Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0011c

Experiment: no stress control

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv0009 and Rv0010c are separated by 116 nucleotidesRv0010c and Rv0011c are separated by 155 nucleotidesRv0011c and Rv0012 are separated by 93 nucleotidesRv0012 and Rv0013 are separated by 36 nucleotides Rv0009: Rv0009 - Probable iron-regulated peptidyl-prolyl cis-trans isomerase A PpiA (PPIase A) (rotamase A), at 12,468 to 13,016 Rv0009 Rv0010c: Rv0010c - Probable conserved membrane protein, at 13,133 to 13,558 Rv0010c Rv0011c: Rv0011c - Probable conserved transmembrane protein, at 13,714 to 13,995 Rv0011c Rv0012: Rv0012 - Probable conserved membrane protein, at 14,089 to 14,877 Rv0012 Rv0013: Rv0013 - Possible anthranilate synthase component II TrpG (glutamine amidotransferase), at 14,914 to 15,612 Rv0013 Position (kb) 13 14Strain fitness (log2 ratio) -2 -1 0 1 2at 13.025 kb on + strandat 13.025 kb on + strandat 13.156 kb on - strandat 13.309 kb on + strand, within Rv0010cat 13.309 kb on + strand, within Rv0010cat 13.323 kb on - strand, within Rv0010cat 13.323 kb on - strand, within Rv0010cat 13.325 kb on + strand, within Rv0010cat 13.326 kb on - strand, within Rv0010cat 13.326 kb on - strand, within Rv0010cat 13.369 kb on + strand, within Rv0010cat 13.568 kb on - strandat 14.059 kb on + strandat 14.059 kb on + strandat 14.089 kb on - strandat 14.097 kb on - strandat 14.097 kb on - strandat 14.622 kb on - strand, within Rv0012at 14.661 kb on + strand, within Rv0012at 14.662 kb on - strand, within Rv0012at 14.662 kb on - strand, within Rv0012at 14.665 kb on + strand, within Rv0012at 14.666 kb on - strand, within Rv0012at 14.666 kb on - strand, within Rv0012at 14.666 kb on - strand, within Rv0012at 14.750 kb on - strand, within Rv0012at 14.750 kb on - strand, within Rv0012at 14.758 kb on + strand, within Rv0012at 14.758 kb on + strand, within Rv0012at 14.813 kb on + strand

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Per-strain Table

Position Strand Gene LocusTag Fraction no stress control
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13,025 + +1.9
13,025 + -0.0
13,156 - -0.2
13,309 + Rv0010c 0.41 -0.1
13,309 + Rv0010c 0.41 -2.3
13,323 - Rv0010c 0.45 -0.2
13,323 - Rv0010c 0.45 -0.6
13,325 + Rv0010c 0.45 +0.3
13,326 - Rv0010c 0.45 +0.5
13,326 - Rv0010c 0.45 +0.3
13,369 + Rv0010c 0.55 +0.3
13,568 - +0.6
14,059 + +0.7
14,059 + -1.8
14,089 - -0.7
14,097 - -1.1
14,097 - -0.0
14,622 - Rv0012 0.68 +0.0
14,661 + Rv0012 0.72 -0.3
14,662 - Rv0012 0.73 +0.3
14,662 - Rv0012 0.73 +0.4
14,665 + Rv0012 0.73 -0.9
14,666 - Rv0012 0.73 +0.5
14,666 - Rv0012 0.73 +0.5
14,666 - Rv0012 0.73 -0.5
14,750 - Rv0012 0.84 -0.8
14,750 - Rv0012 0.84 +0.4
14,758 + Rv0012 0.85 +0.4
14,758 + Rv0012 0.85 +0.6
14,813 + -0.8

Or see this region's nucleotide sequence