Experiment: Cisplatin 0.008 mg/ml
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Pf6N2E2_2682 and Pf6N2E2_2683 are separated by 14 nucleotides Pf6N2E2_2683 and Pf6N2E2_2684 are separated by 4 nucleotides Pf6N2E2_2684 and Pf6N2E2_2685 are separated by 84 nucleotides
Pf6N2E2_2682 - Transcriptional regulator, LysR family, at 3,170,621 to 3,171,544
_2682
Pf6N2E2_2683 - Beta-ketoadipate enol-lactone hydrolase (EC 3.1.1.24), at 3,171,559 to 3,172,362
_2683
Pf6N2E2_2684 - Peptidyl-prolyl cis-trans isomerase PpiA precursor (EC 5.2.1.8), at 3,172,367 to 3,172,930
_2684
Pf6N2E2_2685 - Lipid A export ATP-binding/permease protein MsbA, at 3,173,015 to 3,174,847
_2685
Position (kb)
3172
3173 Strain fitness (log2 ratio)
-3
-2
-1
0
1
2 at 3171.565 kb on + strand at 3171.566 kb on - strand at 3171.595 kb on + strand at 3171.596 kb on - strand at 3171.596 kb on - strand at 3172.025 kb on + strand, within Pf6N2E2_2683 at 3172.025 kb on + strand, within Pf6N2E2_2683 at 3172.026 kb on - strand, within Pf6N2E2_2683 at 3172.052 kb on + strand, within Pf6N2E2_2683 at 3172.099 kb on + strand, within Pf6N2E2_2683 at 3172.099 kb on + strand, within Pf6N2E2_2683 at 3172.099 kb on + strand, within Pf6N2E2_2683 at 3172.100 kb on - strand, within Pf6N2E2_2683 at 3172.100 kb on - strand, within Pf6N2E2_2683 at 3172.100 kb on - strand, within Pf6N2E2_2683 at 3172.100 kb on - strand, within Pf6N2E2_2683 at 3172.100 kb on - strand, within Pf6N2E2_2683 at 3172.195 kb on + strand, within Pf6N2E2_2683 at 3172.195 kb on + strand, within Pf6N2E2_2683 at 3172.195 kb on + strand, within Pf6N2E2_2683 at 3172.195 kb on + strand, within Pf6N2E2_2683 at 3172.196 kb on - strand, within Pf6N2E2_2683 at 3172.196 kb on - strand, within Pf6N2E2_2683 at 3172.196 kb on - strand, within Pf6N2E2_2683 at 3172.196 kb on - strand, within Pf6N2E2_2683 at 3172.196 kb on - strand, within Pf6N2E2_2683 at 3172.222 kb on + strand, within Pf6N2E2_2683 at 3172.222 kb on + strand, within Pf6N2E2_2683 at 3172.222 kb on + strand, within Pf6N2E2_2683 at 3172.222 kb on + strand, within Pf6N2E2_2683 at 3172.222 kb on + strand, within Pf6N2E2_2683 at 3172.223 kb on - strand, within Pf6N2E2_2683 at 3172.223 kb on - strand, within Pf6N2E2_2683 at 3172.223 kb on - strand, within Pf6N2E2_2683 at 3172.233 kb on - strand, within Pf6N2E2_2683 at 3172.401 kb on + strand at 3172.401 kb on + strand at 3172.402 kb on - strand at 3172.402 kb on - strand at 3172.452 kb on + strand, within Pf6N2E2_2684 at 3172.452 kb on + strand, within Pf6N2E2_2684 at 3172.452 kb on + strand, within Pf6N2E2_2684 at 3172.452 kb on + strand, within Pf6N2E2_2684 at 3172.452 kb on + strand, within Pf6N2E2_2684 at 3172.452 kb on + strand, within Pf6N2E2_2684 at 3172.452 kb on + strand, within Pf6N2E2_2684 at 3172.452 kb on + strand, within Pf6N2E2_2684 at 3172.452 kb on + strand, within Pf6N2E2_2684 at 3172.452 kb on + strand, within Pf6N2E2_2684 at 3172.452 kb on + strand, within Pf6N2E2_2684 at 3172.452 kb on + strand, within Pf6N2E2_2684 at 3172.452 kb on + strand, within Pf6N2E2_2684 at 3172.453 kb on - strand, within Pf6N2E2_2684 at 3172.453 kb on - strand, within Pf6N2E2_2684 at 3172.453 kb on - strand, within Pf6N2E2_2684 at 3172.453 kb on - strand, within Pf6N2E2_2684 at 3172.453 kb on - strand, within Pf6N2E2_2684 at 3172.453 kb on - strand, within Pf6N2E2_2684 at 3172.453 kb on - strand, within Pf6N2E2_2684 at 3172.453 kb on - strand, within Pf6N2E2_2684 at 3172.453 kb on - strand, within Pf6N2E2_2684 at 3172.453 kb on - strand, within Pf6N2E2_2684 at 3172.453 kb on - strand, within Pf6N2E2_2684 at 3172.453 kb on - strand, within Pf6N2E2_2684 at 3172.453 kb on - strand, within Pf6N2E2_2684 at 3172.453 kb on - strand, within Pf6N2E2_2684 at 3172.453 kb on - strand, within Pf6N2E2_2684 at 3172.453 kb on - strand, within Pf6N2E2_2684 at 3172.517 kb on - strand, within Pf6N2E2_2684 at 3172.517 kb on - strand, within Pf6N2E2_2684 at 3172.517 kb on - strand, within Pf6N2E2_2684 at 3172.535 kb on + strand, within Pf6N2E2_2684 at 3172.535 kb on + strand, within Pf6N2E2_2684 at 3172.536 kb on - strand, within Pf6N2E2_2684 at 3172.536 kb on - strand, within Pf6N2E2_2684 at 3172.536 kb on - strand, within Pf6N2E2_2684 at 3172.536 kb on - strand, within Pf6N2E2_2684 at 3172.553 kb on + strand, within Pf6N2E2_2684 at 3172.553 kb on + strand, within Pf6N2E2_2684 at 3172.980 kb on - strand at 3173.011 kb on - strand at 3173.011 kb on - strand at 3173.011 kb on - strand at 3173.011 kb on - strand at 3173.048 kb on - strand at 3173.099 kb on + strand at 3173.099 kb on + strand at 3173.099 kb on + strand at 3173.099 kb on + strand at 3173.099 kb on + strand at 3173.100 kb on - strand at 3173.100 kb on - strand at 3173.100 kb on - strand at 3173.100 kb on - strand at 3173.100 kb on - strand at 3173.100 kb on - strand at 3173.105 kb on + strand at 3173.105 kb on + strand at 3173.105 kb on + strand at 3173.105 kb on + strand at 3173.106 kb on - strand at 3173.106 kb on - strand at 3173.106 kb on - strand at 3173.106 kb on - strand at 3173.106 kb on - strand at 3173.106 kb on - strand at 3173.106 kb on - strand at 3173.106 kb on - strand at 3173.108 kb on + strand at 3173.109 kb on - strand at 3173.193 kb on - strand at 3173.387 kb on + strand, within Pf6N2E2_2685 at 3173.387 kb on + strand, within Pf6N2E2_2685 at 3173.387 kb on + strand, within Pf6N2E2_2685 at 3173.388 kb on - strand, within Pf6N2E2_2685 at 3173.388 kb on - strand, within Pf6N2E2_2685 at 3173.388 kb on - strand, within Pf6N2E2_2685 at 3173.388 kb on - strand, within Pf6N2E2_2685 at 3173.388 kb on - strand, within Pf6N2E2_2685 at 3173.388 kb on - strand, within Pf6N2E2_2685 at 3173.388 kb on - strand, within Pf6N2E2_2685 at 3173.388 kb on - strand, within Pf6N2E2_2685 at 3173.388 kb on - strand, within Pf6N2E2_2685 at 3173.522 kb on + strand, within Pf6N2E2_2685 at 3173.522 kb on + strand, within Pf6N2E2_2685 at 3173.522 kb on + strand, within Pf6N2E2_2685 at 3173.522 kb on + strand, within Pf6N2E2_2685 at 3173.522 kb on + strand, within Pf6N2E2_2685 at 3173.523 kb on - strand, within Pf6N2E2_2685 at 3173.523 kb on - strand, within Pf6N2E2_2685 at 3173.523 kb on - strand, within Pf6N2E2_2685 at 3173.523 kb on - strand, within Pf6N2E2_2685 at 3173.600 kb on + strand, within Pf6N2E2_2685 at 3173.600 kb on + strand, within Pf6N2E2_2685 at 3173.601 kb on - strand, within Pf6N2E2_2685 at 3173.618 kb on + strand, within Pf6N2E2_2685 at 3173.618 kb on + strand, within Pf6N2E2_2685 at 3173.618 kb on + strand, within Pf6N2E2_2685 at 3173.619 kb on - strand, within Pf6N2E2_2685 at 3173.753 kb on + strand, within Pf6N2E2_2685 at 3173.754 kb on - strand, within Pf6N2E2_2685
Per-strain Table
Position Strand Gene LocusTag Fraction Cisplatin 0.008 mg/ml remove 3,171,565 + +1.4 3,171,566 - +0.3 3,171,595 + -0.5 3,171,596 - -2.9 3,171,596 - -0.6 3,172,025 + Pf6N2E2_2683 0.58 -0.1 3,172,025 + Pf6N2E2_2683 0.58 +0.0 3,172,026 - Pf6N2E2_2683 0.58 +1.3 3,172,052 + Pf6N2E2_2683 0.61 +1.3 3,172,099 + Pf6N2E2_2683 0.67 -0.5 3,172,099 + Pf6N2E2_2683 0.67 -0.5 3,172,099 + Pf6N2E2_2683 0.67 +0.5 3,172,100 - Pf6N2E2_2683 0.67 +0.0 3,172,100 - Pf6N2E2_2683 0.67 -0.3 3,172,100 - Pf6N2E2_2683 0.67 -1.5 3,172,100 - Pf6N2E2_2683 0.67 -0.7 3,172,100 - Pf6N2E2_2683 0.67 +0.4 3,172,195 + Pf6N2E2_2683 0.79 +0.5 3,172,195 + Pf6N2E2_2683 0.79 -0.1 3,172,195 + Pf6N2E2_2683 0.79 +0.2 3,172,195 + Pf6N2E2_2683 0.79 -1.6 3,172,196 - Pf6N2E2_2683 0.79 -0.2 3,172,196 - Pf6N2E2_2683 0.79 +2.0 3,172,196 - Pf6N2E2_2683 0.79 -0.2 3,172,196 - Pf6N2E2_2683 0.79 -0.9 3,172,196 - Pf6N2E2_2683 0.79 +0.2 3,172,222 + Pf6N2E2_2683 0.82 -0.9 3,172,222 + Pf6N2E2_2683 0.82 +0.5 3,172,222 + Pf6N2E2_2683 0.82 +0.4 3,172,222 + Pf6N2E2_2683 0.82 +0.5 3,172,222 + Pf6N2E2_2683 0.82 +0.2 3,172,223 - Pf6N2E2_2683 0.83 -0.2 3,172,223 - Pf6N2E2_2683 0.83 -0.0 3,172,223 - Pf6N2E2_2683 0.83 -0.7 3,172,233 - Pf6N2E2_2683 0.84 +0.0 3,172,401 + -0.9 3,172,401 + -1.0 3,172,402 - -0.6 3,172,402 - +1.1 3,172,452 + Pf6N2E2_2684 0.15 +0.5 3,172,452 + Pf6N2E2_2684 0.15 -0.6 3,172,452 + Pf6N2E2_2684 0.15 -1.3 3,172,452 + Pf6N2E2_2684 0.15 +0.9 3,172,452 + Pf6N2E2_2684 0.15 -1.3 3,172,452 + Pf6N2E2_2684 0.15 +1.1 3,172,452 + Pf6N2E2_2684 0.15 -0.5 3,172,452 + Pf6N2E2_2684 0.15 -0.2 3,172,452 + Pf6N2E2_2684 0.15 -0.9 3,172,452 + Pf6N2E2_2684 0.15 +1.2 3,172,452 + Pf6N2E2_2684 0.15 +0.6 3,172,452 + Pf6N2E2_2684 0.15 -0.8 3,172,452 + Pf6N2E2_2684 0.15 -0.1 3,172,453 - Pf6N2E2_2684 0.15 -0.3 3,172,453 - Pf6N2E2_2684 0.15 -0.5 3,172,453 - Pf6N2E2_2684 0.15 -1.4 3,172,453 - Pf6N2E2_2684 0.15 -1.1 3,172,453 - Pf6N2E2_2684 0.15 +0.5 3,172,453 - Pf6N2E2_2684 0.15 -0.2 3,172,453 - Pf6N2E2_2684 0.15 +0.2 3,172,453 - Pf6N2E2_2684 0.15 -0.4 3,172,453 - Pf6N2E2_2684 0.15 -0.9 3,172,453 - Pf6N2E2_2684 0.15 -0.8 3,172,453 - Pf6N2E2_2684 0.15 -0.0 3,172,453 - Pf6N2E2_2684 0.15 +1.4 3,172,453 - Pf6N2E2_2684 0.15 +0.8 3,172,453 - Pf6N2E2_2684 0.15 +1.4 3,172,453 - Pf6N2E2_2684 0.15 +1.1 3,172,453 - Pf6N2E2_2684 0.15 -0.5 3,172,517 - Pf6N2E2_2684 0.27 -0.6 3,172,517 - Pf6N2E2_2684 0.27 -0.1 3,172,517 - Pf6N2E2_2684 0.27 +0.7 3,172,535 + Pf6N2E2_2684 0.30 +0.6 3,172,535 + Pf6N2E2_2684 0.30 +0.5 3,172,536 - Pf6N2E2_2684 0.30 +0.9 3,172,536 - Pf6N2E2_2684 0.30 -2.0 3,172,536 - Pf6N2E2_2684 0.30 +0.8 3,172,536 - Pf6N2E2_2684 0.30 +0.9 3,172,553 + Pf6N2E2_2684 0.33 -0.1 3,172,553 + Pf6N2E2_2684 0.33 +0.5 3,172,980 - -0.1 3,173,011 - -0.6 3,173,011 - -0.6 3,173,011 - -0.1 3,173,011 - +1.1 3,173,048 - +1.2 3,173,099 + +0.1 3,173,099 + +0.0 3,173,099 + -0.0 3,173,099 + +0.1 3,173,099 + -1.1 3,173,100 - +0.8 3,173,100 - +0.7 3,173,100 - -1.1 3,173,100 - +1.3 3,173,100 - +0.4 3,173,100 - -1.4 3,173,105 + +0.7 3,173,105 + +1.0 3,173,105 + +0.1 3,173,105 + -0.9 3,173,106 - -0.1 3,173,106 - +0.4 3,173,106 - +0.4 3,173,106 - +1.2 3,173,106 - +0.2 3,173,106 - +1.3 3,173,106 - +0.5 3,173,106 - -1.2 3,173,108 + -0.7 3,173,109 - +1.5 3,173,193 - -1.1 3,173,387 + Pf6N2E2_2685 0.20 +0.4 3,173,387 + Pf6N2E2_2685 0.20 -0.8 3,173,387 + Pf6N2E2_2685 0.20 -0.9 3,173,388 - Pf6N2E2_2685 0.20 +0.0 3,173,388 - Pf6N2E2_2685 0.20 -2.0 3,173,388 - Pf6N2E2_2685 0.20 +0.1 3,173,388 - Pf6N2E2_2685 0.20 -1.4 3,173,388 - Pf6N2E2_2685 0.20 +1.0 3,173,388 - Pf6N2E2_2685 0.20 +0.2 3,173,388 - Pf6N2E2_2685 0.20 +0.7 3,173,388 - Pf6N2E2_2685 0.20 -0.8 3,173,388 - Pf6N2E2_2685 0.20 +0.3 3,173,522 + Pf6N2E2_2685 0.28 -0.5 3,173,522 + Pf6N2E2_2685 0.28 -0.7 3,173,522 + Pf6N2E2_2685 0.28 -1.4 3,173,522 + Pf6N2E2_2685 0.28 +0.2 3,173,522 + Pf6N2E2_2685 0.28 -0.3 3,173,523 - Pf6N2E2_2685 0.28 +0.8 3,173,523 - Pf6N2E2_2685 0.28 +0.2 3,173,523 - Pf6N2E2_2685 0.28 -0.3 3,173,523 - Pf6N2E2_2685 0.28 +0.1 3,173,600 + Pf6N2E2_2685 0.32 +0.4 3,173,600 + Pf6N2E2_2685 0.32 +0.6 3,173,601 - Pf6N2E2_2685 0.32 -0.8 3,173,618 + Pf6N2E2_2685 0.33 +0.1 3,173,618 + Pf6N2E2_2685 0.33 -0.0 3,173,618 + Pf6N2E2_2685 0.33 +0.1 3,173,619 - Pf6N2E2_2685 0.33 -0.1 3,173,753 + Pf6N2E2_2685 0.40 -1.8 3,173,754 - Pf6N2E2_2685 0.40 +0.0
Or see this region's nucleotide sequence