Strain Fitness in Bifidobacterium breve UCC2003 around BBR_RS14615

Experiment: Recovery broth with Lacidipine 0.4 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntBBR_RS14610 and BBR_RS14615 are separated by 21 nucleotidesBBR_RS14615 and BBR_RS14620 are separated by 81 nucleotides BBR_RS14610: BBR_RS14610 - DNA-binding response regulator, at 1,052,467 to 1,053,273 _RS14610 BBR_RS14615: BBR_RS14615 - histidine kinase, at 1,053,295 to 1,055,763 _RS14615 BBR_RS14620: BBR_RS14620 - proline iminopeptidase, at 1,055,845 to 1,057,323 _RS14620 Position (kb) 1053 1054 1055 1056Strain fitness (log2 ratio) -3 -2 -1 0 1at 1052.364 kb on + strandat 1052.465 kb on + strandat 1052.470 kb on + strandat 1052.502 kb on - strandat 1052.520 kb on - strandat 1052.544 kb on - strandat 1052.735 kb on + strand, within BBR_RS14610at 1052.908 kb on - strand, within BBR_RS14610at 1052.919 kb on + strand, within BBR_RS14610at 1053.013 kb on + strand, within BBR_RS14610at 1053.013 kb on + strand, within BBR_RS14610at 1053.014 kb on - strand, within BBR_RS14610at 1053.194 kb on + strandat 1053.228 kb on - strandat 1053.269 kb on + strandat 1053.277 kb on + strandat 1053.284 kb on - strandat 1053.318 kb on + strandat 1053.326 kb on - strandat 1053.326 kb on - strandat 1053.366 kb on - strandat 1053.368 kb on - strandat 1053.401 kb on + strandat 1053.559 kb on + strand, within BBR_RS14615at 1053.559 kb on + strand, within BBR_RS14615at 1054.002 kb on + strand, within BBR_RS14615at 1054.010 kb on - strand, within BBR_RS14615at 1054.021 kb on + strand, within BBR_RS14615at 1054.033 kb on + strand, within BBR_RS14615at 1054.088 kb on + strand, within BBR_RS14615at 1054.158 kb on + strand, within BBR_RS14615at 1054.160 kb on + strand, within BBR_RS14615at 1054.165 kb on + strand, within BBR_RS14615at 1054.168 kb on - strand, within BBR_RS14615at 1054.168 kb on - strand, within BBR_RS14615at 1054.168 kb on - strand, within BBR_RS14615at 1054.168 kb on - strand, within BBR_RS14615at 1054.173 kb on - strand, within BBR_RS14615at 1054.173 kb on - strand, within BBR_RS14615at 1054.175 kb on + strand, within BBR_RS14615at 1054.188 kb on - strand, within BBR_RS14615at 1054.235 kb on + strand, within BBR_RS14615at 1054.235 kb on + strand, within BBR_RS14615at 1054.413 kb on - strand, within BBR_RS14615at 1054.565 kb on - strand, within BBR_RS14615at 1054.603 kb on + strand, within BBR_RS14615at 1054.623 kb on + strand, within BBR_RS14615at 1054.698 kb on - strand, within BBR_RS14615at 1054.707 kb on - strand, within BBR_RS14615at 1054.707 kb on - strand, within BBR_RS14615at 1054.709 kb on + strand, within BBR_RS14615at 1054.774 kb on - strand, within BBR_RS14615at 1054.865 kb on + strand, within BBR_RS14615at 1054.929 kb on + strand, within BBR_RS14615at 1054.983 kb on + strand, within BBR_RS14615at 1055.123 kb on + strand, within BBR_RS14615at 1055.142 kb on + strand, within BBR_RS14615at 1055.165 kb on + strand, within BBR_RS14615at 1055.184 kb on + strand, within BBR_RS14615at 1055.246 kb on + strand, within BBR_RS14615at 1055.249 kb on - strand, within BBR_RS14615at 1055.258 kb on + strand, within BBR_RS14615at 1055.309 kb on + strand, within BBR_RS14615at 1055.364 kb on - strand, within BBR_RS14615at 1055.382 kb on - strand, within BBR_RS14615at 1055.428 kb on + strand, within BBR_RS14615at 1055.444 kb on + strand, within BBR_RS14615at 1055.593 kb on + strandat 1055.688 kb on - strandat 1055.688 kb on - strandat 1055.705 kb on + strandat 1055.715 kb on - strandat 1055.727 kb on + strandat 1055.738 kb on + strandat 1055.752 kb on - strandat 1055.752 kb on - strandat 1055.786 kb on - strandat 1055.804 kb on + strandat 1055.812 kb on - strandat 1055.875 kb on + strandat 1055.877 kb on - strandat 1055.965 kb on + strandat 1055.965 kb on + strandat 1055.965 kb on + strandat 1055.975 kb on - strandat 1055.975 kb on - strandat 1055.989 kb on + strandat 1056.058 kb on + strand, within BBR_RS14620at 1056.066 kb on - strand, within BBR_RS14620at 1056.066 kb on - strand, within BBR_RS14620at 1056.066 kb on - strand, within BBR_RS14620at 1056.066 kb on - strand, within BBR_RS14620at 1056.066 kb on - strand, within BBR_RS14620at 1056.118 kb on + strand, within BBR_RS14620at 1056.130 kb on - strand, within BBR_RS14620at 1056.137 kb on + strand, within BBR_RS14620at 1056.137 kb on + strand, within BBR_RS14620at 1056.182 kb on - strand, within BBR_RS14620at 1056.343 kb on + strand, within BBR_RS14620at 1056.344 kb on + strand, within BBR_RS14620at 1056.439 kb on + strand, within BBR_RS14620at 1056.445 kb on + strand, within BBR_RS14620at 1056.476 kb on - strand, within BBR_RS14620at 1056.476 kb on - strand, within BBR_RS14620at 1056.537 kb on + strand, within BBR_RS14620at 1056.659 kb on - strand, within BBR_RS14620at 1056.672 kb on + strand, within BBR_RS14620at 1056.708 kb on - strand, within BBR_RS14620at 1056.711 kb on - strand, within BBR_RS14620at 1056.760 kb on + strand, within BBR_RS14620

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Per-strain Table

Position Strand Gene LocusTag Fraction Recovery broth with Lacidipine 0.4 mM
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1,052,364 + -0.3
1,052,465 + +0.3
1,052,470 + -1.2
1,052,502 - -0.2
1,052,520 - -0.7
1,052,544 - +0.4
1,052,735 + BBR_RS14610 0.33 -0.1
1,052,908 - BBR_RS14610 0.55 +1.6
1,052,919 + BBR_RS14610 0.56 -0.1
1,053,013 + BBR_RS14610 0.68 -1.3
1,053,013 + BBR_RS14610 0.68 -0.6
1,053,014 - BBR_RS14610 0.68 -0.5
1,053,194 + +0.3
1,053,228 - +0.7
1,053,269 + +0.6
1,053,277 + -0.2
1,053,284 - +0.6
1,053,318 + -0.3
1,053,326 - +1.0
1,053,326 - -0.4
1,053,366 - -1.1
1,053,368 - +0.5
1,053,401 + -1.2
1,053,559 + BBR_RS14615 0.11 -3.0
1,053,559 + BBR_RS14615 0.11 -1.2
1,054,002 + BBR_RS14615 0.29 -0.3
1,054,010 - BBR_RS14615 0.29 -1.1
1,054,021 + BBR_RS14615 0.29 -1.4
1,054,033 + BBR_RS14615 0.30 -1.9
1,054,088 + BBR_RS14615 0.32 -0.2
1,054,158 + BBR_RS14615 0.35 +0.0
1,054,160 + BBR_RS14615 0.35 -0.4
1,054,165 + BBR_RS14615 0.35 +0.7
1,054,168 - BBR_RS14615 0.35 -0.5
1,054,168 - BBR_RS14615 0.35 +0.3
1,054,168 - BBR_RS14615 0.35 +0.9
1,054,168 - BBR_RS14615 0.35 -1.0
1,054,173 - BBR_RS14615 0.36 -0.6
1,054,173 - BBR_RS14615 0.36 +0.7
1,054,175 + BBR_RS14615 0.36 +0.5
1,054,188 - BBR_RS14615 0.36 -1.2
1,054,235 + BBR_RS14615 0.38 -0.9
1,054,235 + BBR_RS14615 0.38 -0.5
1,054,413 - BBR_RS14615 0.45 -1.7
1,054,565 - BBR_RS14615 0.51 -0.2
1,054,603 + BBR_RS14615 0.53 -0.7
1,054,623 + BBR_RS14615 0.54 +0.7
1,054,698 - BBR_RS14615 0.57 +0.6
1,054,707 - BBR_RS14615 0.57 -1.5
1,054,707 - BBR_RS14615 0.57 -1.8
1,054,709 + BBR_RS14615 0.57 -0.3
1,054,774 - BBR_RS14615 0.60 -0.4
1,054,865 + BBR_RS14615 0.64 -0.5
1,054,929 + BBR_RS14615 0.66 -0.2
1,054,983 + BBR_RS14615 0.68 +0.4
1,055,123 + BBR_RS14615 0.74 -0.6
1,055,142 + BBR_RS14615 0.75 -0.1
1,055,165 + BBR_RS14615 0.76 +0.7
1,055,184 + BBR_RS14615 0.77 -1.0
1,055,246 + BBR_RS14615 0.79 +0.2
1,055,249 - BBR_RS14615 0.79 -0.7
1,055,258 + BBR_RS14615 0.80 -0.4
1,055,309 + BBR_RS14615 0.82 +1.1
1,055,364 - BBR_RS14615 0.84 +0.3
1,055,382 - BBR_RS14615 0.85 -0.1
1,055,428 + BBR_RS14615 0.86 -0.3
1,055,444 + BBR_RS14615 0.87 -0.1
1,055,593 + +1.6
1,055,688 - -0.1
1,055,688 - -1.0
1,055,705 + -0.3
1,055,715 - -0.5
1,055,727 + -0.9
1,055,738 + -0.2
1,055,752 - +0.4
1,055,752 - +0.2
1,055,786 - +0.5
1,055,804 + -0.2
1,055,812 - +0.1
1,055,875 + +0.3
1,055,877 - -0.7
1,055,965 + +0.5
1,055,965 + -0.0
1,055,965 + +0.9
1,055,975 - -1.0
1,055,975 - -0.7
1,055,989 + +0.3
1,056,058 + BBR_RS14620 0.14 -0.1
1,056,066 - BBR_RS14620 0.15 -0.5
1,056,066 - BBR_RS14620 0.15 -0.4
1,056,066 - BBR_RS14620 0.15 -0.5
1,056,066 - BBR_RS14620 0.15 -0.4
1,056,066 - BBR_RS14620 0.15 -0.2
1,056,118 + BBR_RS14620 0.18 +0.0
1,056,130 - BBR_RS14620 0.19 -1.5
1,056,137 + BBR_RS14620 0.20 +0.3
1,056,137 + BBR_RS14620 0.20 +0.2
1,056,182 - BBR_RS14620 0.23 +0.7
1,056,343 + BBR_RS14620 0.34 +0.6
1,056,344 + BBR_RS14620 0.34 +0.4
1,056,439 + BBR_RS14620 0.40 +1.0
1,056,445 + BBR_RS14620 0.41 +0.4
1,056,476 - BBR_RS14620 0.43 -1.5
1,056,476 - BBR_RS14620 0.43 +0.1
1,056,537 + BBR_RS14620 0.47 +0.7
1,056,659 - BBR_RS14620 0.55 -0.7
1,056,672 + BBR_RS14620 0.56 +0.3
1,056,708 - BBR_RS14620 0.58 +0.2
1,056,711 - BBR_RS14620 0.59 -0.6
1,056,760 + BBR_RS14620 0.62 -1.2

Or see this region's nucleotide sequence