Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0352

Experiment: no stress control

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv0350 and Rv0351 overlap by 4 nucleotidesRv0351 and Rv0352 are separated by 35 nucleotidesRv0352 and Rv0353 overlap by 1 nucleotidesRv0353 and Rv0354c are separated by 249 nucleotides Rv0350: Rv0350 - Probable chaperone protein DnaK (heat shock protein 70) (heat shock 70 kDa protein) (HSP70), at 419,835 to 421,712 Rv0350 Rv0351: Rv0351 - Probable GrpE protein (HSP-70 cofactor), at 421,709 to 422,416 Rv0351 Rv0352: Rv0352 - Probable chaperone protein DnaJ1, at 422,452 to 423,639 Rv0352 Rv0353: Rv0353 - Probable heat shock protein transcriptional repressor HspR (MerR family), at 423,639 to 424,019 Rv0353 Rv0354c: Rv0354c - PPE family protein PPE7, at 424,269 to 424,694 Rv0354c Position (kb) 422 423 424Strain fitness (log2 ratio) -2 -1 0 1 2at 422.414 kb on + strandat 423.631 kb on - strandat 423.728 kb on + strand, within Rv0353at 423.728 kb on + strand, within Rv0353at 423.728 kb on + strand, within Rv0353at 423.732 kb on + strand, within Rv0353at 423.732 kb on + strand, within Rv0353at 423.733 kb on - strand, within Rv0353at 423.733 kb on - strand, within Rv0353at 424.031 kb on + strandat 424.263 kb on + strandat 424.263 kb on + strandat 424.264 kb on - strandat 424.264 kb on - strandat 424.270 kb on + strandat 424.271 kb on - strandat 424.604 kb on - strand, within Rv0354cat 424.632 kb on + strand, within Rv0354cat 424.632 kb on + strand, within Rv0354cat 424.632 kb on + strand, within Rv0354c

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Per-strain Table

Position Strand Gene LocusTag Fraction no stress control
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422,414 + -0.2
423,631 - -0.3
423,728 + Rv0353 0.23 -1.1
423,728 + Rv0353 0.23 -1.5
423,728 + Rv0353 0.23 -0.6
423,732 + Rv0353 0.24 -0.7
423,732 + Rv0353 0.24 -2.6
423,733 - Rv0353 0.25 -1.0
423,733 - Rv0353 0.25 -0.3
424,031 + +0.1
424,263 + -0.3
424,263 + -0.3
424,264 - -0.2
424,264 - -0.2
424,270 + +1.8
424,271 - +0.8
424,604 - Rv0354c 0.79 -0.6
424,632 + Rv0354c 0.85 +0.1
424,632 + Rv0354c 0.85 -0.7
424,632 + Rv0354c 0.85 -0.5

Or see this region's nucleotide sequence