rv0381cat 457.067 kb on - strand, within Rv0381c

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Per-strain Table

Position Strand Gene LocusTag Fraction no stress control
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455,025 + Rv0377 0.63 -0.4
455,026 - Rv0377 0.63 -0.9
455,308 + -0.0
455,308 + +0.6
455,786 - Rv0378 0.67 +0.3
455,961 + -0.8
455,961 + -1.2
455,963 + -1.6
455,963 + +0.1
455,970 + -0.2
455,986 + -0.6
455,987 - +0.0
455,987 - +0.2
455,987 - -0.3
456,139 + Rv0379 0.75 -0.2
456,139 + Rv0379 0.75 +0.3
456,190 + -0.1
456,269 + -0.6
456,270 - -0.1
456,412 - Rv0380c 0.26 +0.6
456,827 + -0.1
456,895 - -1.7
456,968 - +0.1
456,999 - -0.1
456,999 - -0.8
457,013 + Rv0381c 0.11 -0.3
457,066 + Rv0381c 0.17 -1.4
457,066 + Rv0381c 0.17 -0.9
457,066 + Rv0381c 0.17 -0.7
457,067 - Rv0381c 0.17 -0.1

Or see this region's nucleotide sequence