Experiment: BHIS with Simvastatin 30 uM
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt BT1268 and BT1269 are separated by 10 nucleotides BT1269 and BT1270 are separated by 195 nucleotides
BT1268: BT1268 - transporter, AcrB/D/F family (NCBI ptt file), at 1,575,322 to 1,578,354
BT1268
BT1269: BT1269 - component of multidrug efflux system (NCBI ptt file), at 1,578,365 to 1,579,435
BT1269
BT1270: BT1270 - putative Na+/H+ antiporter (NCBI ptt file), at 1,579,631 to 1,580,932
BT1270
Position (kb)
1578
1579
1580 Strain fitness (log2 ratio)
-3
-2
-1
0
1
2 at 1577.391 kb on - strand, within BT1268 at 1577.493 kb on + strand, within BT1268 at 1577.505 kb on + strand, within BT1268 at 1577.620 kb on - strand, within BT1268 at 1577.655 kb on + strand, within BT1268 at 1577.822 kb on + strand, within BT1268 at 1577.987 kb on + strand, within BT1268 at 1578.001 kb on + strand, within BT1268 at 1578.074 kb on + strand at 1578.074 kb on + strand at 1578.075 kb on - strand at 1578.142 kb on + strand at 1578.158 kb on - strand at 1578.270 kb on - strand at 1578.343 kb on + strand at 1578.354 kb on + strand at 1578.366 kb on + strand at 1578.407 kb on - strand at 1578.569 kb on + strand, within BT1269 at 1578.573 kb on + strand, within BT1269 at 1578.573 kb on + strand, within BT1269 at 1578.854 kb on - strand, within BT1269 at 1578.858 kb on + strand, within BT1269 at 1578.858 kb on + strand, within BT1269 at 1578.858 kb on + strand, within BT1269 at 1578.859 kb on - strand, within BT1269 at 1578.859 kb on - strand, within BT1269 at 1578.950 kb on + strand, within BT1269 at 1578.952 kb on + strand, within BT1269 at 1578.952 kb on + strand, within BT1269 at 1578.953 kb on - strand, within BT1269 at 1578.974 kb on - strand, within BT1269 at 1579.011 kb on + strand, within BT1269 at 1579.084 kb on - strand, within BT1269 at 1579.125 kb on + strand, within BT1269 at 1579.129 kb on + strand, within BT1269 at 1579.187 kb on - strand, within BT1269 at 1579.187 kb on - strand, within BT1269 at 1579.285 kb on + strand, within BT1269 at 1579.448 kb on + strand at 1579.448 kb on + strand at 1579.449 kb on - strand at 1579.578 kb on + strand at 1579.579 kb on - strand at 1579.581 kb on - strand at 1579.611 kb on - strand at 1579.612 kb on + strand at 1579.613 kb on - strand at 1579.613 kb on - strand at 1579.651 kb on + strand at 1579.653 kb on + strand at 1579.654 kb on - strand at 1579.743 kb on - strand at 1579.862 kb on - strand, within BT1270 at 1579.961 kb on - strand, within BT1270 at 1580.037 kb on + strand, within BT1270 at 1580.113 kb on - strand, within BT1270 at 1580.161 kb on - strand, within BT1270 at 1580.239 kb on - strand, within BT1270 at 1580.286 kb on + strand, within BT1270 at 1580.286 kb on + strand, within BT1270 at 1580.344 kb on + strand, within BT1270 at 1580.345 kb on - strand, within BT1270 at 1580.346 kb on + strand, within BT1270 at 1580.347 kb on - strand, within BT1270 at 1580.400 kb on + strand, within BT1270
Per-strain Table
Position Strand Gene LocusTag Fraction BHIS with Simvastatin 30 uM remove 1,577,391 - BT1268 0.68 -2.5 1,577,493 + BT1268 0.72 -0.6 1,577,505 + BT1268 0.72 -1.2 1,577,620 - BT1268 0.76 -0.2 1,577,655 + BT1268 0.77 -2.9 1,577,822 + BT1268 0.82 -0.2 1,577,987 + BT1268 0.88 -0.2 1,578,001 + BT1268 0.88 +1.0 1,578,074 + -2.5 1,578,074 + -0.2 1,578,075 - -2.2 1,578,142 + -0.2 1,578,158 - +0.4 1,578,270 - -1.8 1,578,343 + -0.2 1,578,354 + -3.5 1,578,366 + -2.2 1,578,407 - -2.2 1,578,569 + BT1269 0.19 -0.2 1,578,573 + BT1269 0.19 -0.2 1,578,573 + BT1269 0.19 -0.2 1,578,854 - BT1269 0.46 -1.2 1,578,858 + BT1269 0.46 -1.2 1,578,858 + BT1269 0.46 -1.8 1,578,858 + BT1269 0.46 -0.2 1,578,859 - BT1269 0.46 -2.5 1,578,859 - BT1269 0.46 -3.4 1,578,950 + BT1269 0.55 -2.2 1,578,952 + BT1269 0.55 -2.2 1,578,952 + BT1269 0.55 -1.8 1,578,953 - BT1269 0.55 -0.2 1,578,974 - BT1269 0.57 -0.2 1,579,011 + BT1269 0.60 -3.5 1,579,084 - BT1269 0.67 -3.2 1,579,125 + BT1269 0.71 -1.2 1,579,129 + BT1269 0.71 -0.5 1,579,187 - BT1269 0.77 -1.2 1,579,187 - BT1269 0.77 -2.5 1,579,285 + BT1269 0.86 -2.2 1,579,448 + -1.8 1,579,448 + +1.9 1,579,449 - -0.2 1,579,578 + -0.9 1,579,579 - -1.2 1,579,581 - -0.2 1,579,611 - -0.2 1,579,612 + -1.2 1,579,613 - -0.2 1,579,613 - -1.8 1,579,651 + -0.2 1,579,653 + -0.2 1,579,654 - -1.2 1,579,743 - -1.8 1,579,862 - BT1270 0.18 -0.2 1,579,961 - BT1270 0.25 -1.2 1,580,037 + BT1270 0.31 -0.2 1,580,113 - BT1270 0.37 -0.2 1,580,161 - BT1270 0.41 -0.2 1,580,239 - BT1270 0.47 -1.2 1,580,286 + BT1270 0.50 -1.8 1,580,286 + BT1270 0.50 -0.2 1,580,344 + BT1270 0.55 -0.2 1,580,345 - BT1270 0.55 -2.2 1,580,346 + BT1270 0.55 -1.2 1,580,347 - BT1270 0.55 -0.2 1,580,400 + BT1270 0.59 -0.2
Or see this region's nucleotide sequence