Experiment: BHIS with Simvastatin 30 uM
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt BT2422 and BT2423 are separated by 115 nucleotides BT2423 and BT2424 are separated by 16 nucleotides BT2424 and BT2425 are separated by 18 nucleotides
BT2422: BT2422 - conserved hypothetical protein (NCBI ptt file), at 3,025,126 to 3,025,872
BT2422
BT2423: BT2423 - K+-transporting ATPase C chain (NCBI ptt file), at 3,025,988 to 3,026,557
BT2423
BT2424: BT2424 - K+-transporting ATPase B chain (NCBI ptt file), at 3,026,574 to 3,028,607
BT2424
BT2425: BT2425 - K+-transporting ATPase A chain (NCBI ptt file), at 3,028,626 to 3,030,332
BT2425
Position (kb)
3026
3027
3028
3029 Strain fitness (log2 ratio)
-4
-3
-2
-1
0
1
2 at 3025.606 kb on - strand, within BT2422 at 3025.607 kb on + strand, within BT2422 at 3025.748 kb on + strand, within BT2422 at 3025.748 kb on + strand, within BT2422 at 3025.816 kb on + strand at 3025.930 kb on - strand at 3025.947 kb on + strand at 3025.947 kb on + strand at 3025.990 kb on - strand at 3026.009 kb on + strand at 3026.010 kb on - strand at 3026.010 kb on - strand at 3026.145 kb on + strand, within BT2423 at 3026.145 kb on + strand, within BT2423 at 3026.146 kb on - strand, within BT2423 at 3026.164 kb on + strand, within BT2423 at 3026.164 kb on + strand, within BT2423 at 3026.164 kb on + strand, within BT2423 at 3026.165 kb on - strand, within BT2423 at 3026.167 kb on + strand, within BT2423 at 3026.168 kb on - strand, within BT2423 at 3026.321 kb on - strand, within BT2423 at 3026.332 kb on - strand, within BT2423 at 3026.368 kb on - strand, within BT2423 at 3026.371 kb on + strand, within BT2423 at 3026.452 kb on + strand at 3026.452 kb on + strand, within BT2423 at 3026.453 kb on - strand, within BT2423 at 3026.493 kb on + strand, within BT2423 at 3026.529 kb on - strand at 3026.529 kb on - strand at 3026.561 kb on + strand at 3026.590 kb on - strand at 3026.609 kb on + strand at 3026.640 kb on + strand at 3026.648 kb on - strand at 3026.696 kb on - strand at 3026.736 kb on - strand at 3026.739 kb on - strand at 3026.784 kb on - strand, within BT2424 at 3026.831 kb on + strand, within BT2424 at 3027.002 kb on + strand, within BT2424 at 3027.019 kb on - strand, within BT2424 at 3027.110 kb on + strand, within BT2424 at 3027.110 kb on + strand, within BT2424 at 3027.111 kb on - strand, within BT2424 at 3027.112 kb on + strand, within BT2424 at 3027.146 kb on + strand, within BT2424 at 3027.146 kb on + strand, within BT2424 at 3027.178 kb on + strand, within BT2424 at 3027.332 kb on + strand, within BT2424 at 3027.411 kb on - strand, within BT2424 at 3027.494 kb on + strand at 3027.531 kb on - strand, within BT2424 at 3027.536 kb on + strand, within BT2424 at 3027.665 kb on + strand, within BT2424 at 3027.666 kb on - strand, within BT2424 at 3027.684 kb on - strand, within BT2424 at 3027.710 kb on + strand, within BT2424 at 3027.711 kb on - strand, within BT2424 at 3027.716 kb on + strand, within BT2424 at 3027.875 kb on + strand, within BT2424 at 3027.876 kb on - strand, within BT2424 at 3027.876 kb on - strand, within BT2424 at 3027.997 kb on - strand, within BT2424 at 3028.051 kb on - strand, within BT2424 at 3028.056 kb on + strand, within BT2424 at 3028.056 kb on + strand, within BT2424 at 3028.080 kb on - strand, within BT2424 at 3028.179 kb on + strand, within BT2424 at 3028.239 kb on + strand, within BT2424 at 3028.255 kb on - strand, within BT2424 at 3028.255 kb on - strand, within BT2424 at 3028.386 kb on - strand, within BT2424 at 3028.407 kb on + strand at 3028.407 kb on + strand at 3028.408 kb on - strand at 3028.450 kb on + strand at 3028.451 kb on - strand at 3028.495 kb on + strand at 3028.496 kb on - strand at 3028.496 kb on - strand at 3028.496 kb on - strand at 3028.560 kb on + strand at 3028.561 kb on - strand at 3028.563 kb on - strand at 3028.617 kb on - strand at 3028.652 kb on + strand at 3028.814 kb on + strand, within BT2425 at 3028.815 kb on - strand, within BT2425 at 3028.835 kb on + strand, within BT2425 at 3028.840 kb on - strand, within BT2425 at 3028.844 kb on + strand, within BT2425 at 3028.868 kb on - strand, within BT2425 at 3028.871 kb on + strand, within BT2425 at 3028.922 kb on + strand, within BT2425 at 3028.922 kb on + strand, within BT2425 at 3028.922 kb on + strand, within BT2425 at 3028.922 kb on + strand, within BT2425 at 3028.924 kb on + strand, within BT2425 at 3029.007 kb on + strand, within BT2425 at 3029.007 kb on + strand, within BT2425 at 3029.007 kb on + strand, within BT2425 at 3029.008 kb on - strand, within BT2425 at 3029.011 kb on + strand, within BT2425 at 3029.011 kb on + strand, within BT2425 at 3029.011 kb on + strand, within BT2425 at 3029.011 kb on + strand, within BT2425 at 3029.011 kb on + strand, within BT2425 at 3029.011 kb on + strand, within BT2425 at 3029.012 kb on - strand, within BT2425 at 3029.012 kb on - strand, within BT2425 at 3029.015 kb on + strand, within BT2425 at 3029.018 kb on - strand, within BT2425 at 3029.075 kb on + strand, within BT2425 at 3029.133 kb on + strand, within BT2425 at 3029.150 kb on + strand, within BT2425 at 3029.151 kb on - strand, within BT2425 at 3029.151 kb on - strand, within BT2425 at 3029.151 kb on - strand, within BT2425 at 3029.165 kb on + strand, within BT2425 at 3029.174 kb on + strand, within BT2425 at 3029.194 kb on - strand, within BT2425 at 3029.216 kb on + strand, within BT2425 at 3029.216 kb on + strand, within BT2425 at 3029.219 kb on + strand, within BT2425 at 3029.246 kb on + strand, within BT2425 at 3029.264 kb on + strand, within BT2425 at 3029.264 kb on + strand, within BT2425 at 3029.264 kb on + strand, within BT2425 at 3029.265 kb on - strand, within BT2425 at 3029.276 kb on + strand, within BT2425 at 3029.276 kb on + strand, within BT2425 at 3029.448 kb on + strand, within BT2425 at 3029.507 kb on + strand, within BT2425 at 3029.509 kb on + strand, within BT2425 at 3029.509 kb on + strand, within BT2425 at 3029.510 kb on - strand, within BT2425 at 3029.552 kb on + strand, within BT2425 at 3029.553 kb on - strand, within BT2425 at 3029.571 kb on - strand, within BT2425 at 3029.582 kb on - strand, within BT2425
Per-strain Table
Position Strand Gene LocusTag Fraction BHIS with Simvastatin 30 uM remove 3,025,606 - BT2422 0.64 -1.5 3,025,607 + BT2422 0.64 +1.6 3,025,748 + BT2422 0.83 -0.6 3,025,748 + BT2422 0.83 -0.8 3,025,816 + -0.0 3,025,930 - -2.0 3,025,947 + -1.6 3,025,947 + -0.8 3,025,990 - +0.0 3,026,009 + -1.2 3,026,010 - -0.5 3,026,010 - -2.0 3,026,145 + BT2423 0.28 -1.7 3,026,145 + BT2423 0.28 -1.8 3,026,146 - BT2423 0.28 +0.2 3,026,164 + BT2423 0.31 +0.4 3,026,164 + BT2423 0.31 +0.2 3,026,164 + BT2423 0.31 +0.9 3,026,165 - BT2423 0.31 -3.0 3,026,167 + BT2423 0.31 +1.0 3,026,168 - BT2423 0.32 -0.9 3,026,321 - BT2423 0.58 -3.0 3,026,332 - BT2423 0.60 -2.8 3,026,368 - BT2423 0.67 -1.1 3,026,371 + BT2423 0.67 -0.9 3,026,452 + -0.4 3,026,452 + BT2423 0.81 +0.6 3,026,453 - BT2423 0.82 -1.4 3,026,493 + BT2423 0.89 +0.7 3,026,529 - -2.8 3,026,529 - -2.1 3,026,561 + -1.0 3,026,590 - -2.3 3,026,609 + -2.1 3,026,640 + -0.8 3,026,648 - +0.6 3,026,696 - -1.6 3,026,736 - -1.2 3,026,739 - -1.6 3,026,784 - BT2424 0.10 -3.9 3,026,831 + BT2424 0.13 -1.0 3,027,002 + BT2424 0.21 +0.6 3,027,019 - BT2424 0.22 -1.2 3,027,110 + BT2424 0.26 -1.9 3,027,110 + BT2424 0.26 -2.4 3,027,111 - BT2424 0.26 +0.6 3,027,112 + BT2424 0.26 -3.0 3,027,146 + BT2424 0.28 -2.0 3,027,146 + BT2424 0.28 -0.4 3,027,178 + BT2424 0.30 -1.8 3,027,332 + BT2424 0.37 -1.8 3,027,411 - BT2424 0.41 -1.2 3,027,494 + -1.4 3,027,531 - BT2424 0.47 -0.0 3,027,536 + BT2424 0.47 -1.6 3,027,665 + BT2424 0.54 -2.3 3,027,666 - BT2424 0.54 -1.6 3,027,684 - BT2424 0.55 -1.8 3,027,710 + BT2424 0.56 -0.4 3,027,711 - BT2424 0.56 -3.4 3,027,716 + BT2424 0.56 -1.8 3,027,875 + BT2424 0.64 -1.0 3,027,876 - BT2424 0.64 -2.0 3,027,876 - BT2424 0.64 -2.0 3,027,997 - BT2424 0.70 -1.1 3,028,051 - BT2424 0.73 -2.5 3,028,056 + BT2424 0.73 -1.8 3,028,056 + BT2424 0.73 -1.0 3,028,080 - BT2424 0.74 +0.4 3,028,179 + BT2424 0.79 -3.1 3,028,239 + BT2424 0.82 -0.3 3,028,255 - BT2424 0.83 +0.9 3,028,255 - BT2424 0.83 -1.2 3,028,386 - BT2424 0.89 -2.7 3,028,407 + -1.0 3,028,407 + +0.6 3,028,408 - -1.0 3,028,450 + +0.6 3,028,451 - -0.0 3,028,495 + -2.4 3,028,496 - -0.8 3,028,496 - -1.2 3,028,496 - -0.7 3,028,560 + -0.4 3,028,561 - -1.9 3,028,563 - +0.3 3,028,617 - -2.8 3,028,652 + -0.9 3,028,814 + BT2425 0.11 -3.2 3,028,815 - BT2425 0.11 -0.4 3,028,835 + BT2425 0.12 -0.5 3,028,840 - BT2425 0.13 -1.2 3,028,844 + BT2425 0.13 -1.7 3,028,868 - BT2425 0.14 -1.8 3,028,871 + BT2425 0.14 -0.0 3,028,922 + BT2425 0.17 -2.5 3,028,922 + BT2425 0.17 -0.4 3,028,922 + BT2425 0.17 -1.0 3,028,922 + BT2425 0.17 -0.8 3,028,924 + BT2425 0.17 -1.8 3,029,007 + BT2425 0.22 -0.0 3,029,007 + BT2425 0.22 -2.4 3,029,007 + BT2425 0.22 +0.4 3,029,008 - BT2425 0.22 -0.8 3,029,011 + BT2425 0.23 -0.4 3,029,011 + BT2425 0.23 -1.0 3,029,011 + BT2425 0.23 +0.8 3,029,011 + BT2425 0.23 +0.2 3,029,011 + BT2425 0.23 -2.8 3,029,011 + BT2425 0.23 -0.1 3,029,012 - BT2425 0.23 -0.0 3,029,012 - BT2425 0.23 +1.2 3,029,015 + BT2425 0.23 -1.4 3,029,018 - BT2425 0.23 -2.4 3,029,075 + BT2425 0.26 -0.8 3,029,133 + BT2425 0.30 +0.7 3,029,150 + BT2425 0.31 -0.4 3,029,151 - BT2425 0.31 -0.8 3,029,151 - BT2425 0.31 -0.4 3,029,151 - BT2425 0.31 +0.2 3,029,165 + BT2425 0.32 -1.9 3,029,174 + BT2425 0.32 -2.4 3,029,194 - BT2425 0.33 -3.9 3,029,216 + BT2425 0.35 -1.4 3,029,216 + BT2425 0.35 +0.2 3,029,219 + BT2425 0.35 -1.4 3,029,246 + BT2425 0.36 -1.9 3,029,264 + BT2425 0.37 -0.4 3,029,264 + BT2425 0.37 -1.0 3,029,264 + BT2425 0.37 -4.2 3,029,265 - BT2425 0.37 -2.1 3,029,276 + BT2425 0.38 -1.4 3,029,276 + BT2425 0.38 +2.3 3,029,448 + BT2425 0.48 -0.4 3,029,507 + BT2425 0.52 -0.8 3,029,509 + BT2425 0.52 -1.7 3,029,509 + BT2425 0.52 -1.0 3,029,510 - BT2425 0.52 -1.6 3,029,552 + BT2425 0.54 +0.5 3,029,553 - BT2425 0.54 +1.6 3,029,571 - BT2425 0.55 -0.0 3,029,582 - BT2425 0.56 -1.0
Or see this region's nucleotide sequence