Experiment: Lacto-N-tetraose 10 mg/mL (C)
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt HMPREF1058_RS06185 and HMPREF1058_RS06180 are separated by 1 nucleotides HMPREF1058_RS06180 and HMPREF1058_RS06175 are separated by 164 nucleotides HMPREF1058_RS06175 and HMPREF1058_RS06170 are separated by 9 nucleotides HMPREF1058_RS06170 and HMPREF1058_RS06165 are separated by 41 nucleotides
HMPREF1058_RS06185: HMPREF1058_RS06185 - ATP-binding cassette domain-containing protein, at 540,291 to 541,049
_RS06185
HMPREF1058_RS06180: HMPREF1058_RS06180 - bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE, at 541,051 to 541,662
_RS06180
HMPREF1058_RS06175: HMPREF1058_RS06175 - imidazole glycerol phosphate synthase subunit HisF, at 541,827 to 542,582
_RS06175
HMPREF1058_RS06170: HMPREF1058_RS06170 - 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino]imidazole-4- carboxamide isomerase, at 542,592 to 543,311
_RS06170
HMPREF1058_RS06165: HMPREF1058_RS06165 - imidazole glycerol phosphate synthase subunit HisH, at 543,353 to 543,943
_RS06165
Position (kb)
541
542
543 Strain fitness (log2 ratio)
-4
-3
-2
-1
0
1
2 at 540.876 kb on + strand, within HMPREF1058_RS06185 at 540.877 kb on - strand, within HMPREF1058_RS06185 at 540.877 kb on - strand, within HMPREF1058_RS06185 at 540.877 kb on - strand, within HMPREF1058_RS06185 at 540.975 kb on + strand at 540.993 kb on + strand at 541.010 kb on + strand at 541.011 kb on - strand at 541.012 kb on + strand at 541.014 kb on + strand at 541.014 kb on + strand at 541.015 kb on - strand at 541.136 kb on - strand, within HMPREF1058_RS06180 at 541.136 kb on - strand, within HMPREF1058_RS06180 at 541.136 kb on - strand, within HMPREF1058_RS06180 at 541.136 kb on - strand, within HMPREF1058_RS06180 at 541.149 kb on - strand, within HMPREF1058_RS06180 at 541.169 kb on + strand, within HMPREF1058_RS06180 at 541.328 kb on - strand, within HMPREF1058_RS06180 at 541.377 kb on + strand, within HMPREF1058_RS06180 at 541.377 kb on + strand, within HMPREF1058_RS06180 at 541.378 kb on - strand, within HMPREF1058_RS06180 at 541.396 kb on + strand, within HMPREF1058_RS06180 at 541.396 kb on + strand, within HMPREF1058_RS06180 at 541.397 kb on - strand, within HMPREF1058_RS06180 at 541.414 kb on + strand, within HMPREF1058_RS06180 at 541.415 kb on - strand, within HMPREF1058_RS06180 at 541.615 kb on + strand at 541.616 kb on - strand at 541.683 kb on + strand at 541.684 kb on - strand at 541.697 kb on + strand at 541.697 kb on + strand at 541.698 kb on - strand at 541.828 kb on + strand at 541.831 kb on - strand at 541.842 kb on - strand at 542.129 kb on - strand, within HMPREF1058_RS06175 at 542.335 kb on - strand, within HMPREF1058_RS06175 at 542.336 kb on + strand, within HMPREF1058_RS06175 at 542.336 kb on + strand, within HMPREF1058_RS06175 at 542.337 kb on - strand, within HMPREF1058_RS06175 at 542.337 kb on - strand, within HMPREF1058_RS06175 at 542.467 kb on + strand, within HMPREF1058_RS06175 at 542.471 kb on + strand, within HMPREF1058_RS06175 at 542.471 kb on + strand, within HMPREF1058_RS06175 at 542.529 kb on + strand at 542.594 kb on - strand at 542.594 kb on - strand at 542.635 kb on + strand at 542.697 kb on + strand, within HMPREF1058_RS06170 at 542.815 kb on - strand, within HMPREF1058_RS06170 at 542.815 kb on - strand, within HMPREF1058_RS06170 at 542.838 kb on - strand, within HMPREF1058_RS06170 at 542.841 kb on - strand, within HMPREF1058_RS06170 at 542.842 kb on + strand, within HMPREF1058_RS06170 at 542.843 kb on - strand, within HMPREF1058_RS06170 at 543.010 kb on - strand, within HMPREF1058_RS06170 at 543.228 kb on + strand, within HMPREF1058_RS06170 at 543.229 kb on - strand, within HMPREF1058_RS06170 at 543.244 kb on + strand at 543.300 kb on + strand at 543.301 kb on - strand at 543.301 kb on - strand at 543.315 kb on + strand at 543.316 kb on - strand at 543.328 kb on - strand at 543.328 kb on - strand at 543.335 kb on + strand at 543.340 kb on - strand at 543.340 kb on - strand at 543.342 kb on - strand at 543.467 kb on - strand, within HMPREF1058_RS06165 at 543.467 kb on - strand, within HMPREF1058_RS06165 at 543.507 kb on + strand, within HMPREF1058_RS06165 at 543.508 kb on - strand, within HMPREF1058_RS06165 at 543.519 kb on - strand, within HMPREF1058_RS06165 at 543.519 kb on - strand, within HMPREF1058_RS06165
Per-strain Table
Position Strand Gene LocusTag Fraction Lacto-N-tetraose 10 mg/mL (C) remove 540,876 + HMPREF1058_RS06185 0.77 -0.3 540,877 - HMPREF1058_RS06185 0.77 -0.4 540,877 - HMPREF1058_RS06185 0.77 -1.6 540,877 - HMPREF1058_RS06185 0.77 +0.8 540,975 + -0.8 540,993 + -1.0 541,010 + -0.3 541,011 - -1.6 541,012 + -0.1 541,014 + -0.2 541,014 + +0.0 541,015 - +1.4 541,136 - HMPREF1058_RS06180 0.14 -0.4 541,136 - HMPREF1058_RS06180 0.14 -2.2 541,136 - HMPREF1058_RS06180 0.14 -2.4 541,136 - HMPREF1058_RS06180 0.14 -1.4 541,149 - HMPREF1058_RS06180 0.16 +1.6 541,169 + HMPREF1058_RS06180 0.19 -0.5 541,328 - HMPREF1058_RS06180 0.45 -3.2 541,377 + HMPREF1058_RS06180 0.53 +1.2 541,377 + HMPREF1058_RS06180 0.53 -1.3 541,378 - HMPREF1058_RS06180 0.53 -0.5 541,396 + HMPREF1058_RS06180 0.56 +1.8 541,396 + HMPREF1058_RS06180 0.56 -0.8 541,397 - HMPREF1058_RS06180 0.57 -1.2 541,414 + HMPREF1058_RS06180 0.59 +0.7 541,415 - HMPREF1058_RS06180 0.59 -0.5 541,615 + -0.8 541,616 - -3.2 541,683 + -1.8 541,684 - -0.0 541,697 + -0.7 541,697 + +0.2 541,698 - -0.2 541,828 + -4.2 541,831 - -0.5 541,842 - -1.4 542,129 - HMPREF1058_RS06175 0.40 -1.4 542,335 - HMPREF1058_RS06175 0.67 -0.9 542,336 + HMPREF1058_RS06175 0.67 +0.9 542,336 + HMPREF1058_RS06175 0.67 +2.4 542,337 - HMPREF1058_RS06175 0.67 -1.2 542,337 - HMPREF1058_RS06175 0.67 +2.0 542,467 + HMPREF1058_RS06175 0.85 -3.1 542,471 + HMPREF1058_RS06175 0.85 -2.0 542,471 + HMPREF1058_RS06175 0.85 +0.1 542,529 + -1.0 542,594 - +1.4 542,594 - +0.4 542,635 + -0.2 542,697 + HMPREF1058_RS06170 0.15 -1.2 542,815 - HMPREF1058_RS06170 0.31 -0.3 542,815 - HMPREF1058_RS06170 0.31 -3.3 542,838 - HMPREF1058_RS06170 0.34 -3.8 542,841 - HMPREF1058_RS06170 0.35 -2.0 542,842 + HMPREF1058_RS06170 0.35 +0.5 542,843 - HMPREF1058_RS06170 0.35 -2.0 543,010 - HMPREF1058_RS06170 0.58 -1.0 543,228 + HMPREF1058_RS06170 0.88 -0.2 543,229 - HMPREF1058_RS06170 0.88 -1.5 543,244 + -1.4 543,300 + +0.1 543,301 - -1.1 543,301 - -2.1 543,315 + -0.2 543,316 - -1.4 543,328 - +0.7 543,328 - +0.7 543,335 + -1.0 543,340 - +1.4 543,340 - +0.4 543,342 - -0.4 543,467 - HMPREF1058_RS06165 0.19 -0.4 543,467 - HMPREF1058_RS06165 0.19 -2.2 543,507 + HMPREF1058_RS06165 0.26 +0.9 543,508 - HMPREF1058_RS06165 0.26 -1.3 543,519 - HMPREF1058_RS06165 0.28 -0.3 543,519 - HMPREF1058_RS06165 0.28 +0.1
Or see this region's nucleotide sequence