Experiment: R2A with Vancomycin 0.5 mg/ml
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt RR42_RS11180 and RR42_RS11185 are separated by 62 nucleotides RR42_RS11185 and RR42_RS11190 are separated by 144 nucleotides RR42_RS11190 and RR42_RS11195 are separated by 33 nucleotides
RR42_RS11180: RR42_RS11180 - peptidylprolyl isomerase, at 2,387,795 to 2,388,589
_RS11180
RR42_RS11185: RR42_RS11185 - TetR family transcriptional regulator, at 2,388,652 to 2,389,299
_RS11185
RR42_RS11190: RR42_RS11190 - acyl-CoA dehydrogenase, at 2,389,444 to 2,391,066
_RS11190
RR42_RS11195: RR42_RS11195 - phosphohydrolase, at 2,391,100 to 2,392,311
_RS11195
Position (kb)
2389
2390
2391
2392 Strain fitness (log2 ratio)
-3
-2
-1
0
1
2 at 2388.587 kb on + strand at 2388.587 kb on + strand at 2388.588 kb on - strand at 2388.588 kb on - strand at 2388.689 kb on + strand at 2388.847 kb on + strand, within RR42_RS11185 at 2388.884 kb on + strand, within RR42_RS11185 at 2388.885 kb on - strand, within RR42_RS11185 at 2388.885 kb on - strand, within RR42_RS11185 at 2388.914 kb on + strand, within RR42_RS11185 at 2388.915 kb on - strand, within RR42_RS11185 at 2388.915 kb on - strand, within RR42_RS11185 at 2388.933 kb on - strand, within RR42_RS11185 at 2388.973 kb on + strand, within RR42_RS11185 at 2388.973 kb on + strand, within RR42_RS11185 at 2388.974 kb on - strand, within RR42_RS11185 at 2389.084 kb on + strand, within RR42_RS11185 at 2389.115 kb on + strand, within RR42_RS11185 at 2389.115 kb on + strand, within RR42_RS11185 at 2389.116 kb on - strand, within RR42_RS11185 at 2389.121 kb on + strand, within RR42_RS11185 at 2389.122 kb on - strand, within RR42_RS11185 at 2389.122 kb on - strand, within RR42_RS11185 at 2389.182 kb on - strand, within RR42_RS11185 at 2389.336 kb on + strand at 2389.337 kb on - strand at 2389.474 kb on + strand at 2389.474 kb on + strand at 2389.475 kb on - strand at 2389.475 kb on - strand at 2389.475 kb on - strand at 2389.483 kb on + strand at 2389.483 kb on + strand at 2389.484 kb on - strand at 2389.769 kb on - strand, within RR42_RS11190 at 2389.783 kb on + strand, within RR42_RS11190 at 2389.783 kb on + strand, within RR42_RS11190 at 2389.784 kb on - strand, within RR42_RS11190 at 2389.784 kb on - strand, within RR42_RS11190 at 2389.784 kb on - strand, within RR42_RS11190 at 2389.784 kb on - strand, within RR42_RS11190 at 2389.785 kb on + strand, within RR42_RS11190 at 2389.785 kb on + strand, within RR42_RS11190 at 2389.785 kb on + strand, within RR42_RS11190 at 2389.785 kb on + strand, within RR42_RS11190 at 2389.785 kb on + strand, within RR42_RS11190 at 2389.785 kb on + strand, within RR42_RS11190 at 2389.785 kb on + strand, within RR42_RS11190 at 2389.786 kb on - strand, within RR42_RS11190 at 2389.786 kb on - strand, within RR42_RS11190 at 2389.786 kb on - strand, within RR42_RS11190 at 2389.827 kb on + strand, within RR42_RS11190 at 2389.828 kb on - strand, within RR42_RS11190 at 2389.828 kb on - strand, within RR42_RS11190 at 2389.909 kb on + strand, within RR42_RS11190 at 2389.910 kb on - strand, within RR42_RS11190 at 2390.051 kb on - strand, within RR42_RS11190 at 2390.210 kb on + strand, within RR42_RS11190 at 2390.211 kb on - strand, within RR42_RS11190 at 2390.211 kb on - strand, within RR42_RS11190 at 2390.317 kb on + strand, within RR42_RS11190 at 2390.317 kb on + strand, within RR42_RS11190 at 2390.318 kb on - strand, within RR42_RS11190 at 2390.318 kb on - strand, within RR42_RS11190 at 2390.318 kb on - strand, within RR42_RS11190 at 2390.318 kb on - strand, within RR42_RS11190 at 2390.318 kb on - strand, within RR42_RS11190 at 2390.318 kb on - strand, within RR42_RS11190 at 2390.318 kb on - strand, within RR42_RS11190 at 2390.318 kb on - strand, within RR42_RS11190 at 2390.318 kb on - strand, within RR42_RS11190 at 2390.320 kb on - strand, within RR42_RS11190 at 2390.329 kb on - strand, within RR42_RS11190 at 2390.386 kb on + strand, within RR42_RS11190 at 2390.641 kb on + strand, within RR42_RS11190 at 2391.009 kb on + strand at 2391.236 kb on + strand, within RR42_RS11195 at 2391.237 kb on - strand, within RR42_RS11195 at 2391.336 kb on - strand, within RR42_RS11195 at 2391.372 kb on + strand, within RR42_RS11195 at 2391.372 kb on + strand, within RR42_RS11195 at 2391.387 kb on + strand, within RR42_RS11195 at 2391.387 kb on + strand, within RR42_RS11195 at 2391.387 kb on + strand, within RR42_RS11195 at 2391.387 kb on + strand, within RR42_RS11195 at 2391.387 kb on + strand, within RR42_RS11195 at 2391.388 kb on - strand, within RR42_RS11195 at 2391.405 kb on + strand, within RR42_RS11195 at 2391.405 kb on + strand, within RR42_RS11195 at 2391.406 kb on - strand, within RR42_RS11195 at 2391.407 kb on + strand, within RR42_RS11195 at 2391.470 kb on + strand, within RR42_RS11195 at 2391.470 kb on + strand, within RR42_RS11195 at 2391.471 kb on - strand, within RR42_RS11195 at 2391.588 kb on + strand, within RR42_RS11195 at 2391.589 kb on - strand, within RR42_RS11195 at 2391.827 kb on + strand, within RR42_RS11195 at 2391.827 kb on + strand, within RR42_RS11195 at 2391.827 kb on + strand, within RR42_RS11195 at 2391.827 kb on + strand, within RR42_RS11195 at 2391.828 kb on - strand, within RR42_RS11195 at 2391.828 kb on - strand, within RR42_RS11195 at 2391.833 kb on + strand, within RR42_RS11195 at 2391.833 kb on + strand, within RR42_RS11195 at 2391.833 kb on + strand, within RR42_RS11195 at 2391.833 kb on + strand, within RR42_RS11195 at 2391.834 kb on - strand, within RR42_RS11195 at 2391.834 kb on - strand, within RR42_RS11195 at 2391.834 kb on - strand, within RR42_RS11195 at 2391.834 kb on - strand, within RR42_RS11195 at 2391.834 kb on - strand, within RR42_RS11195
Per-strain Table
Position Strand Gene LocusTag Fraction R2A with Vancomycin 0.5 mg/ml remove 2,388,587 + -0.7 2,388,587 + -0.9 2,388,588 - +0.4 2,388,588 - -0.2 2,388,689 + -0.9 2,388,847 + RR42_RS11185 0.30 -0.3 2,388,884 + RR42_RS11185 0.36 -1.4 2,388,885 - RR42_RS11185 0.36 +1.3 2,388,885 - RR42_RS11185 0.36 -0.0 2,388,914 + RR42_RS11185 0.40 -0.4 2,388,915 - RR42_RS11185 0.41 +1.1 2,388,915 - RR42_RS11185 0.41 +0.5 2,388,933 - RR42_RS11185 0.43 +1.3 2,388,973 + RR42_RS11185 0.50 -0.3 2,388,973 + RR42_RS11185 0.50 +1.5 2,388,974 - RR42_RS11185 0.50 -0.3 2,389,084 + RR42_RS11185 0.67 +0.5 2,389,115 + RR42_RS11185 0.71 +0.2 2,389,115 + RR42_RS11185 0.71 -0.8 2,389,116 - RR42_RS11185 0.72 +0.3 2,389,121 + RR42_RS11185 0.72 +1.5 2,389,122 - RR42_RS11185 0.73 -0.9 2,389,122 - RR42_RS11185 0.73 -0.7 2,389,182 - RR42_RS11185 0.82 +0.2 2,389,336 + +1.5 2,389,337 - -0.2 2,389,474 + -0.6 2,389,474 + -1.1 2,389,475 - +0.3 2,389,475 - +0.5 2,389,475 - -1.0 2,389,483 + +0.5 2,389,483 + -0.6 2,389,484 - +0.8 2,389,769 - RR42_RS11190 0.20 +0.4 2,389,783 + RR42_RS11190 0.21 -0.3 2,389,783 + RR42_RS11190 0.21 +0.4 2,389,784 - RR42_RS11190 0.21 -0.8 2,389,784 - RR42_RS11190 0.21 -0.0 2,389,784 - RR42_RS11190 0.21 -1.0 2,389,784 - RR42_RS11190 0.21 -0.6 2,389,785 + RR42_RS11190 0.21 -0.6 2,389,785 + RR42_RS11190 0.21 -0.5 2,389,785 + RR42_RS11190 0.21 -1.0 2,389,785 + RR42_RS11190 0.21 +0.2 2,389,785 + RR42_RS11190 0.21 +1.7 2,389,785 + RR42_RS11190 0.21 -1.5 2,389,785 + RR42_RS11190 0.21 -0.8 2,389,786 - RR42_RS11190 0.21 -0.1 2,389,786 - RR42_RS11190 0.21 -0.8 2,389,786 - RR42_RS11190 0.21 +0.5 2,389,827 + RR42_RS11190 0.24 +0.3 2,389,828 - RR42_RS11190 0.24 -0.3 2,389,828 - RR42_RS11190 0.24 +0.7 2,389,909 + RR42_RS11190 0.29 -0.5 2,389,910 - RR42_RS11190 0.29 +0.2 2,390,051 - RR42_RS11190 0.37 -0.3 2,390,210 + RR42_RS11190 0.47 +1.2 2,390,211 - RR42_RS11190 0.47 +0.1 2,390,211 - RR42_RS11190 0.47 -0.9 2,390,317 + RR42_RS11190 0.54 +1.8 2,390,317 + RR42_RS11190 0.54 -0.2 2,390,318 - RR42_RS11190 0.54 -0.9 2,390,318 - RR42_RS11190 0.54 +2.2 2,390,318 - RR42_RS11190 0.54 -1.7 2,390,318 - RR42_RS11190 0.54 -1.0 2,390,318 - RR42_RS11190 0.54 +1.5 2,390,318 - RR42_RS11190 0.54 +0.1 2,390,318 - RR42_RS11190 0.54 +1.2 2,390,318 - RR42_RS11190 0.54 -0.2 2,390,318 - RR42_RS11190 0.54 -0.2 2,390,320 - RR42_RS11190 0.54 +0.6 2,390,329 - RR42_RS11190 0.55 +0.1 2,390,386 + RR42_RS11190 0.58 -0.1 2,390,641 + RR42_RS11190 0.74 +0.9 2,391,009 + -0.5 2,391,236 + RR42_RS11195 0.11 -0.1 2,391,237 - RR42_RS11195 0.11 -1.3 2,391,336 - RR42_RS11195 0.19 +1.1 2,391,372 + RR42_RS11195 0.22 +1.1 2,391,372 + RR42_RS11195 0.22 -1.8 2,391,387 + RR42_RS11195 0.24 -0.1 2,391,387 + RR42_RS11195 0.24 -3.1 2,391,387 + RR42_RS11195 0.24 +0.7 2,391,387 + RR42_RS11195 0.24 +1.1 2,391,387 + RR42_RS11195 0.24 -0.9 2,391,388 - RR42_RS11195 0.24 +0.7 2,391,405 + RR42_RS11195 0.25 +0.4 2,391,405 + RR42_RS11195 0.25 +1.5 2,391,406 - RR42_RS11195 0.25 -0.0 2,391,407 + RR42_RS11195 0.25 -1.6 2,391,470 + RR42_RS11195 0.31 +0.5 2,391,470 + RR42_RS11195 0.31 +0.4 2,391,471 - RR42_RS11195 0.31 +0.2 2,391,588 + RR42_RS11195 0.40 -0.7 2,391,589 - RR42_RS11195 0.40 -0.3 2,391,827 + RR42_RS11195 0.60 -0.8 2,391,827 + RR42_RS11195 0.60 -0.2 2,391,827 + RR42_RS11195 0.60 +0.3 2,391,827 + RR42_RS11195 0.60 +0.4 2,391,828 - RR42_RS11195 0.60 +1.7 2,391,828 - RR42_RS11195 0.60 +0.5 2,391,833 + RR42_RS11195 0.60 +0.2 2,391,833 + RR42_RS11195 0.60 -0.2 2,391,833 + RR42_RS11195 0.60 +1.6 2,391,833 + RR42_RS11195 0.60 +0.2 2,391,834 - RR42_RS11195 0.61 +0.6 2,391,834 - RR42_RS11195 0.61 +1.2 2,391,834 - RR42_RS11195 0.61 -0.5 2,391,834 - RR42_RS11195 0.61 -0.5 2,391,834 - RR42_RS11195 0.61 -0.2
Or see this region's nucleotide sequence