| Condition | Gene | Description | Fitness | Cons. |
|---|
| Acridine orange | Psyr_2401 | extracellular solute-binding protein, family 1 | +3.2 | |
| Acridine orange | Psyr_4819 | conserved hypothetical protein | -1.1 | |
| Acridine orange | Psyr_4837 | Heavy metal-(Cd/Co/Hg/Pb/Zn)-translocating P-type ATPase:Heavy metal translocating P-type ATPase | -1.6 | |
| Acriflavine | Psyr_2282 | Hydrophobe/amphiphile efflux-1 HAE1 | -4.0 | Yes |
| Acriflavine | Psyr_2283 | Secretion protein HlyD | -3.6 | Yes |
| Acriflavine | Psyr_4208 | heme catalase/peroxidase | -1.2 | |
| Anisodamine Hydrobromide () | Psyr_2639 | hypothetical protein | -1.9 | |
| Anisodamine Hydrobromide () | Psyr_2765 | conserved domain protein | +1.7 | |
| Anisodamine Hydrobromide () | Psyr_3436 | Response regulator receiver | -1.9 | |
| Avocadyne | Psyr_4231 | ATP-binding region, ATPase-like:Histidine kinase A, N-terminal | -1.1 | |
| Avocatin B | Psyr_3045 | PqiB family protein | -1.2 | |
| Avocatin B | Psyr_3669 | Membrane protein involved in aromatic hydrocarbon degradation | +4.6 | |
| Avocatin B | Psyr_3759 | conserved hypothetical protein | -1.6 | |
| Avocatin B | Psyr_4178 | tRNA pseudouridine synthase B | +2.5 | |
| Benzalkonium Chloride | Psyr_1543 | Peptidase M48, Ste24p | -1.4 | |
| Benzalkonium Chloride | Psyr_4819 | conserved hypothetical protein | -1.5 | Yes |
| Berberine | Psyr_2282 | Hydrophobe/amphiphile efflux-1 HAE1 | -3.4 | Yes |
| Berberine | Psyr_2283 | Secretion protein HlyD | -2.2 | Yes |
| Berberine | Psyr_4819 | conserved hypothetical protein | -1.9 | |
| Carbenicillin disodium salt | Psyr_3295 | SLT | -3.5 | Yes |
| Carbenicillin disodium salt | Psyr_4118 | Glutathione S-transferase, N-terminal:Glutathione S-transferase, C-terminal | -1.6 | |
| Carnitine (Dl) Hydrochloride | Psyr_2629 | von Willebrand factor, type A | -1.5 | |
| Chaulmoogric acid | Psyr_4293 | Acyl-CoA thioesterase | -3.0 | Yes |
| Chloramphenicol | Psyr_1639 | ribosomal large subunit pseudouridine synthase C | -1.7 | Yes |
| Erythromycin | Psyr_1543 | Peptidase M48, Ste24p | -1.6 | |
| Erythromycin | Psyr_2282 | Hydrophobe/amphiphile efflux-1 HAE1 | -3.4 | |
| Erythromycin | Psyr_2283 | Secretion protein HlyD | -3.2 | |
| Erythromycin | Psyr_3831 | ATP-dependent helicase HrpA | -1.9 | Yes |
| Erythromycin | Psyr_4819 | conserved hypothetical protein | -1.4 | |
| Fusaric acid | Psyr_0525 | Lipopolysaccharide kinase | -1.7 | |
| Fusaric acid | Psyr_0603 | N-acylglucosamine 2-epimerase | -5.0 | Yes |
| Fusaric acid | Psyr_0657 | Drug resistance transporter Bcr/CflA subfamily | variable | |
| Fusaric acid | Psyr_1543 | Peptidase M48, Ste24p | -1.5 | |
| Fusaric acid | Psyr_1584 | Aspartyl/Asparaginyl beta-hydroxylase | variable | Yes |
| Fusaric acid | Psyr_1951 | Periplasmic solute binding protein | -1.3 | |
| Fusaric acid | Psyr_2146 | methionine aminopeptidase, type I | +1.5 | |
| Fusaric acid | Psyr_3616 | Heat shock protein, Metallo peptidase, MEROPS family M48B | variable | |
| Fusaric acid | Psyr_3831 | ATP-dependent helicase HrpA | variable | |
| Fusaric acid | Psyr_4112 | Protein of unknown function UPF0011 | -1.5 | |
| Fusaric acid | Psyr_4230 | Helix-turn-helix, Fis-type | -2.1 | |
| Fusaric acid | Psyr_4231 | ATP-binding region, ATPase-like:Histidine kinase A, N-terminal | variable | |
| Fusaric acid | Psyr_4281 | cytochrome bd quinol oxidase subunit 2 apoprotein | -1.6 | |
| Fusaric acid | Psyr_4282 | cytochrome bd quinol oxidase subunit 1 apoprotein | variable | |
| Fusaric acid | Psyr_4834 | histidine:proton symporter, AAT family | -1.1 | |
| Gossypol-Acetic Acid Complex | Psyr_0603 | N-acylglucosamine 2-epimerase | -1.6 | |
| Gossypol-Acetic Acid Complex | Psyr_1943 | Sigma-70 region 2 | -2.1 | |
| Gossypol-Acetic Acid Complex | Psyr_1962 | TonB-dependent siderophore receptor | -2.8 | |
| Gossypol-Acetic Acid Complex | Psyr_1969 | ABC transporter:Protein of unknown function DUF214 | -1.8 | |
| Gossypol-Acetic Acid Complex | Psyr_1970 | Secretion protein HlyD | -2.0 | |
| Harmalol | Psyr_2282 | Hydrophobe/amphiphile efflux-1 HAE1 | -3.0 | |
| Harmalol | Psyr_2283 | Secretion protein HlyD | -2.7 | |
| Khayasin C | Psyr_0863 | PhnA protein | -1.5 | |
| L-alliin | Psyr_3703 | Flavodoxin/nitric oxide synthase | +1.3 | |
| Mitomycin C | Psyr_0098 | Protein of unknown function DUF87 | -1.1 | |
| Mitomycin C | Psyr_0278 | ABC-3 | +1.7 | |
| Mitomycin C | Psyr_0502 | potassium/proton antiporter, CPA1 family | +1.7 | |
| Mitomycin C | Psyr_0726 | ribosomal large subunit pseudouridine synthase D | +3.1 | Yes |
| Mitomycin C | Psyr_0928 | hypothetical protein | -1.4 | |
| Mitomycin C | Psyr_0938 | hypothetical protein | -1.2 | |
| Mitomycin C | Psyr_1538 | Propionyl-CoA carboxylase | -1.1 | |
| Mitomycin C | Psyr_1974 | Excinuclease ABC subunit B | -2.0 | Yes |
| Mitomycin C | Psyr_2760 | hypothetical protein | +3.3 | Yes |
| Mitomycin C | Psyr_2761 | DNA-directed DNA polymerase | +3.2 | Yes |
| Mitomycin C | Psyr_2762 | Peptidase S24, S26A and S26B | +3.0 | Yes |
| Mitomycin C | Psyr_2763 | Protein of unknown function DUF159 | +2.7 | Yes |
| Mitomycin C | Psyr_2764 | conserved hypothetical protein | +3.3 | Yes |
| Mitomycin C | Psyr_2765 | conserved domain protein | +3.8 | |
| Mitomycin C | Psyr_2770 | tail fiber domain protein | +2.1 | Yes |
| Mitomycin C | Psyr_2771 | conserved domain protein | +2.4 | Yes |
| Mitomycin C | Psyr_2772 | Fibronectin, type III | +2.4 | Yes |
| Mitomycin C | Psyr_2773 | hypothetical protein | +3.2 | Yes |
| Mitomycin C | Psyr_2775 | hypothetical protein | +3.0 | Yes |
| Mitomycin C | Psyr_2776 | hypothetical protein | +3.0 | Yes |
| Mitomycin C | Psyr_2777 | NLP/P60 | +2.7 | Yes |
| Mitomycin C | Psyr_2780 | Phage tail tape measure protein lambda | +2.7 | Yes |
| Mitomycin C | Psyr_2781 | hypothetical protein | +3.7 | |
| Mitomycin C | Psyr_2782 | hypothetical protein | +3.1 | Yes |
| Mitomycin C | Psyr_2783 | conserved hypothetical protein | +3.8 | Yes |
| Mitomycin C | Psyr_2784 | phage-related conserved hypothetical protein | +2.2 | Yes |
| Mitomycin C | Psyr_2785 | conserved hypothetical protein | +3.5 | Yes |
| Mitomycin C | Psyr_2789 | conserved hypothetical protein | +3.1 | Yes |
| Mitomycin C | Psyr_2792 | Phage putative head morphogenesis protein, SPP1 gp7 | +2.5 | Yes |
| Mitomycin C | Psyr_2793 | hypothetical protein | +2.6 | Yes |
| Mitomycin C | Psyr_2794 | Protein of unknown function DUF264 | +2.3 | Yes |
| Mitomycin C | Psyr_2795 | conserved hypothetical protein | +2.3 | |
| Mitomycin C | Psyr_2798 | hypothetical protein | +2.1 | Yes |
| Mitomycin C | Psyr_2799 | hypothetical protein | +3.3 | Yes |
| Mitomycin C | Psyr_2801 | hypothetical protein | +2.5 | Yes |
| Mitomycin C | Psyr_2805 | hypothetical protein | +3.4 | Yes |
| Mitomycin C | Psyr_2806 | Bacteriophage Lambda NinG | +4.0 | |
| Mitomycin C | Psyr_2813 | conserved hypothetical protein | +3.6 | Yes |
| Mitomycin C | Psyr_2815 | conserved hypothetical protein | +3.2 | Yes |
| Mitomycin C | Psyr_2816 | hypothetical protein | +2.6 | Yes |
| Mitomycin C | Psyr_2817 | hypothetical protein | +2.7 | Yes |
| Mitomycin C | Psyr_2821 | conserved hypothetical protein | +2.3 | Yes |
| Mitomycin C | Psyr_2825 | DNA methylase N-4/N-6 | +2.2 | Yes |
| Mitomycin C | Psyr_2827 | phage-related protein | +3.4 | |
| Mitomycin C | Psyr_2828 | C-5 cytosine-specific DNA methylase | +2.8 | Yes |
| Mitomycin C | Psyr_2834 | hypothetical protein | +2.2 | Yes |
| Mitomycin C | Psyr_2835 | hypothetical protein | +2.7 | Yes |
| Mitomycin C | Psyr_2843 | C-5 cytosine-specific DNA methylase | +1.9 | Yes |
| Mitomycin C | Psyr_2846 | Phage integrase:Phage integrase, N-terminal SAM-like protein | +1.3 | Yes |
| Mitomycin C | Psyr_3003 | [Acyl-carrier protein] phosphodiesterase | +7.1 | Yes |
| Mitomycin C | Psyr_4197 | DNA replication and repair protein RecN | -2.4 | Yes |
| Mitomycin C | Psyr_4357 | HopAJ2 protein | -1.4 | |
| Mitomycin C | Psyr_4520 | Excinuclease ABC subunit A | -1.5 | Yes |
| Mitomycin C | Psyr_4971 | Sel1-like repeat protein | -1.5 | |
| Mitomycin C | Psyr_4996 | hypothetical protein | -1.7 | |
| Nalidixic acid sodium salt | Psyr_0525 | Lipopolysaccharide kinase | -1.4 | |
| Nalidixic acid sodium salt | Psyr_0626 | DedA | +2.8 | Yes |
| Nalidixic acid sodium salt | Psyr_0937 | mannose-6-phosphate isomerase, type 2 / mannose-1-phosphate guanylyltransferase (GDP) | +2.2 | |
| Nalidixic acid sodium salt | Psyr_1259 | Exodeoxyribonuclease VII large subunit | -1.5 | Yes |
| Nalidixic acid sodium salt | Psyr_1453 | conserved hypothetical protein | -1.1 | |
| Nalidixic acid sodium salt | Psyr_1584 | Aspartyl/Asparaginyl beta-hydroxylase | -2.2 | Yes |
| Nalidixic acid sodium salt | Psyr_1599 | C-terminal processing peptidase-1, Serine peptidase, MEROPS family S41A | -1.5 | |
| Nalidixic acid sodium salt | Psyr_2146 | methionine aminopeptidase, type I | +2.2 | |
| Nalidixic acid sodium salt | Psyr_2282 | Hydrophobe/amphiphile efflux-1 HAE1 | -1.3 | Yes |
| Nalidixic acid sodium salt | Psyr_2837 | hypothetical protein | -1.2 | |
| Nalidixic acid sodium salt | Psyr_3137 | ATPase | -1.3 | |
| Nalidixic acid sodium salt | Psyr_3737 | transcriptional regulator, MarR family | +1.3 | Yes |
| Nalidixic acid sodium salt | Psyr_3856 | Helicase c2 | +1.2 | Yes |
| Nalidixic acid sodium salt | Psyr_3970 | Uracil-DNA glycosylase | -1.6 | Yes |
| Nalidixic acid sodium salt | Psyr_4197 | DNA replication and repair protein RecN | -1.8 | Yes |
| Nalidixic acid sodium salt | Psyr_4602 | hypothetical protein | +1.4 | |
| Nalidixic acid sodium salt | Psyr_4604 | hypothetical protein | +1.8 | |
| Nalidixic acid sodium salt | Psyr_4605 | transcriptional regulator PrtN, putative | +1.7 | |
| Nalidixic acid sodium salt | Psyr_4749 | cell division protein FtsX | +1.1 | |
| Nitrofurantoin | Psyr_0003 | DNA replication and repair protein RecF | -2.5 | Yes |
| Nitrofurantoin | Psyr_0185 | tyrosine recombinase XerC subunit | -1.2 | |
| Nitrofurantoin | Psyr_1974 | Excinuclease ABC subunit B | -4.1 | Yes |
| Nitrofurantoin | Psyr_2896 | Excinuclease ABC subunit C | -4.3 | Yes |
| Nitrofurantoin | Psyr_2913 | transcriptional regulator, LysR family | -3.1 | |
| Nitrofurantoin | Psyr_2968 | Hydrophobe/amphiphile efflux-1 HAE1 | -1.0 | Yes |
| Nitrofurantoin | Psyr_3396 | DNA replication and repair protein RecR | -3.7 | Yes |
| Nitrofurantoin | Psyr_3949 | DNA replication and repair protein RecO | -3.8 | Yes |
| Nitrofurantoin | Psyr_4197 | DNA replication and repair protein RecN | -1.1 | Yes |
| Nitrofurantoin | Psyr_4231 | ATP-binding region, ATPase-like:Histidine kinase A, N-terminal | -1.2 | Yes |
| Nitrofurantoin | Psyr_4281 | cytochrome bd quinol oxidase subunit 2 apoprotein | -1.2 | Yes |
| Nitrofurantoin | Psyr_4520 | Excinuclease ABC subunit A | -4.1 | Yes |
| Novobiocin sodium salt | Psyr_0003 | DNA replication and repair protein RecF | +1.1 | |
| Novobiocin sodium salt | Psyr_0063 | Two-component response regulator AlgR | +1.1 | |
| Novobiocin sodium salt | Psyr_0626 | DedA | +1.3 | Yes |
| Novobiocin sodium salt | Psyr_0726 | ribosomal large subunit pseudouridine synthase D | +2.0 | Yes |
| Novobiocin sodium salt | Psyr_0938 | hypothetical protein | -1.1 | Yes |
| Novobiocin sodium salt | Psyr_1090 | DNA polymerase III, chi subunit | -1.2 | |
| Novobiocin sodium salt | Psyr_1271 | ErfK/YbiS/YcfS/YnhG | -1.6 | |
| Novobiocin sodium salt | Psyr_1543 | Peptidase M48, Ste24p | -1.5 | |
| Novobiocin sodium salt | Psyr_1585 | Response regulator receiver:ATP-binding region, ATPase-like:Histidine kinase A, N-terminal | -1.2 | |
| Novobiocin sodium salt | Psyr_1609 | Aspartyl aminopeptidase | +1.2 | |
| Novobiocin sodium salt | Psyr_2146 | methionine aminopeptidase, type I | +1.1 | |
| Novobiocin sodium salt | Psyr_2805 | hypothetical protein | +1.3 | Yes |
| Novobiocin sodium salt | Psyr_3214 | Propeptide, PepSY amd peptidase M4 | -2.3 | Yes |
| Novobiocin sodium salt | Psyr_4588 | Phage GP46 | +1.1 | |
| Novobiocin sodium salt | Psyr_4834 | histidine:proton symporter, AAT family | +1.6 | Yes |
| Palmatine chloride | Psyr_0200 | conserved hypothetical protein | +1.3 | |
| Plumbagin | Psyr_0603 | N-acylglucosamine 2-epimerase | -2.7 | |
| Plumbagin | Psyr_1272 | NUDIX hydrolase | +1.1 | |
| Plumbagin | Psyr_1724 | glutamate dehydrogenase (NAD) | -1.2 | |
| Plumbagin | Psyr_2405 | transcriptional regulator, GntR family | +1.8 | |
| Plumbagin | Psyr_2913 | transcriptional regulator, LysR family | -2.8 | |
| Plumbagin | Psyr_2968 | Hydrophobe/amphiphile efflux-1 HAE1 | -1.2 | |
| Plumbagin | Psyr_2989 | 6-phosphogluconate dehydrogenase (decarboxylating) | -2.0 | |
| Plumbagin | Psyr_3112 | Putative ammonia monooxygenase | -1.4 | |
| Plumbagin | Psyr_3347 | transcriptional regulator, TetR family | +1.4 | |
| Plumbagin | Psyr_3759 | conserved hypothetical protein | -1.5 | |
| Plumbagin | Psyr_3834 | AMP-dependent synthetase and ligase | +1.1 | |
| Plumbagin | Psyr_4078 | AmpG-related permease | +1.8 | |
| Plumbagin | Psyr_4178 | tRNA pseudouridine synthase B | -1.7 | |
| Plumbagin | Psyr_4912 | amino acid ABC transporter substrate-binding protein, PAAT family | -1.5 | |
| Quercetin | Psyr_1943 | Sigma-70 region 2 | -1.8 | |
| Quercetin | Psyr_1962 | TonB-dependent siderophore receptor | -1.9 | |
| Rifampicin | Psyr_2482 | Secretion protein HlyD | -1.7 | |
| Rifampicin | Psyr_2483 | Acriflavin resistance protein | -2.8 | |
| Rifampicin | Psyr_2484 | Acriflavin resistance protein | -2.7 | |
| Rifampicin | Psyr_2485 | RND efflux system, outer membrane lipoprotein, NodT | -3.2 | |