Experiment: R2A with Cisplatin 0.001 mg/ml
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt RR42_RS31275 and RR42_RS31280 are separated by 16 nucleotides RR42_RS31280 and RR42_RS31285 are separated by 528 nucleotides RR42_RS31285 and RR42_RS31290 overlap by 96 nucleotides RR42_RS31290 and RR42_RS31295 are separated by 265 nucleotides
RR42_RS31275: RR42_RS31275 - Homogentisate 1,2-dioxygenase (EC 1.13.11.5) (from data) , at 2,391,461 to 2,392,810
_RS31275
RR42_RS31280: RR42_RS31280 - hypothetical protein, at 2,392,827 to 2,393,054
_RS31280
RR42_RS31285: RR42_RS31285 - XRE family transcriptional regulator, at 2,393,583 to 2,393,816
_RS31285
RR42_RS31290: RR42_RS31290 - XRE family transcriptional regulator, at 2,393,721 to 2,393,975
_RS31290
RR42_RS31295: RR42_RS31295 - XRE family transcriptional regulator, at 2,394,241 to 2,394,849
_RS31295
Position (kb)
2393
2394 Strain fitness (log2 ratio)
-3
-2
-1
0
1
2
3 at 2392.744 kb on - strand at 2392.828 kb on + strand at 2392.828 kb on + strand at 2392.829 kb on - strand at 2392.829 kb on - strand at 2392.829 kb on - strand at 2393.008 kb on + strand, within RR42_RS31280 at 2393.008 kb on + strand, within RR42_RS31280 at 2393.008 kb on + strand, within RR42_RS31280 at 2393.009 kb on - strand, within RR42_RS31280 at 2393.009 kb on - strand, within RR42_RS31280 at 2393.009 kb on - strand, within RR42_RS31280 at 2393.043 kb on - strand at 2393.179 kb on + strand at 2393.209 kb on + strand at 2393.210 kb on - strand at 2393.219 kb on + strand at 2393.253 kb on + strand at 2393.253 kb on + strand at 2393.253 kb on + strand at 2393.253 kb on + strand at 2393.254 kb on - strand at 2393.254 kb on - strand at 2393.261 kb on + strand at 2393.261 kb on + strand at 2393.262 kb on - strand at 2393.262 kb on - strand at 2393.262 kb on - strand at 2393.262 kb on - strand at 2393.262 kb on - strand at 2393.262 kb on - strand at 2393.262 kb on - strand at 2393.262 kb on - strand at 2393.656 kb on - strand, within RR42_RS31285 at 2393.730 kb on - strand at 2393.730 kb on - strand at 2393.852 kb on - strand, within RR42_RS31290 at 2393.852 kb on - strand, within RR42_RS31290 at 2393.966 kb on + strand at 2393.967 kb on - strand at 2394.028 kb on + strand at 2394.028 kb on + strand at 2394.029 kb on - strand at 2394.049 kb on + strand at 2394.049 kb on + strand at 2394.050 kb on - strand at 2394.050 kb on - strand at 2394.050 kb on - strand at 2394.053 kb on + strand at 2394.054 kb on - strand at 2394.109 kb on + strand at 2394.109 kb on + strand at 2394.109 kb on + strand at 2394.110 kb on - strand at 2394.110 kb on - strand at 2394.110 kb on - strand at 2394.120 kb on + strand at 2394.121 kb on - strand at 2394.129 kb on + strand at 2394.129 kb on + strand at 2394.129 kb on + strand at 2394.141 kb on - strand at 2394.141 kb on - strand at 2394.178 kb on + strand at 2394.178 kb on + strand at 2394.258 kb on + strand at 2394.326 kb on + strand, within RR42_RS31295 at 2394.370 kb on + strand, within RR42_RS31295 at 2394.508 kb on + strand, within RR42_RS31295 at 2394.508 kb on + strand, within RR42_RS31295 at 2394.508 kb on + strand, within RR42_RS31295 at 2394.508 kb on + strand, within RR42_RS31295 at 2394.508 kb on + strand, within RR42_RS31295 at 2394.574 kb on + strand, within RR42_RS31295 at 2394.751 kb on + strand, within RR42_RS31295 at 2394.751 kb on + strand, within RR42_RS31295 at 2394.752 kb on - strand, within RR42_RS31295 at 2394.759 kb on - strand, within RR42_RS31295 at 2394.759 kb on - strand, within RR42_RS31295 at 2394.759 kb on - strand, within RR42_RS31295 at 2394.759 kb on - strand, within RR42_RS31295 at 2394.759 kb on - strand, within RR42_RS31295 at 2394.848 kb on - strand at 2394.848 kb on - strand
Per-strain Table
Position Strand Gene LocusTag Fraction R2A with Cisplatin 0.001 mg/ml remove 2,392,744 - +0.4 2,392,828 + -0.7 2,392,828 + -0.0 2,392,829 - +0.9 2,392,829 - +0.4 2,392,829 - +0.7 2,393,008 + RR42_RS31280 0.79 -0.1 2,393,008 + RR42_RS31280 0.79 +3.5 2,393,008 + RR42_RS31280 0.79 +0.3 2,393,009 - RR42_RS31280 0.80 +0.2 2,393,009 - RR42_RS31280 0.80 +0.3 2,393,009 - RR42_RS31280 0.80 -1.2 2,393,043 - +0.7 2,393,179 + -1.4 2,393,209 + +0.4 2,393,210 - -0.2 2,393,219 + -0.8 2,393,253 + +0.3 2,393,253 + +0.4 2,393,253 + -0.4 2,393,253 + -0.0 2,393,254 - +0.9 2,393,254 - +0.2 2,393,261 + +0.7 2,393,261 + -0.4 2,393,262 - +0.2 2,393,262 - +1.3 2,393,262 - +0.5 2,393,262 - -1.1 2,393,262 - +0.6 2,393,262 - -0.4 2,393,262 - -0.4 2,393,262 - -0.8 2,393,656 - RR42_RS31285 0.31 -0.1 2,393,730 - -1.7 2,393,730 - -1.9 2,393,852 - RR42_RS31290 0.51 +0.9 2,393,852 - RR42_RS31290 0.51 -1.1 2,393,966 + -2.3 2,393,967 - -0.7 2,394,028 + -0.4 2,394,028 + +0.4 2,394,029 - +0.5 2,394,049 + -0.9 2,394,049 + +0.3 2,394,050 - -0.6 2,394,050 - +0.5 2,394,050 - -0.4 2,394,053 + -1.1 2,394,054 - +0.0 2,394,109 + +0.9 2,394,109 + +0.2 2,394,109 + -3.1 2,394,110 - -0.1 2,394,110 - +2.1 2,394,110 - -0.7 2,394,120 + -0.8 2,394,121 - +0.6 2,394,129 + -1.3 2,394,129 + -2.8 2,394,129 + -0.7 2,394,141 - -1.4 2,394,141 - -0.1 2,394,178 + +0.3 2,394,178 + -1.8 2,394,258 + -0.1 2,394,326 + RR42_RS31295 0.14 -0.9 2,394,370 + RR42_RS31295 0.21 -0.7 2,394,508 + RR42_RS31295 0.44 +0.1 2,394,508 + RR42_RS31295 0.44 -0.2 2,394,508 + RR42_RS31295 0.44 -0.2 2,394,508 + RR42_RS31295 0.44 -0.3 2,394,508 + RR42_RS31295 0.44 +0.9 2,394,574 + RR42_RS31295 0.55 -0.5 2,394,751 + RR42_RS31295 0.84 +0.8 2,394,751 + RR42_RS31295 0.84 +1.1 2,394,752 - RR42_RS31295 0.84 -0.2 2,394,759 - RR42_RS31295 0.85 -0.4 2,394,759 - RR42_RS31295 0.85 +0.2 2,394,759 - RR42_RS31295 0.85 +0.3 2,394,759 - RR42_RS31295 0.85 +0.6 2,394,759 - RR42_RS31295 0.85 -0.4 2,394,848 - +0.4 2,394,848 - -0.9
Or see this region's nucleotide sequence